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Four major phospholipids in mammalian plasma membranes |
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-Biological membranes are composed of a continuous lipid bilayer with embedded proteins.
- The bilayer is fluid at physiologic temperatures.
-The membrane lipids are amphipathic, and the most numerous are phospholipids.
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Key Points of Membranes II |
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- The membranes are asymmetric, with varying distributions between cells or even cellular compartments.
- The head groups of some lipids form docking sites for specific cytosolic proteins.
-Some extracellular signals activate phospholipases that cleave selected phospholipid molecules in the plasma membrane, generating fragments that act as intracellular signaling molecules.
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- Fluorescence Recovery After Photobleaching |
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- Fluorescence Loss In Photobleaching |
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