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Cancer
(some found in NCLEX review set) Chap 82 - Cancer
188
Nursing
Professional
02/08/2010

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Term
1 Tbsp = ? ml
Definition
15-16 ml
Term
1 cup = ? ml
Definition
240 ml
Term
1 gr = ? mg
Definition
60 mg
Term
1 teacup = ? ml
Definition
180 ml
Term
1 tsp = ? ml
Definition
4-5 ml
Term
A client with thrombocytopenia is what kind of risk?
Definition
risk for injury
Term
A common complication of most chemotherapeutic agents
Definition
myelosupression
Term
A common diagnostic test that can help determine the presence of a sarcoma
Definition
Serum calcium - Sarcomas invade bone, thus increased calcium deposits in the blood may result.
Term
A complication of chemotherapy
Definition
It also destroys normal cells
Term
A mixed-tissue kidney tumor usually found in children
Definition
Wilms' tumor
Term
A personal history of which two CIBDs put a client at high risk for colorectal cancer?
Definition
- Ulcerative colitis
- Crohn's disease
Term
A woman in her 30's is receiving tamoxifen for breast cancer treatment. What side effects should she be aware of?
Definition
Those related to menopause. These side effects include amenorrhea, hot flashes, insomnia, and depression.
Term
Age at which women should start breast self-exams.
Definition
20
Term
Age at which women should start getting ANNUAL mammograms
Definition
40
Term
Age to start testing for colon cancer.
Definition
50
Term
Ages at which annual PSA tests should begin
Definition
50+
45+ if African-American or if a family history of prostate cancer exists.
40+ if multiple first-degree relatives were affected at an early age.
Term
Alkylating Agents
Definition
interfere with DNA synthesis
Term
Alpha-fetoprotein (AFP)
Definition
Germ-cell tumors, liver cancer
Term
Among factors that help reduce the chance of cancer are diets that are ...
Definition
low in fat and calories
Term
An occult blood test may help in the detection of which type(s) of cancer?
Definition
Colon and rectal
Term
Anaplastic cells
Definition
have little or no resemblance to cells from whith they developed
Term
Another name for tumor
Definition
Neoplasm
Term
Areas of the body that stem cells are usually taken from.
Definition
hip or sternum
Term
Aside from management of pain and control of side-effects, what is a goal of nursing intervention during cancer treatment?
Definition
maintenance of client weight
Term
At least 80% of cancers in the United States are due to __________________?
Definition
, alcohol, diet, and environmental factors (ie, mustard gas, asbestos and benzene).
Term
Because of the effects of chemotherapy on bone marrow and the GI tract, what precaution may be needed.
Definition
reverse (protective) isolation
Term
CA 125 tumor marker:
Definition
Ovarian, colorectal, and gastric cancers
Term
CAUTION
Definition

Change in bowel or bladder habits • A sore that does not heal • Unusual bleeding or discharge • Thickening or lump in breast or elsewhere • Indigestion or difficulty swallowing • Obvious change in wart or mole • Nagging cough or hoarseness

Term
Cachexia
Definition
sudden weigh-loss and malnourishment.
Term
Cancer defined
Definition
excessive growth (proliferation) of cells that lack the capabilities of normal cellular function.
Term
Cancer in situ
Definition
tumor cells that have not invaded surrounding sites
Term
Carcinoembryonic antigen (CEA):
Definition
Breast, colorectal, and lung cancers
Term
Carcinogenesis
Definition
the transformation of a normal cell into a malignant cell
Term
Carcinogens
Definition
agents that cause damage to cellular DNA that leads to the development of cancer
Term
Characteristics of a benign neoplasm
Definition
• Slow growth
• Encapsulated (contained within a fibrous cover)
• Composed of differentiated cells (resemble the cells of the tissue from which they develop)
• Lack metastasis (invasion of other tissues in the body)
Term
Characteristics of a malignant neoplasm
Definition

