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Blood
Chapter 11
157
Anatomy
Not Applicable
07/26/2013

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Term
two of the body's most important functions
Definition
protection, transportation
Term
systems that provide protection and transportation
Definition
circulatory, lymphatic
Term
primary transportation fluid
Definition
blood
Term
not only performs vital pickup and delivery services, but also provides much of the protection necessary to withstand foreign "invaders"
Definition
blood
Term
a fluid tissue that has many kinds of chemicals dissolved in it and millions upon millions of cells floating in it
Definition
blood
Term
liquid portion of blood
Definition
plasma
Term
system that supplies transportation for cells of the body
Definition
circulatory
Term
system that plays a critical role in the functioning of the immune system, moves fluids and large molecules from the tissue spaces and fat-related nutrients from the digestive system to the blood
Definition
lymphatic
Term
________ ___________ of blood are many different types of cells and cell fragments taht are suspended in the plasma
Definition
formed elements
Term
the formed elements include:
Definition
RBC's, WBC's, and platelets
Term
the function of the _______ is to carry substances from on part of the body to another
Definition
blood
Term
many transported materials are dissolved in __________, so the composition of it varies based on what is going on in the body
Definition
plasma
Term
plays an important role in a number of systems, such as respiratory, digestive, urinary, and immune systems
Definition
blood
Term
prefix "pro-" and suffix "-ogen" indicate a(n) (ACTIVE/INACTIVE) substance
Definition
inactive
Term
___________ is the blood minus its formed elements and consists of water and many substances dissolved in it
Definition
plasma
Term
all of the chemicals needed by cells to stay alive are brought to them by the _____
Definition
blood
Term
most of the oxygen in the blood is carried in RBC's as
Definition
oxyhemoglobin
Term
the most abundant type of solute in the plasma is a group of ______ _________
Definition
plasma proteins
Term
any of several proteins normally found in the plasma; includes albumins, globulins, and fibrinogens
Definition
plasma proteins
Term
help thicken and maintain the blood volume
Definition
albumins
Term
include the antibodies that help protect us from infections
Definition
globulins
Term
neccessary for blood clotting
Definition
fibrinogen
Term
plasma minus its clotting factors; still contains antibodies
Definition
serum
Term
obtained from whole blood by allowing it to clot in the bottom of a tube and then pouring off the liquid substance.
Definition
serum
Term
a big person has (MORE/LESS) blood than a small person
Definition
more
Term
a man has (MORE/LESS) blood than a woman
Definition
more
Term
most adults probably have between ___-___ liters of blood
Definition
4-6
Term
blood normally accounts for about ___-___ % of total body weight
Definition
7-9
Term
the volume of the _______ part of blood is usally a little more than half the volume of whole blood
Definition
plasma
Term
normal plasma volume
Definition
2.6L
Term
normal blood cells
Definition
2.4L
Term
normal total blood
Definition
5 L
Term
three main types of formed elements:
Definition
RBC's, WBC's, and Platelets
Term
Red Blood Cell
Definition
erythrocyte
Term
White Blood Cell
Definition
Leukocyte
Term
platelet
Definition
thrombocyte; plays role in blood clotting
Term
______ leukocytes have granules in their cytoplasm
Definition
granular
Term
_________ leukocytes do not have granules in their cytoplasm
Definition
nongranular
Term
3 kinds of granular leukocytes
Definition
neutrophils, eosinophils, and basophils
Term
2 kinds of nongranular leukocytes
Definition
lymphocytes, monocytes
Term
RBC'S in one drop of blood
Definition
5 million
Term
WBC's in one drop of blood
Definition
7500
Term
platelets in one drop of blood
Definition
300 thousand
Term
two kinds of connective tissue that make blood cells for the body
Definition
myeloid tissue, lypmhatic tissue
Term
better known as red bone marrow
Definition
myeloid tissue
Term
forms rbc's
Definition
myeloid tissue (Red bone marrow)
Term
3 places red bone marrow is chiefly found in the adult
Definition
sternum, ribs, hipbones
Term
forms all types of blood cells except some lymphocytes and monocytes
Definition
red bone marrow
Term
located chiefly on the lymph nodes, thymus, and spleen
Definition
lymphatic tissue
Term
forms some lymphocytes and monocytes that red bone marrow cannot form
Definition
lymphatic tissue
Term
circulate for up to 4 months before they break apart and their components are removed from the bloodstream by the spleen and liver
Definition
erythrocytes (rbc's)
Term
________ leukocytes often have a lifespan of only a few days
Definition
granular
Term
__________ leukocytes may live for more than 6 months
Definition
nongranular
Term
mature __________ have no nucleus
Definition
RBC's
Term
describe the shape of the rbc
Definition
"caved in" on both sides so that each one has a thin center and thicker edges
Term
rbc total surface area is (ENORMUS/TINY)
Definition
ENORMUS
Term
functions of RBC's
Definition
1. transport carbondioxide out of cells and into lungs for disposal
2. transport oxygen from the lungs to other cells in the body
Term
harmful waste produced by the energy-producing processes of all living cells; must be carried away from cells and to the lungs for disposal into the external environment
Definition
carbon dioxide
Term
red pigment; iron containing protein in red blood cells
Definition
hemoglobin
Term
oxygen and hemoglobin unite to form
Definition
oxyhemoglobin
Term
_________ makes possible the efficient transport of large quantities of oxygen to body cells
Definition
oxyhemoglobin
Term
the compound formed by the union of carbon dioxide with hemoglobin
Definition
carbaminohemoglobin
Term
