Term
Assoc w/
NSAID use, uremia, Decr mucin prod (esp elderly), reduced oxygen perfusion (altitude)
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Definition
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Term
active inflammation: neutrophils w/in epithelium above BM
This can be seen in: |
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Definition
| acute and chronic gastritis |
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Term
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Definition
Chronic gastritis, Peptic ulcer Dz, gastric lymphoma (MALToma)
anything having chornic gastritis BG:
-hyperplastic gastric polyp, adenomatous gastric polyp, |
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Term
| Virulence factors of H pylori (4 of them) |
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Definition
1. Urease- generates ammonia and incr local pH
2. Adhesins- allow bug to adhere to epithelial cells
3. flagella- allow ubg to be motile in mucus
4. Toxin- CagA- asso w/ ulcer formation & CA |
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Term
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Definition
| Chronic gastritis autoimmune type |
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Term
characterized by plasma cells
Warthin Starry silver stain
Tropic for gastric mucosa
Pit abscess |
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Definition
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Term
assoc w/: tobacco, chornic renal failure, NSAID use, H pylori
-burning aching pain
-___: usu 1/3 hrs after meal, relieved by food
-__- pain on eating, relieved a few hr later |
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Definition
Peptic ulcer dz
Duodenal ulcer: usu 1/3 hrs after meal, relieved by food
Gastric ulcer- pain on eating, relieved a few hr later |
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Term
| shock, sepsis, severe trauma, NSAID use |
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Definition
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Term
| pediatric pt after resp infxn |
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Definition
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Term
Corkscrew shaped
Incr risk of gastric CA |
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Definition
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Term
| Mulitple recurrent peptic ulcers |
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Definition
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Term
| assoc w/ familial adenomatous polyposis |
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Definition
-Fundic gland polyp
-adenomatous gastric polyps |
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Term
| 20X incr risk in Japan, chile, costa rica, E. europ |
|
Definition
| intestinal type gastric carcinoma |
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Term
|
Definition
| Signet ring adenocarcinoma |
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Term
| Linnitis plastica, Virchow's node, sister mary joseph nodule, signet ring |
|
Definition
| signet ring adenocarcinoma |
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Term
| CD19, CD20, t (11;18), NFkB |
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Definition
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Term
|
Definition
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Term
|
Definition
-H.pylori- chronic gastritis
-PUD
-Gastric hyperplastic/inflamm polyp
-Adenomatous gastric polyp
-Gastric CA
-Gastric lymphoma |
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Term
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Definition
-Autoimmune chronic gastritis
-Hypertrophic gastropathy (Menetrier dz, Zollinger Ellison)
-Fundic gland polyp |
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Term
| PUD: active ulcer has these layers |
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Definition
1. thin layer of fibrinoid debris
2. PMN infiltrate (variable)
3. active granulation tissue
4. fibrous scar (usu w/ thickened/thrombosed BVs near the base)
*There is no dysplasia of adjacent mucosa |
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Term
caused by gastrin-secretin tumors, MC in small intestine and pancrease
Endo: thickening/prominnace of gastric mucosal folds
Histo: Oxyntic mucosa in body/fundus double in thickness, w/ 5fold incr in # of parietal cells |
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Definition
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Term
Histo: ovoid in shape w/ smooth surface
-may show superficial erosion/ulceraion; cystic dilation
-Irregular elongated foveoalr glands
-Lamina propia may be edematous w/ variable amount of inflammation |
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Definition
| Gastric hyperplastic/inflamm polyp |
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Term
-Usu solitary, MC in antrum
-intestinal type epi w/ dysplasia
-Low grade: enlargment, elongation, hyperchromasia of nuclei, epitheial crowding, & pseudostratification
-Higher grade: gland w/in gland formation, cribriform structures |
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Definition
| Adenomatous gastric polyp |
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Term
| lymphoepithelial lesions- lymphs invading glands above BM |
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Definition
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Term
MC mesenchymal abd tumor
-Interstial cells of Cajal
-solitary, well circumscribed fleshy mass up to 30 cm
-Spindle cell type composed of thin elongated cells
-epithelioid type composed of epitheial appearing cells |
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Definition
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