• Rapid growth

• Non-encapsulated

•Infiltrating and invading other tissues

• Anaplastic

• Commonly metastasized

Term
Chemotherapeutic agents are designed to be effective when?
Definition
during one or more of the phases of cell division.
Term
Chronic myeloid leukemia
Definition
Philadelphia chromosome:
Term
Common colorectal cancer risk factors
Definition
• A personal history of chronic inflammatory bowel disease
• A family history of a hereditary colorectal cancer syndrome (familial adenomatous polyposis or hereditary non-polyposis colon cancer)
Term
Complications from surgery - nursing interventions for side effects (ie, stomatitis)
Definition
- avoid alcohol
- avoid foods that cause irritation, including citrus
- use soft toothbrush
- rinse mouth thoroughly
Term
Cryosurgery
Definition
malignant tissue is frozen
Term
Cystic tumors of the ovaries and polypoid tumors from the colon may be removed as a type of ________ measure.
Definition
prophylactic (preventative)
Term
Cytology
Definition
The study of cells
Term
DRE
Definition
Digital rectal exam
Term
Decreased WBC
Definition
Leukopenia
Term
Decreased platelets
Definition
Thrombocytopenia
Term
Describes the act of cancer traveling to a new site.
Definition
metastasis
Term
Diet considerations for those on chemotherapy
Definition
- High-protein, high-calorie meals
- several small meals throughout the day
- nutritional supplements
Term
Dietary consideration for reduction of cancer risk
Definition
low fat, high fiber, low sodium
Term
Do a PSA before doing a ____________
Definition
digital rectal exam
Term
Drugs that interfere with the formation of blood vessels that grow to feed the cancer cells.
Definition
Antiangiogenic drugs (eg, endostatin, angiostatin)
Term
Education of the client receiving radiation or chemotherapy: basic principle
Definition
avoid anything that may lead to injury
Term
Electrocauterization
Definition
malignant tissue is burned
Term
Excessive growth
Definition
Proliferation
Term
External-beam radiation
Definition
treatment machine is placed away from the body.
Term
Food that helps build up WBCs
Definition
parsley
Term
Grade of tumors that closely resemble normal cells
Definition
Grade I
Term
Grading
Definition
a system of looking at abnormal cells under a microscope to determine the cells' degree of dedifferentiation or lack of maturity
Term
How can benign tumors be dangerous?
Definition
Their presence pushes against organs, disrupting their function.
Term
How many consecutive normal PAP tests would allow a client to reduce testing frequency to every 2 to 3 years?
Definition
three
Term
IV push, blocks receptors at nerve endings in the brain and GI tract.
Definition
Serotonin Antagonists
Term
Instruments used for visual observation of internal organs
Definition
sigmoidoscope, colonoscope, gastroscope, bronchoscope, and laryngoscope
Term
Largest size of a T1 tumor
Definition
1cm
Term
Loss of appetite
Definition
anorexia
Term
Measures for providing comfort for the client receiving radiation therapy.
Definition
- include calories, protein and vitamins (especially vitamin C)
- all fruits and vegetables must be peeled to reduce intake of germs.
- keep radiation site dry and free from irritation. Loose clothing advised.
- plain, tepid water. No scrubbing
- protect from sun
Term
Metastasis (M)
Definition
How much has the tumor spread?
Term
Monoclonal antibodies (MOAB, MoAb)
Definition
Highly specific antibodies that seek out and bind to specific targets on cancer cells, causing apoptosis. Produced by genetically fusing cancer cells with normal cells.
Term
Node (N)
Definition
How many nodes does the tumor have?
Term
Nursing awareness regarding interleukins
Definition
possible hypotension, edema (incl. pulmonary edema), dyspnea, and tachycardia.
Term
Nursing consideration (personal) when working with a client undergoing implanted radiation therapy
Definition
Do not stay with client longer than necessary.
Term
Nursing intervention for fatigue effect of treatment
Definition
