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Cell and Molecular Biology
Chapter 7 vocab
27
Biology
Undergraduate 1
09/28/2011

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Term
Alternative splicing
Definition
splicing of RNA transcripts from the same gene in different ways, each of which produces a distinct protein.
Term
aminoacyl-tRNA synthetase
Definition
Enzyme that attaches the correct amino acid to a tRNA molecule to form an aminoaccyl-tRNA
Term
anitcodon
Definition
Sequence of three nucleotides in a transfer RNA molecule that is complementary to the three nucleotide codon on a messenger RNA molecule; each anticodon is matched to a specific amino acid covalently attached elsewhere on the transfer RNA molecule.
Term
codon
Definition
Sequence of three nucleotides in a DNA or messenger RNA molecule that represents the instruction for incorporation of a specific amino acid into a growing polypeptide chain.
Term
exon
Definition
Segment of a eucaryotic gene that is transcribed into RNA and expressed; dictates the amino acid sequence of part of a protein.
Term
gene expression
Definition
the process by which a gene makes its effect on an cell or organism by directing the synthesis of a protein or an RNA molecule with a characteristic activity
Term
genetic code
Definition
set of rules specifying the correspondence between nucleotide triplets (codons) in DNA or RNA and amino acids in proteins.
Term
general transcription factors
Definition
Proteins that assemble on the promoters of many eucaryotic genes near the start site of transcription and load the RNA polymerase in the correct position
Term
initiator tRNA
Definition
Special tRNA that initiates translation. it always carries the amino acid methionine
Term
intron
Definition
Noncoding region of a eucaryotic gene that is transcribed into an RNA molecule but is then excised by RNA splicing to produce mRNA
Term
messenger RNA (mRNA)
Definition
RNA molecule that specifies the amino acid sequence of a protein. produced by RNA splicing (in eucaryotes) from a larger RNA molecule made by RNA polymerase as a complementary copy of DNA. it is translated into protein in a process catalyzed by ribosomes.
Term
promotor
Definition
Nucleotide sequence in DNA to which RNA polymerase binds to begin transcription
Term
protease
Definition
Enzyme such as trypsin that degrades proteins by hydrolyzing some of their peptide bonds
Term
proteasome
Definition
large protein complex in the cytosol that is responsible for degrading cytosolic proteins that have been marked for destruction by ubiquitylation or by some other means.
Term
reading frame
Definition
the set of successive triplets in which a string of nucleotides is translated into protein. an mRNA molecule is read in one of three possible reading frames, depending on the starting point.
Term
ribosomal RNA (rRNA)
Definition
any one of a number of specific RNA molecules that form part of the structure of a ribosome and participate in the synthesis of proteins. often distinguished by their sedimentation coefficient, such as 28S rRNA or 5S rRNA
Term
ribosome
Definition
particle composed of ribosomal RNAs and ribosomal proteins that associates with messenger RNA and catalyzes the synthesis of protein.
Term
ribozyme
Definition
an RNA molecule possessing catalytic properties
Term
RNA
Definition
A single stranded polynucletide in the form of a chain of covalently linked ribonucleotide subunits. it is synthesized when an RNA polymerase copies the nucleotide sequence of DNA. RNA serves a variety of functions in cells.
Term
RNA polymerase
Definition
Enzyme that catalyzes the synthesis of an RNA molecule on a DNA template from nucleoside triphosphate precursors.
Term
RNA processing
Definition
Broad term for the modifications that an RNA undergoes as it reaches its mature form. for a eucaryotic mRNA, processing typically includes capping, splicing, and polyadenylation
Term
RNA splicing
Definition
process in which intron sequences are excised from RNA molecules in the nucleus during the formation of messenger RNA.
Term
spliceosome
Definition
large assembly of RNA and protein molecules that splices introns out of pre-mRNA in eucaryotic cells.
Term
transcription
Definition
A process that uses one strand of DNA as the template to synthesize a complementary RNA sequence, sometimes termed the primary transcript, catalyzed by the enzyme RNA polymerase
Term
transfer RNA(tRNA)
Definition
Set of small RNA molecules used in protein synthesis as an interface (adaptor) between mRNA and amino acids.
Term
translation
Definition
Process by which the sequence of nucleotides in a messenger RNA molecule directs the incorporation of amino acids into protein; occurs on a ribosome.
Term
translation initiation factor
Definition
protein that promotes the proper association of ribosomes with mRNA and is required for the initiation of protein synthesis.
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