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Ch.17-25,27
Pharmacology 3
38
Medical
Undergraduate 1
02/20/2009

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Term
Adrenergic Drugs
Definition
stimulate the sympathethic nervous system
Term
Catechololamine
Definition
substances that can produce a sympathomimetric response.
Term
Vasoactive Sympathomimetics
Definition
pressors,inotropesaka cardioselective sympathomimeticsused to support the heart during cardiac faliure or shock
Term
Adrenergic receptors
Definition
located throughout the body; are receptors for the sympathetic neurotransmitters; alpha,beta,dopaminergic
Term
Alpha 1 Adrenergic receptors
Definition
located on postsynaptic effector cells( the cell,muscle,or organ that the nerve stimulates)
Term
Alpha 2 Adrenergic receptors
Definition
located on presynaptic nerve terminals;(the nerve that stimulates the effector cells);control the release of neurotransmitters.
Term
Adrenergic Blockers
Definition
bind to adrenergic receptors, but inhibit or block stimulation of the sympathetic nervous system
Term
Beta Blockers
Definition
block stimulation of B receptors in the SNS; compete with norepinephrine and epinephrine.
Term
Cholinergic Drugs
Definition
drugs that stimulate the parasympathetic nervous system (PSNS);aka cholinergic agonists or parasympathomimetics. mimic the effects of the PSNS neurotransmitter acetylcholine
Term
Nicotinic Receptors
Definition
located on the ganglia of both the PSNS and the SNS; stimulated by the alkaloid nicotine
Term
Muscarine Receptors
Definition
located postsynaptically in the effector organs of the PSNS; smooth muscle,cardiac muscle, glands;can be stimulated by the alkaloid muscarine.
Term
Cholinergic blocking drugs
Definition
drugs that block or inhibit the actions of acetylcholine in the parasympathetic nervous system (PSNS); aka anticholinergics.
Term
Positive Inotropic Drugs
Definition
drugs that increase the force of myocardial contraction; used to treat heart muscle failure.
Term
Inotropic
Definition
force or energy of muscular contractions
Term
Chronotropic
Definition
rate of the hearbeat
Term
Dromotropic
Definition
the conduction of electrical impulses.
Term
Positive inotropic effect
Definition
increase in force and velocityof myocardial contraction (without an increase in oxygen consumption)
Term
Negative chronotropic effect
Definition
reduced heart rate
Term
Negative dromotropic effect
Definition
decreases automatically at SA node, decreases AV nodal conduction, and other effects; increased stroke volume, reduction in heart size during diastole, decrease in venous BP and vein engorgement, increase in coronary circulation,promotion of diuresis due to improved blood ciculation ( kidney's functioning better)
Term
Antidysrhythmics
Definition
drugs used for the treatment and prevention of disturbances in cardiac rhythm
Term
Dysrhythmia
Definition
any deviation from the normal rhythm of the heart
Term
Angina pectoris (Chest Pain)
Definition
when the supply of oxygen and nutrients in the blood is insufficient to meet the demands of the heart, the heart muscle aches; the heart requires a large supply of oxygen to meet the demands placed on it.
Term
Ischemia
Definition
poor blood supply to an organ
Term
Normal BP
Definition
<120 sys; <80 dias.
Term
Prehypertension
Definition
120-139 Sys; 80-89 dia
Term
Stage 1 hypertension
Definition
140-159 sys; 90-99 dia
Term
Stage 2 Hypertension
Definition
> or equal 160 sys; > or equal 100 dia.
Term
Blood pressure =
Definition
cardiac output  x  systemic vascuar resistance
Term
Hypertension
Definition
high blood pressure.
Term
Diuretic Drugs
Definition
drugs that accelerate the rate of urine formation; result in removal of Na and water.
Term
Loop diuretics: Mechanism of action
Definition
act directly on the ascending loop of henle to inhibit chloride and sodium resorption.
Term
Osmotic diuretics
Definition
work mostly in the proximal tubules; pulls water into the renal tubules from the surrounding tissues; inhibits tubular resorption of water and solutes,producing a rapid diuresis
Term
Osmotic diuretics
Definition
work mostly in the proximal tubules; pulls water into the renal tubules from the surrounding tissues; inhibits tubular resorption of water and solutes,producing a rapid diuresis
Term
Potassium Sparing diuretics
Definition
work in the collecting ducts and distal convoluted tubules;interfere with sodium potassium exchange; prevent potassium from being pumped into the tubule, thus preventing its secretion. the excretion of sodium and water is promoted.
Term
Thiazide and thiazide like diuretics
Definition
inhibit tubular resorption of sodium, chloride, and potassium ions; primarily in the distal convoluted tubules; results in water, sodium, and chloride being excreted.
Term
Anticoagulants
Definition
inhibit the action or formation of clotting factors; prevents clot formation. Have no direct effect on a blood clot that is already formed.
Term
Anti platlet drugs
Definition
inhibit platelet aggregation;prevent platlet plugs.
Term
Thrombolytic drugs
Definition
break down exisiting clots.
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