planned activities, including rest periods
Term
Of the three types of rays involved in radiation dx and therapy, which penetrates deeply into body tissues?
Definition
gamma rays
Term
PSA
Definition
Prostate-specific antigen
Term
Philadelphia chromosome:
Definition
Chronic myeloid leukemia
Term
Place where cancer starts
Definition
primary site
Term
Radiation or chemotherapy clients should not receive suppositories? Why?
Definition
clients to avoid all activities that could injure cutaneous or mucous tissues
Term
Recommended as an alternative to commercial mouthwash
Definition
• 1 teaspoon salt • ½ teaspoon baking soda • 500 milliliters water (1 cup)
Term
Recommended frequency of colonoscopy exams
Definition
Every 10 years.
Term
Removal of part of a tumor for evaluation
Definition
incisional tissue biopsy
Term
Replaces stem cells
Definition
bone marrow transplant
Term
Scheduling of pain control medications
Definition
"Around the clock" - aimed at prevention of pain.
be prepared to treat breakthrough pain
Term
Signs and symptoms of cancer
Definition
• General, unexplained feelings of discomfort
• Prickling, tingling, tightness, soreness that does not go away
• Weakness
• Unexplained loss of weight
• Abnormal findings on breast self-examination (BSE) or testicular self-examination (TSE)
Term
Special care in cleaning up chemotherapy spills
Definition
• use gloves
• special container needed for disposal
Term
Stomatitis
Definition
inflammation of the mouth
Term
TNM
Definition
Tumor, node and metastasis
Term
TRUE OR FALSE: A gene is the code for one DNA molecule.
Definition
FALSE - A gene is a segment of a DNA molecule
Term
TRUE OR FALSE: Chromosomes are made of DNA and protein
Definition
TRUE
Term
TRUE OR FALSE: In any human cell, most of the genes are always active.
Definition
FALSE
Term
TRUE OR FALSE: Messenger RNA carries the genetic code to the cell membrane
Definition
FALSE - It carries the code to the ribosome
Term
TRUE OR FALSE: Mitosis is necessary only for growth of the body.
Definition
FALSE - it is also necessary for the healing process.
Term
TRUE OR FALSE: Mutations are how cells become malignant.
Definition
TRUE
Term
TRUE OR FALSE: The process of mitosis produces two identical cells with 23 chromosomes each.
Definition
FALSE - 23 PAIRS of chromosomes each
Term
TRUE OR FALSE: Transfer RNA brings amino acids to the proper sites on the DNA
Definition
FALSE - it brings amino acids to the ribosome
Term
Teratomas, commonly found in the ovaries or testies, are of what type?
Definition
mixed-tissue
Term
Test designed to detect cervical cancer
Definition
PAP test (or PAP smear)
Term
The best time to have a mammogram done.
Definition
Two weeks after a period.
Term
The body uses its own defenses against tumor cells
Definition
biotherapy
Term
The chromosome number for a human cell
Definition
46
Term
The following conditions will likely be reason for the need for emotional support.
Definition
- Hair loss in women
- enlarged breasts in men
- general feelings of despair or discouragement.
- decreased sexual interest
-
Term
The largest group of cancer (tissue) types
Definition
Carcinomas
Term
The major cause of adult deaths in the US
Definition
Heart disease
Term
The mechanism of chemotherapy
Definition
Damage the DNA within these abnormal cells and cause self-destruction (apoptosis).
Term
The study of cells
Definition
Cytology
Term
These solid tumors develop from epithelial tissues that line skin, glands, gastrointestinal (GI), urinary, and reproductive organs.
Definition
Carcinomas
Term
These tumors develop from connective tissues, such as cartilage, bone, fat, muscle, bone marrow, and the lymphatic system.
Definition
Sarcomas
Term
They promote the immune response of the T lymphocytes
Definition
Interleukins (IL)
Term
They protect normal cells from invasion by intracellular parasites, including viruses
Definition
Interferons (IFN)
Term
Three general categories of cancer
Definition
carcinomas, sarcomas, and mixed tissue types
Term
Three places stem cells can be found
