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BP Chapter 12
Sex: Evolutionary, Hormonal, and Neural Bases
70
Biology
Undergraduate 3
11/20/2013

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Term
α-fetoprotein
Definition
A protein found in the plasma of fetuses. In rodents, α-fetoprotein binds estrogens and prevents them from entering the brain.
Term
5α-reductase
Definition
An enzyme that converts testosterone into dihydrotestosterone.
Term
activational effect
Definition
A temporary change in behavior resulting from the administration of a hormone to an adult animal.
Term
allele
Definition
One of two or more different forms of a gene or genetic locus.
Term
altricial
Definition
Referring to animals that are born in an undeveloped state and depend on maternal care, as human infants do.
Term
androgen insensitivity syndrome (AIS)
Definition
A syndrome caused by a mutation of the androgen receptor gene that renders tissues insensitive to androgenic hormones like testosterone. Affected XY individuals are phenotypic females, but they have internal testes and regressed internal genital structures.
Term
anti-müllerian hormone (AMH)
Definition
A protein hormone secreted by the fetal testis that inhibits anti-müllerian duct development.
Term
appetitive behavior
Definition
The second stage of mating behavior; helps establish or maintain sexual interaction.
Term
aromatase
Definition
An enzyme that converts many androgens into estrogens.
Term
aromatization
Definition
The chemical reaction that converts testosterone to estradiol, and other androgens to other estrogens.
Term
aromatization hypothesis
Definition
The hypothesis that testicular androgens enter the brain and are converted there into estrogens to masculinize the developing nervous system of some rodents.
Term
castration
Definition
Removal of the gonads, usually the testes.
Term
cloacal exstrophy
Definition
A rare medical condition in which XY individuals are born completely lacking a penis.
Term
congenital adrenal hyperplasia (CAH)
Definition
Any of several genetic mutations that can result in exposure of a female fetus to adrenal androgens, which results in a clitoris that is larger than normal at birth.
Term
Coolidge effect
Definition
The propensity of an animal that has appeared sexually satiated with a present partner to resume sexual activity when provided with a novel partner.
Term
copulation
Definition
The sexual act.
Term
copulatory lock
Definition
Reproductive behavior in which the male’s penis swells after ejaculation so that the male and female are forced to remain joined for 5–15 minutes; occurs in dogs and some rodents, but not in humans.
Term
dihydrotestosterone (DHT)
Definition
The 5α-reduced metabolite of testosterone; a potent androgen that is principally responsible for the masculinization of the external genitalia in mammalian sexual differentiation.
Term
ejaculation
Definition
The forceful expulsion of semen from the penis.
Term
estrus
Definition
The period during which female animals are sexually receptive.
Term
external fertilization
Definition
The process by which eggs are fertilized outside of the female’s body, as in many fishes and amphibians.
Term
gamete
Definition
A sex cell (sperm or ovum) that contains only unpaired chromosomes and therefore has only half of the usual number of chromosomes.
Term
guevedoces
Definition
Literally, “eggs at 12” (in Spanish). A nickname for individuals who are raised as girls but at puberty change appearance and begin behaving as boys.
Term
indifferent gonads
Definition
The undifferentiated gonads of the early mammalian fetus, which will eventually develop into either testes or ovaries.
Term
internal fertilization
Definition
The process by which sperm fertilize eggs inside of the female’s body, as in all mammals, birds, and reptiles.
Term
intersex
Definition
Referring to an individual with atypical genital development and sexual differentiation that generally resembles a form intermediate between typical male and typical female genitals.
Term
intromission
Definition
Insertion of the erect penis into the vagina during copulation.
Term
lordosis
Definition
A female receptive posture in quadrupeds in which the hindquarters are raised and the tail is turned to one side, facilitating intromission by the male.
Term
müllerian duct
Definition
A duct system in the embryo that will develop into female reproductive structures (fallopian tubes, uterus, and upper vagina) if testes are not present.
Term
major histocompatibility complex (MHC)
Definition
A large family of genes that identify an individual’s tissues (to aid in immune responses against foreign proteins).
Term
medial amygdala
Definition
A portion of the amygdala that receives olfactory and pheromonal information.
Term
medial preoptic area (mPOA)
Definition
A region of the anterior hypothalamus implicated in the control of many behaviors, including thermoregulation, sexual behavior, and gonadotropin secretion.
