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Cartilage
Cartilage
22
Biology
Graduate
11/26/2012

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Term
Hyaline Cartilage functions
Definition
-cushion articular surfaces
-provide structure for respiratory system
-provide template for long bone formation
-usually has pericardium, except around joints
Term
lacunae
Definition
space occupied by cells in cartilage matrix. during fixation, cells shrink but matrix does not, leaving artifact
Term
Chondrogenic cells
Definition
-cell of hyaline cartilge
-give rise to chondroblasts,
-spindle-shaped, like fibroblast
-derived from mesenchyme
-located in perichondrium
Term
Chondroblast
Definition
-cell of hyaline cartilge
-makes most of the matrix, cuboidal to round
Term
Chondrocytes
Definition
cell of hyaline cartilge
derived from chondroblasts, maintain matrix but less active than the chondroblasts.
Term
Fibers in EM of Hyaline Cartilage
Definition
Collagen Type II (major)
elastic fibers (minor)
Term
Does Hyaline Cartilage EM have a blood supply?
Definition
No
Term
Hyaline Cartilage Ground substance
Definition
-lots of water
-lots of aggrecan (proteoglycan with hyaluronic acid)
-chondronectin
Term
chondronectin
Definition
-a glycoprotein attaching chondrocytes
to collagen
-in Hyaline Cartilage Ground substance
Term
Hyaline Cartilage territorial matrix
Definition
-matrix next to chondrocyte
-lots of chondroitin sulfate (GAG)
-stains dark blue
Term
Hyaline Cartilage interterritorial matrix
Definition
-most of matrix
-stains light blue
Term
Elastic Cartilage function and location
Definition
-More flexible than
hyaline cartilage but provides some rigidity
-Found in auricle of the ear, walls of the auditory
canals, epiglottis, and larynx.
Term
Elastic cartilage structure
Definition
-cells are yellow in real life
-has pericardium
Term
Elastic Cartilage matrix
Definition
-matrix has tons of elastic fibers and type II collagen
Term
Fibrocartilage structure
Definition
-intermediate between dense connective tissue and hyaline cartlige
-NO pericardium
-contains type I collagen
Term
Fibrocartilage locations
Definition
1. in IV
2. connects tendons to hyaline cartilage and bone, joins
pubic symphysis, forms menisci of knee.
Term
embryo and fetal growth of cartilage
Definition
mesenchymal cells (embryonic fibroblasts) round up and divive --> mesenchyme differencate into chondroblasts --> chondroblasts secrete matrix
Term
interstitial growth
Definition
division of chondroblasts and
chondrocytes from within the cartilage
Term
appositional growth
Definition
division of chondrogenic cells in
the perichondrium and their differentiation into
chondroblasts that divide and produce cartilage
beneath the periosteum.
Term
Hormonal Stimulators of cartilage cells:
Definition
IGF-1, thyroid hormone, and testosterone
Term
Hormonal Inhibitors of cartilage cells
Definition
cortisone and estradiol.
Term
Micro fracture
Definition
surgical technique where small holes
are created on the bone surface of a joint where the cartilage has
been lost. This causes bleeding and fibrocartilage formation on
the surface of worn joint surfaces.
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