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Cancer Translocations
Cancer Translocations
7
Medical
Post-Graduate
05/05/2013
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Term
AML M3 Variant (Acute Promyelocytic Leukemia)
 Definition
t(15;17) --> RAR (chr.17) to PML (chr.15)
Term
Ewing Sarcoma
 Definition
t(11;22) --> EWS gene
Term
Mantle Cell Lymphoma (NHL)
 Definition
t(11;14) --> over-express cyclin D1
Term
Burkitt's Lymphoma
 Definition
t(8;14) t(2;8) t(8;22)

c-MYC & IgH
Term
CML
 Definition
t(9;22) --> BCR-ABL
Term
Follicular Lymphoma
 Definition
t(14;18) --> Bcl2 overexpression
Term
Neuroblastoma
 Definition
n-MYC
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