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Cardiac 1 quiz
cardiac 1 quiz
28
Pharmacology
Undergraduate 1
12/02/2012

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Term
A patient develops blurred vision with yellow spots while taking Digoxin. The nurse recognizes these visual changes as
Definition
Acute toxicity
Term
What is the effect of sympathetic nervous system stimulation on the heart?
Definition
Increased rate, increased force of contraction
Term
Which of the following is the goal of therapy in cardiovascular disorders?
Definition
To restore homeostasis
Term
The electrolyte imbalance that places patients at greatest risk for digoxin toxicity is...
Definition
Hypokamemia
Term
Before administering digoxin (Lanozin) the nurse should
Definition
Report decreased difficulty breathing
Term
A patient has chronic heart failure and is placed on a drug regimen that is the "standard of care" for heart failure. This regimen consist of an ACE inhibitor or ARB plus what other class of drugs?
Definition
Diuretics
Term
How is homeostasis restored in cardiovascular disorders?
Definition
Increased/Decreased cardiac output
INcreased/Decreased blood pressure
Increased/Decreased heart rate
Increased/decreased blood clotting
Alter cardiac rhythm
Alter quality of blood
Decrease chest pain in cardiac origin
Term
Major factor in atherosclerosis, Acute coronary syndrome, Hypertension, Thromboembolic disorders?
Definition
Dysfunction endothelium (smooth muscle cells) The main cause is: injury to blood vessel wall from trauma or disease.
Term
What is the role of platelets?
Definition
essential for blood coagulation. Prevents injured blood vessels from leakage. But they have no nucleus and cannot replicate.
Term
What does inotropic mean?
Definition
Ligand-gated ion channel. Channel linked receptor. (N+, K, Ca2+). Examples of these drugs are digoxin (cardiac glycoside) and phoshodiestease inhibitor, milrinone
Term
Electrolyte imbalance that could cause digoxin toxcity?
Definition
Potassium
Term
Vasopressin (anti diuretic hormone)
Definition
from the posterior pituitary gland.
Term
Signs and symptoms of digoxin toxicity
Definition
Life-threatening heart rhythm disturbances, Nausea/vomiting, appetite loss, abnormal discomfort, blurred vision
Term
Standard of care for chronic heart failure (two drug classes)
Definition
Diuretics in combination with: Antisense-converting enzyme (ACE) inhibitor and Angiotensin II reception blocker (ARB)
Digoxin (Lanoxin) beta bloker and aldosterone inhibitor may also be added
Term
What to assess before administering digoxin
Definition
HR and electrolyte levels.
Term
Is digoxin metabolized?
Definition
most is excreted by the kidneys and the rest is metabolized or excreted by non renal routes.
Term
The method of administration of digoxin that produces effective drug levels quickly
Definition
IV loading dose
Term
Patient assessment to see whether an antidysrhythmic drug is working
Definition
HR
Term
The new goal of antidysrhythmic therapy
Definition
To prevent or relieve symptoms or prolong survival, not just suppress dysrhythmias using non pharmacologic management of dysthythmias.
Term
Why do we take off a nitroglycerine patch at night
Definition
to prevent or manage nitrate tolorance
Term
Nitroglycerine with Viagra?—problem this causes
Definition
hypotension and vasodilation
Term
Nifedipine
Definition
Calcium channel blocker produce vasodilation
Term
Propranolol
Definition
beta bloker, used to reduce the frequency and severity of acute attacks of angina
Term
Quinidine
Definition
class 1A antidysrhythmi: reduces automaticity, slows conduction, and prolongs the refractory period. Can treat digoxin intoxication
Term
Lidocaine
Definition
IB antiysrhythmic used for treating serious ventricular dysrhythmicas associated with acute myocardial infarction. Cardiac catheterization, cardiac surgery, and digitalis, induced ventricular dyshythmias
Term
Aitroglycerine
Definition
Prototype for nitrites (antianginal) relax smooth muscle in blood vessel walls producing vasodilation, which relieves angial pain. Reduces venous pressure and venous reburin to the heart. Dialate corinary arteries and arterioles. (LOWERS BP)
Term
What two drugs can be used to treat dioxin toxicity?
Definition
Phenytoin and Quinidine
Term
How are peripheral and vascular disease managed?
Definition
surgery
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