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BME 111 Exam 1
Study guide based upon homework
89
Biology
Undergraduate 1
02/14/2011

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Term
What are the 4 major families of small molecules?
Definition
Sugars, nucleotides, amino acids, fatty acids
Term
What is the phosphodiester bond?
Definition
Bond between nucleotides
Term
What are some of the functions of nucleotides?
Definition
signaling molecules, storage and propagation of biological information, short-term energy storage
Term
What are some components of nucleotides?
Definition
The sugar ribose or deoxyribose, a nitrogenous base, a phosphate group
Term
Guanine forms 3 hydrogen bonds with...
Definition
cytosine
Term
The bond that forms in a condensation reaction between two nucleotides is termed a ...
Definition
phosphodiester bond
Term
Thymidine forms 2 hydrogen bonds with...
Definition
adenine
Term
Why is ATP so important?
Definition
Short term storage of energy
Term
True/False: DNA can be "printed" into precise patterns at a micron scale
Definition
True
Term
What is a peptide bond?
Definition
Covalent bond that attaches two amino acids together
Term
What are some of the components found in an amino acid?
Definition
an alpha-carbon, an amine group, a carboxyl group
Term
What are some properties that could be found in one of the R groups of amino acids?
Definition
negatively charged side chains, hydrophobic side chains, bulky ring structures
Term
The primary structure of the protein refers to its...
Definition
amino acid sequence
Term
The quarternary structure of the protein refers to its...
Definition
association with other proteins in order to be functional
Term
An alpha-helix structure is found in proteins at what level of structure?
Definition
secondary
Term
What are some of the functions of proteins?
Definition
Signaling, mechanical work including motors, and working as enzymes
Term
Fatty acids...?
Definition
contain a carboxylic head group that is hydrophilic, contain a long carbon tail that is hydrophobic, can be bonded to glycerol to form a mono-, di-, or tri-glyceride
Term
What is an unsaturated fatty acid?
Definition
Fatty acids with a double bond
Term
What are triglycerides
Definition
A molecule in which three fatty acids are attached to glycerol
Term
The functions of lipids includ
Definition
building membrane bilayers, precursors for steroid hormones, long term energy storage in adipose tissue
Term
Plants that produce large amounts of fatty acids or triglyderides could be used to power biodiesel engines because
Definition
there is a great deal of energy stored in the carbon chains of fatty acids and triglycerides
Term
Jojoba plants may be a good source of fuel oil for use in Arizona...
Definition
because they grow better here than corn or soybeans, they produce more liters of oil for acre of land than cotton, corn, or soybeans, and because neither coconuts nor brazil nuts grow here
Term
Which of these biofuels has the highest volumetric energy density? (wood fuel, sunflower oil, methane, ethanol)
Definition
sunflower oil
Term
Crop with the highest yield of oil?
Definition
algae
Term
If one is designing a biodiesel production plant, one would want easy access to..
Definition
farmers growing crops with a high fat or oil content
Term
What is BioDiesel composed of?
Definition
Mono-alkyl esters of long chian fatty acids
Term
Biological building blocks include
Definition
amino acids
Term
Hydrogen bonds occur between
Definition
the negative region of a molecule and the slightly positive H attached to an oxygen or a nitrogen
Term
Van der Waals force
Definition
are interactions between electropositively and elctronegatively charged regions of molecules, and individually quite weak, require large numbers of such interactions to be useful
Term
Sugars contain
Definition
carbon, oxygen, and hydrogen
Term
Disaccharides form between 2 monosaccharides
Definition
by a condensation reaction with water also a product
Term
Long chains of sugar molecules are known as
Definition
polysaccharides
Term
Functions of sugars include
Definition
mechanical structures in plants and insects
Term
Examples of polysaccharides include
Definition
cellulose, glycogen, and starch
Term
Ethanol production as an alternative fuel
Definition
requires plants with a high mass percentage of mono- and polysaccharrides such as starch or cellulose, requires yeast, and also produces carbon dioxide and livestock feed from the yeast solids
Term
Biofuels
Definition
include forestry wastes and agricultural leftovers such as stover, include methane, include recently grown crops
Term
Starting materials for the production of cellulosic bioethanol could include
Definition
municipal solid wastes, forestry wastes such as sawdust, small branches and dead trees, and energy crops such as fast-growing trees and grasses
Term
What is the role of NADH and FADH2?
Definition
to transfer electrons
Term
Where are the proteins involved in electron transport (oxidative phosphorylation) found in a cell?
Definition
in the Inner Membranes of the mitochondria
Term
The proteins in the electron transport chain pump _________ across the inner membrane to form a concentration gradient between the matrix and the inner mitochondrial space
Definition
protons
Term
What is the functions of ATP synthase in the mitochondria?
Definition
Synthesize ATP
Term
Approximate number of ATP molecules in a cell at any one time?
Definition
10^9
Term
Complete oxidation of 1 glucose molecule produces approximately how many ATP molecules?
