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Bone
VM 608 Midterm
44
Veterinary Medicine
Professional
04/16/2012

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Cards

Term
Scoliosis
Definition
abnormal curving of the spine
Term
Kyphosis
Definition
curving of the spine that causes a bowing or rounding of the back, which leads to a hunchback or slouching posture
Term
Exostosis
Definition
formation of new bone on the surface of a bone
Term
Chondrodysplasia
Definition
abnormally shortened and deformed limbs
Malamute autosomal recessive, defect in
organization of proliferation of physis,interference of invasion of vessels and mineralization in physis, stunted growth and valgus deformities.
Term
Osteopenia
Definition
too little bone
general term
due to disuse, senile, corticosteroids
Term
Osteoporosis
Definition
decreased in bone matrix formation
osteoblast insufficiency
Term
Rickets
Definition
osteopenia in a young animal
too little mineralized osteoid
lack of vitamin D in diet, failure to absorb Vitamin D, lack of sun, lack of conversion to active D3 in kidney
Richetic rosary-increased proliferation of cartilage ribs
Term
Osteomalacia
Definition
too little mineralized osteoid in mature animals
Term
Osteonecrosis
Definition
necrosis of bone due to loss of vascular supply
Term
Osteosclerosis
Definition
increased amount of thickened trabeculae
Term
Primary Hyperparathyroidism
Definition
Tumor/hyperplasia of parathyroid gland
Increases PTH
increases bone resorption to create osteopenia
Term
Secondary Hyperparathyroidism
Definition
Chronic Renal Disease-depressed balance of Ca:P because of failure to filtrate P, stimulates PTH and also lack of conversion to active D3 in kidney
Nutritional-Diets deficient in vitamin D, Ca, P or incorrect Ca:P balance
Term
Bran Disease
Definition
in horses
fed bran which is high in phosphate and creates imbalanced Ca:P ratio
increases PTH to increase bone resorption
Term
All Meat Diets
Definition
high in phosphorous
creates imbalance of Ca:P
increases PTH to increase bone resorption
Term
Sequestrum
Definition
isolated, avascular fragment of bone that becomes necrotic
Term
Big Head
Definition
occurs in horses when they are not getting enough Ca
osteoblasts deposit osteoid but it is unable to become mineralized
Term
Involucrum
Definition
reactive tissues surrounding a sequestrum
Term
Fracture Repair
Definition
fracture -->blood clot-->neovascularization-->blood clot organizes-->osteoclasts resorb fragments-->osteoblasts deposit bone
Term
Osteochondrosis
Definition
occurs in rapidly growing animals
interruption of the blood supply of a bone, in particular to the epiphysis, followed by localized bony necrosis, and later, regrowth of the bone.
Term
Hypertrophic Osteopathy
Definition
new bone formation on the outside of the diaphyses of long bones of the limbs, without destruction of cortical bone
Term
Hip Dysplasia
Definition
abnormal formation of the hip socket that, in its more severe form, can eventually cause crippling lameness and painful arthritis of the joints
flat acetabulum and laxity of joint
capsular fibrosis
eburnation
Term
Osteosclerosis
Definition
increased bone density
Term
Intervertebral Disc Disease
Definition
nucleus pulposa of disc ruptures
can rupture dorsally into spinal cord canal
can rupture ventrally and cause boney response
Term
Osteosarcoma
Definition
neoplasia of osteoblasts
typically in the long bone away from the elbow towards the knee
Term
Chondrosarcoma
Definition
neoplasia of the cartilage in long bones
typically in axial skeleton
Term
Fibrosarcoma
Definition
neoplasia of fibroblasts
can invade any bone
Term
Osteitis
Definition
inflammation of the bone
Term
Osteomyelitis
Definition
acute or chronic bone infection often includes periosteum
suppurative/non-suppurative
due to embolism, local trauma, extension
Actinomyces, Tuberculosis, Mycotic
Term
Lumpy Jaw
Definition
Acitinomyces bovis
chronic pyogranulomatous osteomyelitis and sinusitis
Term
Bone Response to Injury
Definition
fluid
inflammation
synovial cell proliferation
fibrosis/pannus
cartilate changes
Term
Type A Synovial cells
Definition
phagocytic, produce hyaluronic acid
Term
Type B Synovial Cells
Definition
deep in synovia, produce synovial fluid
Term
Synarthrodial
Definition
sutures in the skull
Term
Amphiarthrodial
Definition
intervertebral discs
Term
Diarthrodial
Definition
knee, typical joints we think of
Term
Pannus
Definition
fibrovascular tissues arising from synovium and covering articular surface
Term
Fibrillation
Definition
degenerative joint disease
cartilage becomes frayed and fragmented
Term
Eburnation
Definition
rubbing down of articular cartilage to the point of exposed subchondral bone
Term
Arthritis
Definition
inflammation of joint and joint capsule
hematogenous direct penetration, extension
bacterial/spirochete or viral
trauma, immune mediated, laminitis
Term
Rheumatoid Arthritis
Definition
immune mediated arthritis
causes proliferative synovitis
Term
Laminitis
Definition
aka Founder
Changes in junciton between P3 and hoof wall
Seen in cattle and horses
Associatd with chagnes in diet (grain overload), toxin (black walnut)
Pathogenesis is not understood
Altered circulation to hoof wall
Ischemia and degeneration of laminae
Not suppurative lesion
Term
Type I Muscle Fibers
Definition
slow twitch
oxidative, aerobic red muscle
lots of mitochondria
fatique resistant
Term
Type II Muscle Fibers
Definition
fast twitch
glycolytic, anaerobic, white muscle
fatique sensitive
low mitochrondria
Term
Dystrophy
Definition
change in gene coding for dystrophin gene
Cytoskeletal protein membrane doesn't function properly which leads to degeneration and necrosis
Myonecrosis
Mineralization and necrosis of muscle fibers
White streaking of muscle fibers
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