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Cell bio 1
biological molecules
31
Biology
Undergraduate 4
02/26/2008

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Term
what are the 5 characteristics common to all biological molecules
Definition

1. all contain carbon

2. formed by dehydration synthesis, broken by hydrolysis

3. large

4. polymers

5. polymers have stable 3-D structures

Term
what are the 4 major types of biological molecules
Definition

proteins

carbohydrates

lipids

nucleic acids

Term

describe the 4 levels of protein structure

Definition

primary - aa sequence

secondary - alpha helix and beta sheet

tertiery - folding of secondary into 3-D shape

quaternary - interactions between diff peptide chains

Term
what are examples of denaturing agents
Definition

detergants

urea

pH

heat

Term
what guide protein folding?
Definition
chaperone proteins
Term
what are the two main functions of proteins
Definition

structural

regulatory

 

Term
what are the main classes of structural proteins
Definition

cytoskeltal proteins

membrane proteins

Term
what are the main classes of regulatory proteins
Definition

hormones

enzymes

growth factors

Term
what is a general protein stain
Definition
coomassie blue
Term
what join the monomers in carbohydrates
Definition
glycosidic bonds
Term
what is an example of a simple sugar
Definition
glucose
Term
what are some examples of disaccharides
Definition

fructose

maltose

lactose

Term
what general types of sugars have carbonyl groups
Definition

aldosugar

ketosugar

Term
what are the main functions of carbohydrates?
Definition

storage (starch, glycogen)

structure (cellulose, chitin)

Term
what stain can be used to stain starch
Definition
iodine (Lugol's stain)
Term
what are the 4 classes of lipid
Definition

fatty acids

triglycerols

phospholipids

steroids

Term
what is the structure of a triglycerol
Definition

glycerol molecules bound to 3 fatty acids

Term
what is the structure of a phospholipid
Definition

glycerol molecule with

2 fatty acids and

a phosphate group

Term
what does ampipathic refer to
Definition
ampipathic referes to a molecule w/both hydrophobic and hydrophillic regions (ex. phospholipds)
Term
what type of molecule makes up cell membranes
Definition
phosphoglycerides
Term
what is the general structure of steroids
Definition
ring structures
Term
what type of stain used for lipids
Definition
sudan IV, sudan black
Term
what are the main functions of lipids
Definition

1. energy storage

2. membrane structure

3. biological functions (signaling molecuels, steroids, etc.)

Term
what type of bond joins monomers of nucleic acids
Definition
phosphodiester bonds
Term
what are the functions of nucleic acids
Definition
storage, transmission, and expression of genetic information
Term
what modifications are made between pre-mRNA and mature transcript mRNA
Definition

guanosine cap at 5'

poly A tail at 3'

Term
what stains used for nucleic acids
Definition

DAPI

acridine orange

methylene blue

Term
what is the general progression of DNA - protein
Definition

DNA transcribed to pre mRNA

pre mRNA spliced and modified

mature transcript mRNA leaves nucleus

transcript translated to protein

Term
what are organelles
Definition
membrane enclosed compartments found inside cells
Term
what is lumen
Definition
the interior of an organelle
Term
what are signal sequences
Definition

part of a protein that directs it to a specific organelle and can direct it across the membrane

- often removed by proteases afterwards

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