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Cardiovascular Pathology definitions
Cardiovascular pathology definitions, Univ of TN College of Medicine
51
Pathology
Professional
08/15/2011

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Term
Anastamosis
Definition
A natural communication between two vessels; may be direct or by means of connecting channels.
Term
Aneurysm
Definition
Localized abnormal dilatation of a blood vessel, usually an artery; due to a congenital defect or weakness in the wall of the vessel. <br />
Term
Angina Pectoris
Definition
An oppressive pain or pressure in the chest caused by inadequate blood flow and oxygenation to heart muscle.
Term
Arrhythmia
Definition
Irregularity or loss of rhythm, esp. of the heart. <br />
Term
Aschoff Body
Definition
A granulomatous inflammation characteristic of acute rheumatic carditis, consisting of fibrinoid changes in connective tissue and lymphocytes.
Term
Carcinoid Heart Disease
Definition
cardiac manifestations of a systemic syndrome that includes flushing, diarrhea, dermatitis, bronchoconstriction and is caused by bioactive compounds released by carcinoid tumors. Primarily the endocardium and valves of the right heart are affected.
Term
Cardiac Tamponade
Definition
compression of the heart that occurs when blood or fluid builds up in the space between the myocardium (heart muscle) and the pericardium (outer covering sac of the heart)
Term
Cardiogenic Shock
Definition
Failure of the heart to pump an adequate supply of blood and oxygen to body tissues. <br /><br />
Term
Cardiomyopathy
Definition
Any disease that affects the heart muscle, diminishing cardiac performance. <br />
Term
Chronic Ischemic Heart Disease
Definition
(aka Ischemic Cardiomyopathy) progressive heart failure as a consequence of ischemic myocardial damage.
Term
Coarctation of the Aorta
Definition
A localized congenital malformation resulting in narrowing of the aorta, often resulting in hypertension. Surgical correction of the obstruction may cure high blood pressure in affected patients.<br />
Term
Conduction system of the heart
Definition
Specialized myocytes in the heart that conduct the electrical impulses throughout the heart. <br /><br />
Term
Congenital Heart Disease
Definition
a problem with the heart's structure and function due to abnormal heart development before birth. Congenital means present at birth.
Term
Congestive Heart Failure
Definition
Inability of the heart to circulate blood effectively enough to meet the body's metabolic needs. <br />
Term
contraction Band necrosis
Definition
a type of uncontrolled cell death (necrosis) unique to cardiac myocytes and thought to arise in reperfusion from hypercontraction, which results in sarcolemmal rupture.<br />Seen as intenesely eosinophilic transverse bands in H&amp;E.
Term
Cor Pulmonale
Definition
Hypertrophy or failure of the right ventricle resulting from disorders of the lungs, pulmonary vessels, or chest wall. <br />
Term
Coronary Artery Disease
Definition
Narrowing of the coronary arteries, usually as a result of atherosclerosis. <br />
Term
Dextrocardia
Definition
The condition of having the heart on the right side of the body.<br />
Term
Diastole
Definition
The period of cardiac muscle relaxation, alternating in the cardiac cycle with systole or contraction
Term
Ductus Arteriosus
Definition
A short vessel between the main pulmonary artery and the aortic arch of the fetus; it permits some blood to bypass the fetal lungs.<br />
Term
Ebstein Anomaly
Definition
A congenital heart condition resulting from downward displacement of the tricuspid valve from the anulus fibrosus. <br />
Term
Endocardial Fibroelastosis
Definition
Fibroelastosis (Overgrowth of Fibroelastic Tissue) of the endocardium. It leads to cardiac failure.<br />
Term
Endocarditis
Definition
Infection or inflammation of the heart valves or of the lining of the heart.
Term
Foramen Ovale (heart)
Definition
The opening between the two atria of the fetal heart; it permits blood to flow from the right atrium to the left atrium to bypass the lungs.
Term
Heart Failure (CHF)
Definition
Inability of the heart to circulate blood effectively enough to meet the body's metabolic needs.
Term
Hemopericardium
Definition
Accumulation of blood in the pericardium.<br /><br />
Term
Hypertension
Definition
High Blood Pressure<br />(In adults, a condition in which the blood pressure (BP) is higher than 140 mm Hg systolic or 90 mm Hg diastolic on three separate readings recorded several weeks apart.)<br />
Term
Hypertensive Heart Disease
Definition
Hypertensive heart disease refers to heart problems that occur because of high blood pressure. These problems include: <br /><br />•Coronary artery disease<br />•Heart failure<br />•Thickening of the heart muscle
Term
Hypertrophy of the Myocardium
Definition
Cardiac hypertrophy is a thickening of the heart muscle (myocardium) which results in a decrease in size of the chamber of the heart, including the left and right ventricles. A common cause of cardiac hypertrophy is high blood pressure (hypertension) and heart valve stenosis.