Definition
- bone marrow
- peripheral blood
- in umbilical cord blood
Term
Three surgical procedures used to prevent growth and spread of cancer
Definition
Cryosurgery
Electrocauterization
Fulgeration
Term
Tumor (T)
Definition
How big is the tumor?
Term
Tumor cells that closely resemble normal cells
Definition
Grade 1
Term
Tumor marker for breast, colorectal, and lung cancers
Definition
Carcinoembryonic antigen (CEA)
Term
Tumor marker for germ-cell tumors, liver cancer
Definition
Alpha-fetoprotein (AFP)
Term
Tumor marker for ovarian, colorectal, and gastric cancers
Definition
CA 125 tumor marker
Term
Tumor markers
Definition
specific enzymes, cancer antigens, oncofetal proteins, hormones, or genes that can indicate malignancies.
Term
Two possible types of tumors
Definition
benign and malignant
Term
Type AND frequency of enema done to test for colon and/or rectal cancer
Definition
double-contrast barium enema - every five years
Term
Types of tumors
Definition
Carcinomas
Sarcomas
Mixed tissues
Term
Under what conditions could a woman stop having PAP tests?
Definition
If she has had a total hysterectomy AND it wasn't done as a cancer treatment.
Term
Unusual bleeding or spotting after menopause is a sign of what?
Definition
Endometrial (uterine) cancer
Term
Used to determine if the cancer has spread
Definition
excisional biopsy
Term
What are tumors or neoplasms?
Definition
Growths that arise from normal tissue.
Term
What can be applied to areas in the mouth affected by stomatitis?
Definition
vitamin E
Term
What dietary adjustment should be the focus for cancer treatment?
Definition
Reduction in intake of fats and calories
Term
What do sealed mold internal radiation devices need (from nurses)?
Definition
protective protocols for nursing care.
Term
What is the confirming test to be done if a colon screening test results positive?
Definition
Colonoscopy
Term
What is the main charactristic of cancer?
Definition
Proliferation
Term
What makes cancer cells dangerous?
Definition
They invade normal tissue.
Term
What makes cancer cells different from normal cells?
Definition
They lack the capabilities of normal cell function.
Term
What should the nurse watch for during administration of monoclonial antibody treatment?
Definition
severe anaphylactic reactions
Term
When is a client considered cured of a disease?
Definition
after 5 years total remission
Term
When should cervical cancer screening begin?
Definition
Age 21 or 3 years after beginning vaginal intercourse.
Term
Which cancer treatment drug causes hot flashes?
Definition
tamoxifen (Nolvadex)
Term
Which cancer treatment drug makes urine red and causes hair loss
Definition
doxorubicin HCl (Adriamycin)
Term
Which ethnic group is at highest risk for prostate cancer
Definition
African-American
Term
Why do chemotherapy and radiation therapy result in hair loss?
Definition
all rapid-growing cells are affected.
Term
Xerostomia
Definition
dry mouth
Term
a swish-and-swallow solution that often contains a mixture of diphenhydramine (Benadryl), viscous Xylocaine, and antacid is used. The nurse advises the client to swallow only small amounts. Why?
Definition
The mixture will anesthetize the throat and may cause difficulty in swallowing, talking, or even breathing.
Term
a system of looking at abnormal cells under a microscope to determine the cells' degree of dedifferentiation, or lack of maturity
Definition
Grading
Term
agents that cause damage to cellular DNA that leads to the development of cancer
Definition
Carcinogens
Term
alopecia
Definition
hair loss
Term
apheresis
Definition
removal of peripheral blood through a large vein of blood that is then sent via tubing through special collection filters in a machine
Term
biotherapy
Definition
The body uses its own defenses against tumor cells
Term
blood condition that places patient at risk of infection
Definition
leukopenia
Term
bone marrow depression
Definition
myelosuppression
Term
can be used to excise precise areas of tumors such as on the glottis
Definition
