Term
| Variant (Prinzmetals) Angina |
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Definition
| Due to vasospams of coronary vessels, may occur at rest, same time each day |
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Term
| *Nitroglycerin (Nitro-bid, Nitrostat) |
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Definition
Vasodilator (decreases preload), dilates coronary arteries, *relaxes peripheral veins
Available in many dosage forms & effective for all types of angina; can be used just before exertion to prevent attack; *tolerance may develop |
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Term
| *Isosorbide dinitrate (Isordil) |
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Definition
Vasodilator (decreases preload), dilates coronary arteries, *relaxes peripheral veins
Used for prophylaxis of angina (not stable) |
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| Onset 45min; lasts 10-12h |
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Patient must have nitrate free interval or tolerance will develop
Nitrates effective for all types of angina
May be used prophylactically to prevent an angina attack
Avoid alcohol & erectile dysfunction pills while on nitrates |
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Term
Atenolol (Tenormin)
Propanolol (Inderal) |
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Definition
Beta-blockers; decrease work of heart
NOT used for variant angina
Do not d/c abruptly!
SE = sedation, no exercise tolerance |
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Term
Verapamil (Isopten)
Nifedipine (Procardia)
Amlodipine (Norvasc) |
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Definition
CCB; dilate coronary arteries
Good for all angina & pts w/ low EF
Reflex increase HR (esp. nifedipine) |
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