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Bone
factors affecting bone synthesis and bone growth
11
Medical
08/26/2011

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Term
estogen
Definition
puberty increases what hormone that causes cessation of cartilage proliferation at the growth plate of long bones?
Term
osteopetrosis
Definition
generalized increase of bone mass, caused by congenital osteoclast hypofunction
Term
osteoporosis
Definition
Bone has less mass and is brittle because is no longer being remodeled, caused by immobalized/bedridden, lack of estogen
Term
vitamin D
Definition
decreased absorption of calcium by the intestine, so calcium-deficiency resulting in rickets or osteomalacia [adults]
Term
Vitamin A
Definition
deficiency in it suppresses endochondral growth of bone, leading to fragility or long bone fractures
Term
Vitamin C
Definition
deficiency in this prevents hydroxylation of proline and lysine, resulting in a weakened collagen fiber content and bone matrix that can't be calcified [scurvy]
Term
somatrotropin
Definition
This stimulates cartilage proliferation and bone growth, over secretion leads to gigantism [acromegaly]
Term
Thryoid Hormone
Definition
Absence or oversecretion during development/infancy leads to failure of bone growth or dwarfism
Term
estrogen
Definition
regulates growth rate, closes epiphyseal plate at puberty, decreased levels play a role in decreased bone deposited and decreased remodeling [osteoporosis] in later life.
Term
parathyroid hormone [PTH]
Definition
increases osteoclast activity to liberate calcium. Increased serum calcium levels
Term
Calcitonin
Definition
inhibits osteoclat activity, promotes calcium deposition in bone. lower serum calcium levels