Term
|
Definition
| Response: decrease LDL, increase TG and HDL |
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Term
|
Definition
| Response: Decrease LDL and TG, increase HDL |
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Term
| Cholesterol Absorption Blockers |
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Definition
| Response: Decrease LDL and TGs, Increase HDL |
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Term
|
Definition
| Response: Decrease LDL, TGs and VDLD, Increase HDL |
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Term
|
Definition
Response: Decrease LDL and TG, increase HDL
Increase HDL-C b/c of PPARalpha stim of apoA-I and apoA-II expression
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Term
|
Definition
Response: DECREASE SYSTEMIC VENOUS CONTRACTION (decrease work, decrease O2 needed,
Decrease filling P, decrease preload),
Decrease systemic arterial contraction (decrease work, decrease O2 needed, decrease filling pressure, decrease afterload),
Decrease pulmonary/systemic edema (decrease work),
Decrease large coronary artery contraction (increase O2 supply) |
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|
Term
|
Definition
Response: decrease HR and contractility, arterial blood pressure (decrease O2 demand), increase coronary flow via increase time in diastole (increase O2 supply)
HT: decrease CO, renin release and SNS to decrease BP (not sure how or why but it does) |
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Term
|
Definition
Response: DV: decrease HR and contractility (decrease O2 demand),
All: decrease systemic arterial contraction (decrease O2 demand) and coronary artery contraction (increase O2 supply) |
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Term
|
Definition
| Response: No affect on BP or HR, increase exercise tolerance, decrease anginal attacks |
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Term
|
Definition
| Response: PHENOMENAL decrease in risk of death or MI, can see benefits in 1st day of treat! |
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Term
|
Definition
| Response: decrease risk of death or MI, early is better |
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Term
| GP IIb/IIIa Receptor Inhibitor |
|
Definition
| Response: Decrease in risk of death or MI, early is better |
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|
Term
|
Definition
| Response: LMWH > Heparin @ reducing death or MI in combo w/aspirin in unstable angina |
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|
Term
|
Definition
| Response: reduce death or MI in ACS (acute coronary syndromes like acute myocardial ischemia) similar to heparins |
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|
Term
|
Definition
| Response: stable levels of x-coag (not yet proven beneficial in unstable angina) |
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Term
|
Definition
| Response: recanalize (re-allow flow) thrombotic occlusion, restore coronary flow, reduce infarct size, improve myocardial function and survival over short and long terms |
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|
Term
|
Definition
| Response: decrease pain, anxiety, restlessness, ANS, venous and arterial contraction (all decrease O2 demand) |
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Term
|
Definition
| Response: decrease venous and arterial contraction, SNS, and ventricular remodeling (for 2nd prevention), TPR (HT), increase renal Na/H2O excretion |
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Term
|
Definition
| Response: decrease growth of existing thrombi, prevent new thrombi formation |
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Term
|
Definition
| Response: increase renal excretion of Na, H2O, K, Ca, Mg, CI and H, relax systemic veins (increase venous capacitance): both cause decrease preload (decreased energy needs), diuretic effect causes decrease in edema (decrease in dyspnea, like in congestive heart failure) |
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|
Term
|
Definition
| Response: increase renal excretion of Na, H2O, K+, Mg++, Cl- and H+ BUT decrease Ca excretion. Diuretic effect causes decrease in edema (decrease in dyspnea) and proload (decrease E need). Lower efficacy than loop diuretics, activation of renin-angiotensin-aldosterone system (limits use in hypertension) |
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|
Term
|
Definition
| Response: increase Na, H2O excretion, decrease Ca, K, Mg and H excretion. Low efficacy alone. |
|
|
Term
|
Definition
Response: increase excretion of Na, H20, Cl, decrease excretion of Ca, K, Mg and H. Low efficacy alone. Inhibit ventricular remodeling (slows progression of disease b/c aldosterone stimulate mineralocorticoid in heart and promote fibrous lay down)
HT: monotherapy as eplerone
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|
|
Term
| Renin Angiotensin Inhibitors (HF) |
|
Definition
| Response: decrease venous and arterial contraction, VENTRICULAR REMODELING, SNS, preload and afterload, increase excretion of Na and H2O |
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|
Term
| Direct Arterial Vasodilators |
|
Definition
| Response: decrease arteriolar contraction -> decrease afterload -> decrease O2 demand (work) |
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Term
|
Definition
| Response: decrease SNS, filling pressure, edema, AV conduction, increase CO, PNS, exercise tolerance and PR (b/c slower conduction @ AV node) |
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|
Term
|
Definition
| Response: Increase CO, decrease filling P |
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Term
|
Definition
| Response: increase contractility, rate of relax, CO, decrease venous and arterial contraction (DILATE ARTERIOLES), filling pressure and pulmonary arterial contraction |
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|
Term
|
Definition
| Response: decrease venous (STRONG) and arterial contraction, and filling pressure, increase CO |
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Term
|
Definition
| Response: decrease conduction and automaticity (b/c Na block), increase refractoriness (b/c K block), QRS (slower conduction, b/c Na channel block) and QT (increased refractoriness b/c K channel block) |
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Term
|
Definition
| Response: decrease conduction, automaticity (only in abnormal, not in normal) and QT (NOT BIG CHANGE IN EKG) |
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Term
|
Definition
| Response: decrease CONDUCTION, automaticity, increase QRS (VERY marked) |
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Term
|
Definition
| Response: decrease conduction, automaticity (normal and abnormal), increase PR (delay @ AV node) |
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Term
|
Definition
| Response: increase refractoriness, QT (*), decrease automaticity and PR (minor) |
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Term
|
Definition
| Response: Decrease AV conduction, and automaticity, increase PR (delay @ AV node) |
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Term
|
Definition
| Response: Decrease AV conduction and sinus node rate, increase PR (longer conduction @ AV node) |
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|
Term
|
Definition
Response: decrease angiotensin II actions, venous and arterial contraction, SNS, TPR
Increase renal Na/H2O excretion |
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