Laser surgery
Term
can improve the client's immune response to cancer and interfere with the growth of cancer cells.
Definition
MOABs
Term
depression of WBCs
Definition
neutropenia
Term
dietary recommendation in response to stomatitis:
A) a clear, full-liquid diet
B) a soft, bland, tepid diet
C) a high-protein diet.
D) TPN
Definition
B
Term
dry mouth
Definition
xerostomia
Term
dry mouth
Definition
Xerostomia
Term
fulguration
Definition
malignant tissue is destroyed by high-frequency current.
Term
hair loss
Definition
alopecia
Term
highly specific antibodies that seek out and bind to specific targets on cancer cells, causing apoptosis.
Definition
Monoclonal antibodies (MOAB, MoAb)
Term
include the hydrocarbons found in cigarettes, cigars, and pipe smoke
Definition
chemical carcinogens
Term
indicated by an absence of all signs of a disease
Definition
remission
Term
inflammation of the mouth
Definition
stomatitis
Term
inflammation of the mucous membranes, such as in the mouth and throat
Definition
Mucositis
Term
made by lymphocytes, enhance the effects of the immune system
Definition
Interferons (IFN)
Term
metastatic sites
Definition
Secondary sites or secondary lesions
Term
mutation of a cell occurs at the ______ level
Definition
genetic
Term
myelosuppression
Definition
bone marrow depression
Term
neutropenia
Definition
depression of WBCs
Term
nursing diagnoses for nausea and vomiting
Definition
imbalanced nutrition
Term
prevent DNA replication
Definition
Antitumor Antibiotics
Term
produced by genetically fusing cancer cells with normal cells
Definition
Monoclonal antibodies (MOAB, MoAb)
Term
radioactive implants deliver ionizing radiation from within the tumor or a body cavity
Definition
internal brachytherapy, interstitial irradiation, intracavity irradiation
Term
removal of peripheral blood through a large vein of blood that is then sent via tubing through special collection filters in a machine
Definition
apheresis
Term
remove the tumor as well as some of the margin of the tumor
Definition
excisional biopsy
Term
side effects of interferon use
Definition
flu-like symptoms
Term
signs of internal bleeding
Definition
• vomitus may be appear bright red (fresh) or like coffee grounds (old).
• stools may look black and tarry
Term
special consideration when using monoclonal antibodies
Definition
acute anaphylactic reaction
Term
specific enzymes, cancer antigens, oncofetal proteins, hormones, or genes that can indicate malignancies.
Definition
Tumor markers
Term
sudden weight-loss and malnourishment.
Definition
cachexia
Term
surgery or procedure intended to relieve complications, not to cure
Definition
palliative
Term
system of looking at abnormal cells under a microscope to determine the cells' degree of dedifferentiation, or lack of maturity
Definition
Grading
Term
term to describe substances that poison cells
Definition
cytotoxic
Term
the leading cause of cancer death for both men and women
Definition
lung cancer
Term
the most important means of diagnosing cancer.
Definition
Biopsy examination
Term
the second leading cause of death by cancer in men.
Definition
Prostate cancer
Term
the transformation of a normal cell into a malignant cell
Definition
Carcinogenesis
Term
therapeutic indications for chemotherapy
Definition
• To treat widespread or metastatic disease
• To provide a cure for clients with certain types of cancer
• To temporarily control or palliate (relieve) tumor-related difficulties
• To use as an adjuvant (assistive) therapy
Term
third most common malignancy and cancer death site for men and women
Definition
Colorectal cancer
Term
treatment machine is placed away from the body.
Definition
external-beam radiation
Term
tumor cells that have not invaded surrounding sites
Definition
Cancer in situ
Term
tumors that are very anaplastic, often having little or no resemblance to the tissue cells from which they developed
Definition
Grade V
Term
use of drugs to combat cancer
Definition
chemotherapy
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