Term
medullary reticular formation
Definition
The hindmost portion of the brainstem reticular formation, implicated in motor control and copulatory behavior. See
Term
musth
Definition
An annual period of heightened aggressiveness and sexual activity in male elephants.
Term
neonatal
Definition
Referring to newborns.
Term
Onuf’s nucleus
Definition
The human homolog of the spinal nucleus of the bulbocavernosus (SNB) in rats.
Term
organizational effect
Definition
A permanent alteration of the nervous system, and thus permanent change in behavior, resulting from the action of a steroid hormone on an animal early in its development.
Term
orgasm
Definition
The climax of sexual experience, marked by extremely pleasurable sensations.
Term
ovulation
Definition
The production and release of an egg (ovum).
Term
ovulatory cycle
Definition
The periodic occurrence of ovulation.
Term
ovum (pl. ova)
Definition
An egg, the female gamete.
Term
pair bond
Definition
A durable and exclusive relationship between a male and a female.
Term
parabiotic
Definition
Referring to a surgical preparation that joins two animals to share a single blood supply.
Term
paragigantocellular nucleus (PGN)
Definition
A region of the brainstem reticular formation implicated in sleep and modulation of spinal reflexes.
Term
parental behavior
Definition
Behavior of adult animals with the goal of enhancing the well-being of their own offspring, often at some cost to the parents.
Term
periaqueductal gray
Definition
The neuronal body–rich region of the midbrain surrounding the cerebral aqueduct that connects the third and fourth ventricles; involved in pain perception.
Term
phallus
Definition
The clitoris or penis.
Term
pheromone
Definition
A chemical signal that is released outside the body of an animal and affects other members of the same species.
Term
postcopulatory behavior
Definition
The final stage in mating behavior. Species-specific _ include rolling (in the cat) and grooming (in the rat).
Term
precocial
Definition
Referring to animals that are born in a relatively developed state and that are able to survive without maternal care
Term
proceptive
Definition
Referring to a state in which an animal advertises its readiness to mate through species-typical behaviors, such as ear wiggling in the female rat.
Term
refractory period
Definition
A period following copulation during which an individual cannot recommence copulation.
Term
reticulospinal tract
Definition
A tract of axons arising from the brainstem reticular formation and descending to the spinal cord to modulate movement.
Term
semen
Definition
A mixture of fluid, including sperm, that is released during ejaculation.
Term
sensitive period
Definition
The period during development in which an organism can be permanently altered by a particular experience or treatment.
Term
sex determination
Definition
The process by which the decision is made for a fetus to develop as a male or a female. In mammals this is under genetic control, but in some groups of animals, environmental variables like incubation temperature determine the sex of the offspring.
Term
sexual attraction
Definition
The first step in the mating behavior of many animals, in which animals emit stimuli that attract members of the opposite sex.
Term
sexual differentiation
Definition
The process by which individuals develop either malelike or femalelike bodies and behavior.
Term
sexual dimorphism
Definition
The condition in which males and females show pronounced sex differences in appearance.
Term
sexually dimorphic nucleus of the preoptic area (SDN-POA)
Definition
A region of the preoptic area that is five to six times larger in volume in male rats than in females.
Term
sexually receptive
Definition
Referring to the state in which an individual (in mammals, typically the female) is willing to copulate. In many species, no sexual activity is possible other than during the period of sexual receptivity in the female, which generally corresponds to ovulation.
Term
sperm
Definition
The gamete produced by males for fertilization of eggs (ova).
Term
spinal nucleus of the bulbocavernosus (SNB)
Definition
A group of motoneurons in the spinal cord of rats that innervate striated muscles controlling the penis.
Term
SRY gene
Definition
A gene on the Y chromosome that directs the developing gonads to become testes.
Term
syrinx
Definition
The vocal organ in birds.
Term
Turner’s syndrome
Definition
A condition seen in individuals carrying a single X chromosome but no other sex chromosome.
Term
ventromedial hypothalamus (VMH)
Definition
A hypothalamic region involved in eating and sexual behaviors.
Term
vomeronasal organ (VNO)
Definition
A collection of specialized receptor cells, near to but separate from the olfactory epithelium, that detect pheromones and send electrical signals to the accessory olfactory bulb in the brain.
Term
wolffian duct
Definition
A duct system in the embryo that will develop into male structures (the epididymis, vas deferens, and seminal vesicles) if testes are present in the embryo.
Term
zygote
Definition
The fertilized egg.
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