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BSI- Lecture 1
Lecture 1- BSI
79
Science
Graduate
08/17/2013

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Term
The 7 main organic elements
Definition
Carbon, Hydrogen, Oxygen, Nitrogen, Phosphorous, Calcium, and Sulphur. (CHONPCS)
Term
Macromolecules are made up of:
Definition
Nucleic acids, protein, lipids, and carbohydrates
Term
Basic structural and function unit of an organism
Definition
cell
Term
Smallest living unit of the body
Definition
Cell
Term
disease due to cellular process gone awry
Definition
cellular
Term
drugs act a ______ level
Definition
cellular
Term
Group of cells work together to perform a particular function
Definition
Tissue
Term
Types of tissue
Definition
Nervous, muscle, connective, and epithelial
Term
a structure of two or more tissues working together
Definition
organ
Term
Group of related organs that have a common function
Definition
organ systems
Term
Selective barrier between internal and external environment
Definition
Plasma Membrane
Term
Composed of lipid bilayer; contains membrane proteins and cholesterol
Definition
Plasma membrane
Term
The two parts of the cytoplasm
Definition
Cytosol and cytoskeleton
Term
Fluid portion of cytoplasm that surrounds the organelles
Definition
cytosol
Term
Constitutes 55% of total cell volume
Definition
Cytosol
Term
Serves as a scaffold that helps to determine a cell's shape and to organize the cellular contents
Definition
Cytoskeleton
Term
Three types of cytoskeleton
Definition
Actin (microfilaments), intermediate filaments, and microtubules
Term
Control cell structure/shape
Definition
actin (microfilaments)
Term
Essential for movement of whole cells
Definition
Actin
Term
two stranded filament made of actin protein
Definition
Actin
Term
Most durable type of cytoskeleton
Definition
Intermediate filaments
Term
Provides cells with mechanical strength
Definition
intermediate filaments
Term
The proteins that make up intermediate filaments are _____
Definition
Cell-type specific
Term
Hollow tubes amde from protein tubulin
Definition
Microtubules
Term
Grow and radiate out from the centrosome
Definition
microtubules
Term
constantly dissembling and reassembling- very dynamic
Definition
microtubules
Term
anchors organelles
Definition
Microtubules
Term
act as a guide for intracellular transport
Definition
microtubules
Term
_____ and _____ are motor proteins that walk along the microtubules carrying cargo
Definition
kinesin and dynein
Term
form mitotic spindle during mitosis
Definition
microtubules
Term
Form cilia and flagella
Definition
Microtubules
Term
Location of DNA containing the majority of a cell's genes
Definition

controls cellular structure 

directs cellular activity 

Term
The nuclear envelope contains both the
Definition
Inner Nuclear membrane and the Outer Nuclear membrane.
Term
Is in contact with the nuclear lamina
Definition
Inner Nuclear membrane
Term
is countinous with ER
Definition
Outer nuclear membrane
Term
Filamentous network of proteins (lamins) within nucleus
Definition
Nuclear lamina
Term
binds to chromatin and inner membrane of nuclear envelope
Definition
Nuclear lamina
Term
Gives structural support to the nuclear envelope
Definition
Nuclear lamina
Term
site of all traffic between nucleus and cytoplasm
Definition
nuclear pores
Term
composed of >50 proteins called nucleoporins
Definition
Nuclear pore complex (NPC)
Term
small water-soluble molecules can freely diffuse through
Definition
Nuclear pore compex (NPC)
Term
Larger molecules (RNA, Protein) are regulated
Definition
Nuclear pore complex (NPC)
Term
Cluster of protein, DNA, and RNA within nucleus
Definition
nucleolus
Term
Where transcription of rRNA genes and assembly of ribosomes occur
Definition
Nucleolus
Term
Membranous sacs continuous with outer membrane of nuclear envelope
Definition
Endoplasmic reticulum
Term
Site of protein synthesis for proteins that need to be transported; these proteins may be targeted to the plasma membrane or secreted out of the cell
Definition
Rough ER (RER)
Term
Site of phospholipid synthesis
Definition
Rough ER
Term
Glycosylation occurs where?
Definition
Rough ER
Term
Promotes protein folding
Definition
Glycosylation
Term
can make proteins more resistant to proteolysis
Definition
Glycosylation
Term
plays a role in cell-cell recognition
Definition
Glycosylation
Term
plays a role in cell-cell adhesion
Definition
Glycosylation
Term
plays a role in cell signaling
Definition
Glycosylation
Term
Site of fatty acid and steroid synthesis
Definition
Smooth ER
Term
Site of drug inactivation and detoxification of other harmful substances
Definition
Smooth ER
Term
Calcium Storage
Definition
Smooth ER
Term
Modifies proteins
Definition
Golgi Apparatus
Term
Golycosylation (in addition to the RER) is an example of the Golgi apparatus...
Definition
Modifying proteins
Term
packages and transports proteins received from the rough ER
Definition
Golgi apparatus
Term
Forms secretory vesicles for proteins to be exocytosed
Definition
Golgi apparatus
Term
forms membrane vesicles that ferry new molecules to plasma membrane
Definition
Golgi apparatus
Term
forms transport vesicles that carry molecules to other organelles
Definition
Golgi apparatus
Term
Stack of membranous sacs, cis face, trans face
Definition
Golgi apparatus structure
Term
function of the mitochondria
Definition
Energy production (ATP production), calcium homeostasis, and plays a role in apoptosis (cell suicide)
Term
energy production (ATP production)
Definition
Mitochondria function
Term
Calcium homeostasis
Definition
Mitochondria function
Term
plays a role in apoptosis
Definition
mitochondria function
Term
apoptosis means
Definition
cell suicide
Term
mitochondria structure
Definition
Outer mitochondrial membrane, inner mitochondrial memebrane, cristae, matrix, and intermembrane space
Term
contains circular DNA with genes encoding some proteins that function in the _______
Definition
mitochondrion---mitochondria
Term
Contains digestive enzymes
Definition
Lysosomes
Term
digestion of particles and organelles (autophagy) or other cells (phagocytosis)
Definition
lysosomes
Term
contains enzymes that breakdown lipids and destroy toxic molecules by oxidation
Definition
peroxisomes
Term
pair of centrioles and pericentriolar material
Definition
centrosome
Term
are made of cylindrical array of microtubules
Definition
centrioles
Term
contains proteins that help regulate and form microtubules
Definition
centrosome
Term
builds microtubules (component of cytoskeleton)
Definition
centrosome
Term
forms mitotic spindle during cell division
Definition
centrosome
Term
function of centrosome
Definition
builds microtubules and forms mitotic spindle during cell division
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