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Cardiovascular System
Cardiovascular and related systems
42
Anatomy
Professional
08/05/2009

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Cards

Term
systole
Definition
contraction and emptying
Term
diastole
Definition
relaxation and filling
Term
foramen ovale
Definition
hole in the septum that connects the L & R sides of the heart in fetuses
Term
ductus arteriosus
Definition
connection between aorta and pulmonary artery
Term
Sinoatrial node
Definition
the pacemaker of the heart (controlled by brain)
Term
Atrioventricular node (AV node)
Definition
in the septum, 2nd point in conducting system of heart
Term
Atrioventricular bundle (of HIS)
Definition
3rd step in conducting system of heart
Term
L and R bundle branches
Definition
network of purkinje fibers spread myogenic signal from bundle of HIS
Term
what percentage of blood goes to cornary arteries?
Definition
5%
Term
function of coronary arteries
Definition
branch out of ascending aorta into L & R coronary arteries carrying oxygenated blood to muscles of the heart. branches into smaller vessels providing blood to rest of heart. connected by collaterals.
Term
function of cardiac veins
Definition
carry deoxygenated blood back
Term
stroke volume
Definition
the amount of blood pumped out of the heart after one cardiac cycle
Term
cardiac output
Definition
total amount of blood that leaves the heart in one minute
Term
3 layers of veins & arteries
Definition

1. tunica intima

2. tunica media

3. tunica adventicia

Term
composition of blood
Definition

45% plasma

55% cells

Term
what's in plasma
Definition
water, gasses, nutrients, waste, hormones, etc.
Term
functions of blood
Definition
  • tx of gasses, nutrients, waste, hormones...
  • defense mechanism
  • prevention of blood loss
  • controls body temp

Term
where are blood cells created?
Definition
from pluripotent stem cells in red bone marrow
Term
what hormone controls blood production?
Definition
erythropoietin
Term
what organ secretes the hormone responsible for erythropoiesis?
Definition
kidney
Term
erythropoiesis
Definition
process of red blood cell creation
Term
characteristics of RBCs
Definition
  • biconcave
  • non-nucleated
  • life span approx 120 days
  • contains haemoglobin
Term
where are RBCs destroyed
Definition
spleen & liver
Term
what nutrients are required for cell maturation?
Definition
vitamin B12 and folic acid
Term
what is required for vitamin B12 absorption?
Definition
intrinsic factor (in intesines)
Term
hypoxia
Definition
fall of oxygen levels in the blood
Term
haemolysis
Definition
destruction of erythrocytes
Term
which cells are responsible for haemolysis?
Definition

phagocytic reticuloendothelial cells (in the liver, spleen and bone marrow)

AKA Kupffer cells

Term
what happens to bilirubin after haemolysis?
Definition
it is transported to the liver and excreted as part of bile
Term
granulocytes
Definition
neturophils, basophils, eosionphils
Term
agranulocytes
Definition
monocytes, lymphocytes
Term
neutrophils
Definition
  • found in largest quantity
  • part of pus
  • irregular cells having a nucleus capable of phagocytic activity
  • removal of pathogens & damaged cells
  • diapedasis
Term
eosinophils
Definition
  • increases in allergic reactions & parasitic infections
  • counteracts histamine & reduces inflammatory reaction
  • produces plasmin which dissolves fibrin
Term
basophils
Definition
  • mast cells
  • secretes histamine & heparin
  • histamines increases diameter of blood vessels, increases blood flow to area
Term
monocytes
Definition
agranulocytes in blood
Term
macrophages
Definition
agranulocytes in tissue
Term
features of monoctyes
Definition
  • overall fxn is defense
  • large phagocytic cells
  • assists scar formation
  • increased in microbial infection
Term
features of lymphocytes
Definition
  • formed in bone marrow, stored in lymph. sys.
  • 2 types: T-lymphoctyes & B-Lymphocytes
Term
plateletes/thrombocytes
Definition
blood cell involved in clotting
Term
haemostasis (clotting)
Definition
  1. vasoconstriction - platelets adhere to cell wall, release serotonin, constrict vessel
  2. platelet plug
  3. coagulation
Term
coagulation
Definition

clotting factors + Ca + vit K ->

prothrombin -> thrombin ->

fibrinogen -> fibrin strands -> mesh

Term
fibrinolysis
Definition
break down of clot
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