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Cardiac Disease
cardiac disease lecture
56
Medical
Graduate
09/18/2008

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Cards

Term
What is the AntiPlatelet dosing for ASA?
Definition
40-150 mg QD (this is why we use baby aspirin at 81 mg)
Term
What is the Antipyretic; analgestic dosing for ASA?
Definition
>325 mg QD
Term
What is the anti-inflammatory dosing for ASA?
Definition
>3000mg QD
Term
Which of the types of endocarditis are IVDAs most supceptable to?
Definition
staph & fungal (r/t HIV)
Term

True or False

33% of pts with MVP get endocarditis.

Definition
True
Term
What are some s/s of endocarditis?
Definition
  • Strep infection usually w/i 2w.
  • fever, chills, nightsweats
  • valve regurg.
  • emboli
  • abscess
  • septic emboli
  • 85% have murmurs
  • 66% have CHF
Term
What exam findings are characteristic of endocarditis?
Definition
  • Janeway's legions: palms & soles
  • Osler's Nodes: pads of fingers, toes.
  • Splinter Hemorrhages: nail beds
  • Petechiae: conjunctiva, buccal mucosa.
Term

True or False

Left untreated, endocarditis in fatal 100 % of the time.

Definition
True.
Term
How does the clinical picture of endocarditis differ in the IVDA?
Definition
  • Rt. sided involvement
  • cavitary lesions on xray
  • fever, chills, pleuritic pain
  • septic emboli-lungs
  • cocaine users have left sided endocarditis.
Term
What are some s/s of systemic involvement of endocarditis?
Definition
  • splenic artery emboli
  • pericardial friction rub
  • left plural effusion
  • renal, coronary, mesentery artery emboli
  • CNS emboli.
Term
When BC return with a + result, what is ordered next for the pt?
Definition
Echo.
Term
About 1/3 of pts with endocarditis have Neuro manifestations, what might you see?
Definition
  • H/A, seizures
  • brain abscesses
  • purulent meningitis
  • younger pts present with h/a, stroke, meningitis.
  • older pts present with confusion, malaise, fatigue, and no fever.
Term
What are the odds that BCs will be negative in the presence of infective endocarditis.
Definition

5-10%

  • draw 3 sets of BC in first 24h
  • if on previous ABs-get more cultures.
  • Order UA for proteinuria/hematuria
Term
What diagnostics are ordered for the pt with endocarditis?
Definition
  1. CBC
  2. Sed rate-usually increased
  3. retic count-usually low
  4. RPR
  5. RA/ANA
Term
What is seen on an echo for a pt that has endocarditis?
Definition
95% have veggitation which could take months to clear up after the regimen of ABs.
Term
If the echo is negative for endocarditis & you stronglly susspect the pt has IE, what diagnostic should be ordered?
Definition
TEE
Term
What are some differential dx for endocarditis?
Definition
  1. If 3 BCs are neg consider: Rheumatic fever
  2. atrial myxoma
  3. PE, systemic LE
  4. Non bacterial endocarditis occurs in pts with wasting (resolves on its own).
Term
What is the management for the pt with endocarditis?
Definition
  1. strep: PCN
  2. Staph: vanco
  3. If prostetic valve: vanco, rif., genta.
  4. initially on day 1: broad spectrum.
Term
What are the different types of BCs that can be ordered on a pt with endocarditis?
Definition
  1. Hacek: tx with rocephin
  2. fungal: amphoterecin
  3. TREAT ALL FOR 4-6W
  4. DO DAILY BCs UNIL NEGATIVE
  5. 10% can have fever for >2w
Term
What are some indications that the pt with endocarditis may require Sx?
Definition
  • uncontrolled bacteremia (+BC dispite tx)
  • CHF
  • prosthetic valves
  • fungal IE
  • recurrant systemic emboli.
Term
What are some s/s of Pericarditis?
Definition
  • pericardial friction rub-diagnostic
  • Pain: worsened by coughing or laying down, relieved by sitting up & leaning forward.
  • cyanosis
  • anorexia
  • hypotension
  • substernal pain radiating to shoulder.
Term
What EKG changes could be seen in the pt with Pericarditis?
Definition
  • ST up or down
  • Sinus Tach
  • Flipped Ts
  • SVT & A-fib.
Term
The friction rub in pericarditis is diagnostic. What are some of its characteristics.
Definition
  • it has 3 components: at times only 1 or 2 maybe heard.
  • It is intermittant & variable in intensity.
  • occurs in atrial/ventricular systole
Term

True or False

The echocardiogram is the study of choice in pericarditis to show effusion.

Definition
True
Term
What are the diagnostics that should be ordered in the pt with pericarditis?
Definition
  • sed rate
  • CBC
  • Cardiac enzymes
  • fungal cultures
  • PPD
  • thyroid/renal function tests
  • ANA/RA, blood cultures.
Term

True or False

Most courses of pericarditis are self limiting & resolve in a few weeks.

Definition
True, most have complete resolution in 2w.
Term
What are some clinical indicators of pericardial effusion?
Definition
  • apical pulse maybe abscent
  • low voltage EKG
  • Cardiomegaly on CXR
  • abnormal echo
Term
What complications can be expected in the pt with Pericardial effusion?
Definition
  • depends on volume of fluid/rate of development.
  • slow: heart size expands
  • rapid: hemodynamic changes: tamponade.
Term

What is the emergency tx for pericardial effusion?

