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Cell Injury
mechanisms of cell injury
12
Pathology
Undergraduate 3
09/02/2009

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Cards

Term
What are the most vulnerable components of cells?
Definition
Mitochondria, Cell Membrane, Protein Synthesis, Cytoskeleton, Genetic Apparatus
Term
What enzymes are activated by an influx of Ca?
Definition
Phospho-lipase, Proteases, ATPases, Endonucleases
Term
Irreversible cell injury
Definition
-inability to reverse mitochondrial dysfunction
-disturbances in membrane function
(esp. lysosomal membrane)
Term
ROS
Definition
Reactive Oxygen Species (toxic)
Term
Atrophy
Definition
decrease in cell size
Term
Hypertrophy
Definition
increase in cell size
Term
Hyperplasia
Definition
increase in cell number
Term
Metaplasia
Definition
change in cell type
Term
Dysplasia
Definition
atypical hyperplasia, disorderly proliferation of cells
Term
Apoptosis
Definition
programed cell death
Term
Autolysis
Definition
"self digestion, derived from lysosomes within the cell
Term
Heterolysis
Definition
digestion of cell by lysosomes from surrounding inflammatory cells
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