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Brain Tumors
GBM,Meningio,Schwan,Oligo,Pilo,Medu,Ependy,Hemang,Cranio
40
Biology
Graduate
05/25/2012

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Cards

Term
MC primary brain tumor, also the worst prognosis
Definition
GBM - vs Pilocytic which is benign
Term
Crosses Corpus collosum
Definition
GBM - spreads along white matter tracts
Term
GFAP
Definition
GBM & Pilocytic - Glial fibrillary acidic protein: expressed in Astrocytes & other cells
Term
Pseudopalasading tumor cells sorrounding central necrosis & hemorrhage
Definition
GBM
Term
High grade Astrocytoma
Definition
GBM
Term
Occurs in convexities & parasaggital
Definition
Meningioma
Term
Arises from Arachnoid cells external to brain
Definition
Meningioma
Term
Psommoma body
Definition
Meningioma - Spindle cells whorling concentrically with laminated Calcifications
Term
Tumor associated with what is considered a peripheral nerve
Definition
Schwannoma - CN8 (and all CNs) are considered peripheral nerves due to being covered with schwann cells.
Term
Hearing problems
Definition
Schwannoma - usually ass with CN8
Term
S100 +
Definition
Schwannoma
Term
Found in Neurofibromatosis type 2
Definition
Schwannoma
Term
The only Infratentorial in Adults
Definition
Schwannoma
Term
Fried egg cells
Definition
Oligodendroglioma - have perinuclear halos (clearings). Cells can calcify
Term
Chicken wire capillary
Definition
Oligodendroglioma - Delicate vasculature
Term
Has endocrine symptoms & Bitemporal hemianopia. From Rathke's pouch
Definition
Pituitary adenoma
Term
Name the 5 Adult tumors
Definition
GBM, Meningio, Schwann, Oligo, Pit - "Grown Men Ordering Some Pussy"
Term
Low grade Astrocytoma
Definition
Pilocytic - Benign, vs GBM which is bad
Term
2 Kid's tumors that are Cystic with some solid nodules
Definition
Pilocytic & Craniopharyngioma
Term
Kids tumor well circumscribed and thus can be excised
Definition
Pilocytic
Term
The 2 kids tumors that can be Supratentorial
Definition
1) Pilocytic - usually Post. fossa but can be in Lobes (near GBM)
2) Cranio - Rathke's
Term
Rosenthal fibers
Definition
Pilocytic - Eosinophilic elongated cork screw fibers made of Intermediate filaments
Term
Kids tumor that involves Neurons
Definition
Medulloblastoma
Term
Kids tumor that's primitive neuroectodermal (PNET)
Definition
Medulloblastoma
Term
The 2 that Compresses 4th ventricle = Hydrocephalus
Definition
Medulloblastoma & Ependymoma
Term
Rosettes
Definition
Medulloblastoma - Tumor cells sorrounding a lumen (not to be confused with Pseudorossette which sorrounds fibril material)
Term
Pseudorossette (Homer-wright)
Definition
Medulloblastoma - Tumor cells sorrounding fibrils (not to be confused with True Rossetes which sorrounds a true lumen)
Term
Perivascular Pseudorossette
Definition
Ependymoma - Tumor cells line the blood vessel
Term
Blue cells
Definition
Medulloblastoma - these small blue cells stain blue cuz of prominent nucleus & scant cytoplasm
Term
Kids tumor that's radio-sensitive
Definition
Medulloblastoma
Term
Blepharoplasts
Definition
Ependymoma - Blepharoplasts are Ciliary bodies (Centrioles of microtubules), found near Nucleus.
Term
VHL syndrome
Definition
Hemangioblastoma, RCC, Renal cysts, Retinal angioma. Polycythemia
Term
Foamy cells
Definition
Hemangioblastoma
Term
Highly vascular
Definition
Hemangioblastoma
Term
The 2 Benign kids tumors
Definition
Pilocytic & Craniopharyngioma
Term
Often misdiagnosed as Pituitary adenoma
Definition
Craniopharyngioma - is derived from Rathke's pouch remnants = Hemianopia
Term
Can calcify with Tooth(enamel) like material
Definition
Craniopharyngioma - within Rathke's pouch
Term
Name the 5 Kids tumors
Definition
Pilocytic, Medulloblastoma, Ependymoma, Hemangioblatoma, Craniopharyngioma - "Pediatric males eat hot chicken"
Term
Name the 3 that are associated with Calcifications:
Definition
DDx based on location:
1) Meningioma - psomomma body
2) Oligodro - Fried egg cells
3) Cranio - Tooth like in Rathke's
Term
Name 3 characteristics to distinguish between Metastasized vs Primary brain tumors:
Definition
1) Met = Multicentric. Primary = singular.
2) Met are always well circumscribed.
3) Met occurs @ gray/white junction.
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