Definition
Pericardiocentesis
Term

Your 45 y.o. male pt is c/o: SOB, CP x 1h unrelieved by NTG x 3,and back pain and is diaphoretic & very anxious. WBCs are elevated & T1 is pending any minute. EKG shows sinus tach at 111.

What are your thoughts?

Definition

Normal EKGs can never exclude an infarct.  Only 50-60% show acute MI & 20% never show it.

Term
How long does it take Troponin I to rise?
Definition

It will begin to rise in 2-6h.

Note to self: Most deaths r/t MIs occur w/i the 1st 2h of infarct.

Term
30% of MIs fall into the "atypical" category. What types of pts are included in this group?
Definition
  • Women
  • non whites
  • diabetics
  • elderly
  • heart transplant pts (do not feel CP r/t MI)
Term
How long does it take for CK-MB to rise in the case of an AMI?
Definition
4-6h, consider this when Troponin I only takes 2-6h (and most MI deaths occur in first 2h)
Term
What does the acronym MONA stand for when treating the MI pt?
Definition
  • Morphine
  • O2
  • Nitro
  • ASA
Term
What is a MUGA scan?
Definition
The MUGA scan (MUltiple Gated Acquisition scan) is an extremely useful noninvasive tool for assessing the function of the heart. The MUGA scan produces a moving image of the beating heart, and from this image several important features can be determined about the health of the cardiac ventricles 
Term

True or False

The higher the HR on an echocardiogram the more inaccurate it will be.

Definition
True
Term

Myth or Fact:

20% of pts having an MI will NOT experience chest discomfort.

Definition
Fact
Term

Myth or Fact

Elderly pts (>85y) that have MIs, the most common symptom is SOB

Definition
Fact
Term

What is Levine's sign?

(hint: r/t MI)

Definition
A clutched fist or open hand on the left chest when a pt is asked where their chest discomfort is. 80% of pts having an MI will demonstrate Levine's sign.
Term
What are some less freqent locations of discomfort during an MI?
Definition
  • intrascapular region of the back (>common in females)
  • Rt side of chest
  • Rt shoulder, jaw, or ulnar aspect of rt arm.
Term
Why do we give B-bs to the pt with an MI?
Definition

lower risk of ventricular arrhythmias

decrease myocardial O2 demand

Term
Name a few ABSOULUTE contraindications to fibrinolytic therapy.
Definition
  • recent internal bleed
  • hx CVA
  • recent sx
  • uncontrolled htn
  • trauma w/i 10d
  • intracranial arteriovenous malformations
  • know bleeding diathesis
Term
What is the definition of heart failure?
Definition
occurs when the heart can no longer produce sufficient CO at normal filling pressures to meet metabolic demand. This usually occurs when the left ventricular ejection fraction falls below 40%
Term

The NP suspects that tx of pericarditis has been effective if which of the following parameters are noted:

  1. sed rate rises
  2. ST segs return to baseline
  3. pt denies CP in the upright position
  4. pts mean arterial pressure decreases from 94 to 84 mm Hg
Definition
ST segs return to baseline.
Term

The NP knows that a pt with an MI may experience pain in the jaw or shoulder because of which of the following factors:

  • ischemic heart tissue can irritate adjacent tissue causing diffuse pain.
  • areas such as the shoulder and jaw share a nerve pathway with the heart resulting in referred pain.
  • mediators relaeased from damaged heart tissue can cause increased capillary permiability, resulting in pressure on tissues adjacent to the heart.
Definition
shoulder and jaw share nerve pathways with the heart resulting in referred pain.
Term
Which of the cardiac enzymes elevate first?
Definition
Troponin I in 2-6h, but remember that death from most MIs occur in the first 2h of infarct.
Term
What is the 2y mortality rate difference between Q wave MI % Non Q wave MI?
Definition
None, both 30%
Term
What class of antihypertensives is most preferred in the pt with AMI and why?
Definition
Bb, because they reduce  myocardial oxygen demand, decrease HR & decrease BP.
Term

Exactly what does an echocardiogram evaluate?

Definition
  • valvular heart disease
  • caridac chambers
  • congenital heart disease
  • cardiac masses
  • wall motion
  • pericardial disease
Term
What is the rule of Rosner when evaluating the results of and echo?
Definition
The higher the HR, the less accurate the echo results are.
Term
What classification of cardiac disease are alcoholics prone to?
Definition
Cardiomyopathy
Term
What is systolic failure?
Definition
abnormal ejections fraction: LVF is decreased.
Term
What is diastolic failure?
Definition
Increased left ventricular end diastolic pressure, but have Normal systolic function & ejection fraction. The pressure in diastole increases, almost a normal part of aging.
Term
Whatis the earliest s/s of CHF?
Definition
dyspnea upon exertion
Term
What s/e of Bb must the NP make the pt aware of?
Definition
Tiredness
Term
what are some special considerations for the pt with CHF?
Definition
  • No NSAIDs
  • wt control, wt gain 2lbs or > =danger
  • control DM
  • exercise
  • control HTN
  • make sure 10h QD are nitrite free.
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