Definition
34
Term
How are sugars stored for future use in the muscles and liver?
Definition
glycogen
Term
Where are fatty acids stored?
Definition
Adipocytes
Term
Where does photosynthesis occur?
Definition
chloroplasts
Term
What is the net result of photosynthesis?
Definition
Glucose + O2
Term
How does photosynthesis use light?
Definition
Source of energy
Term
What do catalysts do?
Definition
Lower the activation energy of the reaction
Term
What is the active site of an enzyme?
Definition
The site where the substrate binds on an enzyme
Term
How can you inhibit an enzyme?
Definition
Denature the protein, add a competitive inhibitor, add a negative modulator molecule
Term
What are catabolic pathways?
Definition
Pathways of enzymes that breakdown food molecules
Term
Why do cells often couple reactions?
Definition
To use the energy released by one reaction in another reactions, to decrease entropy in the cell, to minimize the amount of energy lost as heat
Term
Glycolysis is the breakdown of what molecule?
Definition
glucose
Term
Glycolysis produces?
Definition
ATP, NADH, and Pyruvate
Term
What is the fate of the pyruvate molecules made during glycolysis?
Definition
Transported into mitochondria, react with coenzyme A (Hs-CoA) to form acetyl coenzyme A, contribute substrates to the Kreb's cycle
Term
What molecule does glycolysis start with?
Definition
glucose
Term
What is digestion?
Definition
Breakdown of macromolecules into monomers by enzymes
Term
Cells use energy to create...
Definition
order
Term
An endothermic reaction requires...
Definition
more energy
Term
Proteins can be better catalysts than inorganic catalysis because
Definition
they have greater specificity
Term
Enzymes, because they are proteins, require specific conditions of _______ and ________ in order to optimize their rate of reaction.
Definition
temperature/pH
Term
The mitochondria are cellular organelles with what structural features?
Definition
matrix, inner and other membranes, inner membranous space
Term
Which of these molecules is NOT a direct product of Kreb's cycle
Definition
ATP
Term
Pyruvate and NADH from glycolysis are transported into which region of the mitochondria?
Definition
matrix
Term
The reason for breathing in oxygen is to...
Definition
accept electrons from the electron transport chain
Term
The electron transport chain uses the energy from the electrons to...
Definition
transport protons across the inner membrane into the intermembranous space
Term
The increased concentration of H+ in the intermembranous space of the mitochondria as compared to the matrix creates __________ across the inner mitochondrial membrane.
Definition
potential energy
Term
ATP synthase
Definition
is a 10nm rotary motor, has binding sites for ADP and Pi, converts the potential energy stored in the proton gradient into chemical bond energy
Term
The process of energy production in yeast under anaerobic conditions is known as...
Definition
Fermentation
Term
Lactic Acid is
Definition
a product of anaerobic metabolism in muscle
Term
A biological material
Definition
materials created by living organisms
Term
A defining feature of a biological material...
Definition
self-assembly, hierarchical structure, multifunctionality, self healing
Term
Classification terms for biological materials are...
Definition
ceramics and ceramic composites, polymers and polymer composites, elastomers, and cellular (porous) materials
Term
Stress is
Definition
force divided by cross-sectional area
Term
Strain is
Definition
the change in length after testing divided by the original length
Term
One measures stiffness (elasticity)...
Definition
stress/strain (initial segment of graph)
Term
The maximum amount of stress a material can handle is its
Definition
ultimate strength
Term
When stretching a material one does work on the material. As the material is released, energy is released. The difference between the work that comes out relative to that which goes in is termed a material's...
Definition
resilience
Term
In order to break a material, a certain amount of work per unit cross-sectional area (J/m^2) is applied. This is called the...
Definition
work of fracture
Term
After compression is applied, the decrease in length in the Y axis over the increase in width (in the X axis) determines a material's...
Definition
Poisson's ratio
Term
What are some of the advantages of materials with J-shaped stress strain curves?
Definition
Getting stiffer as the failure point approaches, increased safety factor, reduced area under the curve meaning less work need be done to stretch the material
Term
Organic matrices impact biomineralization through...
Definition
Stabilization of intermediate semicrystaline structures, and influencing the shape of mineral crystal formation
Term
In order to inhibit cracking in the devise you are designing, you might consider choosing a material that...
Definition
doesn't develop sharp tips on any cracks that they do suffer, using foamy materials whose "holes" will inhibit crack propagation, and using materials that have layered sheets oriented in different directions
Term
Toughness is bone _______ with increasing mineral volume fracture.
Definition
decrease
Term
A mechanism that contributes to the fracture toughness of bone...
Definition
uncracked ligament bridging, crack deflection, collagen fibril bridging, and constrained microcracking
Term
Tuning in biomaterials refers to
Definition
the alignment by natural selection of the properties of materials with their applications in an organism
Term
Markings on insects and spiders could be useful in low light situations and thus could be constructed of _______ materials
Definition
UV and fluorescent
Term
The fundamental adhesive force in gecko feet
Definition
Van der Waals forces
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