Term
Ischemic Heart Disease
Definition
Ischemic cardiomyopathy is a term that doctors use to describe patients who have reduced heart pumping (squeezing) due to coronary artery disease.
Term
Libman-Sacks Endocarditis
Definition
a form of nonbacterial endocarditis that is seen in systemic lupus erythematosus
Term
Non-infective (Marantic) Endocarditis
Definition
Nonbacterial thrombic endocarditis (NBTE) or marantic endocarditis is most commonly found on previously undamaged valves. As opposed to infective endocarditis, the vegetations in NBTE are small, sterile, and tend to aggregate along the edges of the valve or the cusps. Also unlike infective endocarditis, NBTE does not cause an inflammation response from the body (confusing, as the suffix &quot;-itis&quot; refers to inflammation). NBTE usually occurs during a hypercoagulable state.
Term
Mitral Valve Prolapse
Definition
A relatively rare condition in which the cusp or cusps of the mitral valve billow into the left atrium during systole. <br />
Term
Myocardial Infarct
Definition
The loss of living heart muscle as a result of coronary artery occlusion. <br />
Term
Myocarditis
Definition
<span style="font-weight:600;">Inflammation of the heart muscle</span>, usually as a consequence of infections (e.g., viruses, Lyme disease, rheumatic fever, trypanosomes, or toxoplasmosis); immunological-rheumatological conditions (e.g., systemic lupus erythematosus, hypersensitivity reactions, or transplant rejection); toxins (e.g., cocaine, doxorubicin); nutritional or metabolic abnormalities (e.g., thiamine deficiency or hypophosphatemia); or radiation. <br /><br />
Term
Pancarditis
Definition
Inflammation of all the structures of the heart.<br />
Term
Pericarditis
Definition
Inflammation of the pericardium, marked by chest pain, fever, and an audible friction rub. <br />
Term
Reperfusion Injury
Definition
Cellular damage that occurs after blood flow is restored to ischemic tissues.<br />
Term
Rheumatic Fever
Definition
A multisystem, febrile inflammatory disease that is a delayed complication of untreated group A streptococcal pharyngitis. <br />
Term
Rheumatic Heart Disease
Definition
Rheumatic heart disease is a condition in which permanent damage to heart valves is caused by rheumatic fever. The heart valve is damaged by a disease process that generally begins with a strep throat caused by bacteria called Streptococcus, and may eventually cause rheumatic fever
Term
Stenosis
Definition
The constriction or narrowing of a passage or orifice. <br />
Term
Sudden Cardiac Death
Definition
Sudden cardiac death (SCD) is an unexpected death due to cardiac causes occurring in a short time period (generally within 1 h of symptom onset) in a person with known or unknown cardiac disease.
Term
Systole
Definition
Contraction of the chambers of the heart.
Term
Tetralogy of Fallot
Definition
A congenital anomaly of the heart consisting of pulmonary stenosis, interventricular septal defect, dextroposed aorta that receives blood from both ventricles, and hypertrophy of the right ventricle.<br />
Term
Transpositon of the great vessels
Definition
A fetal deformity of the heart in which the aorta arises from the right ventricle and the pulmonary artery arises from the left ventricle. <br />
Term
Truncus Arteriosus
Definition
Truncus arteriosus is a rare type of congenital heart disease in which a single blood vessel (truncus arteriosus) comes out of the right and left ventricles, instead of the normal two (pulmonary artery and aorta).<br />
Term
Unstable Angina
Definition
Unstable angina is a condition in which your heart doesn't get enough blood flow and oxygen. It may be a prelude to a heart attack.<br /><br />Angina is a type of chest discomfort caused by poor blood flow through the blood vessels (coronary vessels) of the heart muscle (myocardium).<br /><br />
Term
Valvular Insufficiency
Definition
results from valve leaflets not completely sealing when a valve is closed so that regurgitation of blood occurs (backward flow of blood) into the proximal cardiac chamber.
Term
Valvular Regurgitation
Definition
A backflow of blood through a valve, esp. a heart valve, that is not completely closed as it would normally be.<br />
Term
Valvular Stenosis
Definition
a narrowing or stricture of any of the heart valves. The condition may result from a congenital defect or may be caused by disease
Term
Vegetation
Definition
A morbid luxurious outgrowth on any part, esp. wartlike projections made up of collections of fibrin in which are enmeshed white and red blood cells; sometimes seen on denuded areas of the endocardium covering the valves of the heart.<br />
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