deficient number of red blood cells or deficient hemoglobin; caused by an inability of the blood to carry sufficient oxygen to the body cells
Definition
anemia
Term
can occur if the hemoglobin in RBC's is inadequate, even if adequate numbers of RBCs are present
Definition
anemia
Term
results from a decrease in number of RBCs caused by hemorrhage; characterized by low oxygen carrying capacity of blood; decreased RBC lifespan and/or increased rate of RBC destruction; ie bleeding ulcers
Definition
hemorrhagic anemia
Term
blood disorder characterized by a low RBC count; caused by destruction of myeloid tissue in the bone marrow; ofeten related to exposure to certain toxic chemicals, high-dose irradiation, certain drugs, and chemotherapy agents
Definition
aplastic anemia
Term
deficiency of RBCs resulting from a lack of vitamin B12' results from a failure of the stomach lining to produce intrinsic factor
Definition
pernicious anemia
Term
the substance that allows vitamin b12 to be absorbed from foods we eat
Definition
intrinsic factor
Term
severe, possibly fatal hereditary disease caused by an abnormal type of hemoglobin
Definition
sickle cell anemia
Term
when only one defective gene is inherited and only a small amount of hemoglobin that is less soluble than usual is produced; forms solid crystals when the blood oxygen is low, causing distortion of the RBC
Definition
sickle cell trait
Term
if ____ defective genes are inherited more of the defective hemoglobin is produced and the distorition of RBCs becomes severe
Definition
2
Term
condition in which there are inadequate levels of iron in the diet so that less hemoglobin is produced; results in extreme fatigue
Definition
iron deficiency anemia
Term
less hemoglobin, less oxygen transported to cells =
Definition
slower breakdown and use of nutrients by cells, less energy produced by cells, decreased cellular functions
Term
an excessive number of RBCs; blood is too thick to flow properly
Definition
polycythemia
Term
volume percent of blood cells in whole blood;
Definition
hematocrit Hct
Term
normally, about ____% of the blood volume consists of RBCs
Definition
45
Term
_____ values tend to be higher in man than women and decrease with age
Definition
hematocrit
Term
thin layer of WBCs and platelets located between the RBCs and plasma in a centrifuged sample of blood
Definition
buffy coat
Term
for a patient with anemia, the percentage of RBCs (DECREASES/INCREASES)
Definition
DECREASES
Term
for a patient with polycythemia, the percentage of RBCs (DECREASES/INCREASES)
Definition
increases
Term
excessive loss of body water; the most common fluid imbalance; an abnormally low volume of one or more body fluids
Definition
dehydration
Term
in ____________ blood volume is decreased and RBCs mae up a greater proportion of the total, although their actual numbers have not increased.
Definition
dehydration
Term
leukocytes are categorized by the presence of ______
Definition
granules
Term
white blood cell that stains readily with neutral dyes
Definition
neutrophil
Term
white blood cell that is readily stained by eosin
Definition
eosinophil
Term
wbc that stains readily with basic dyes
Definition
basophil
Term
type of WBC; B cells and T cells
Definition
lymphocyte
Term
phagocyte
Definition
monocyte
Term
defend the body from cancer cells that form inside our tissues and from microorganisms that have succeeded in invading our body
Definition
WBC Function
Term
total number of WBCs per cubic mL of blood
Definition
total WBC count
Term
total wbc count ranges between ____ and______
Definition
5000-9000
Term
proportion of each type of WBC reported as a percentage of the total WBC count; reveals more information than simply counting the total number of all the different types of WBCs in a blood sample
Definition
differential WBC count
Term
abnormally low WBC numbers in the blood
Definition
leukopenia
Term
disease in which the HIV virus attacks the T cells, there by compromising the boy's immune system
Definition
AIDS (acquired immunodeficiency syndrome)
Term
refers to an abnormally high WBC count; more common
Definition
leukocytosis
Term
most numerous of the active WBCs; protect the bdy from invading microorganisms by actually taking them into their own cell bodies and digesting them
Definition
neutrophils
Term
WBC that engulfs microbes and digests them
Definition
phagocyte
Term
serve as weak phagocytes; involves protection agains infection caused by certain parasites; involved in allergic reactions
Definition
eosinophils
Term
secrete the chemical histamine in peripheral blood; produce heparin
Definition
basophils
Term
released during inflammatory reactions
Definition
histamine
Term
helps prevent blood from clotting as it flows through the blood vessels of the body; obtained from the liver
Definition
heparin
Term
largest leukocytes; aggressive phagocytes; capable of engulfing larger bacterial organisms and cancerous cells
Definition
monocytes
Term
"large eater"; are specialized monocytes that have grown several times their original size after migrating out of the blood stream
Definition
macrophages
Term
Help protect us against infections, type of whit blood cell : b cell and t cell
Definition
Lymphocyte
Term
The complex process that makes us immune to infectious diseases
Definition
Immune mechanism
Term
Do not secrete antibodies but instead protect us by directly attacking bacteria or cancerous cells ; critical to the function of the immune system ;produce cell mediated immunity
Definition
T lymphocytes
Term
Secrete chemical compounds called antibodies that specifically act to destroy particular bacteria viruses or chemicals ; develop into plasma cells;
Definition
B cell (lymphocyte)
Term
Two kinds of lymphocytes
Definition
B cells and t cells
Term
Blood cancer characterized by an increase in WBCs ; can be acute or chronic, or lymphocytic or myeloid
Definition
Leukemia
Term
_______ and _______ leukemia are based on how quickly symptoms appear after the disease occurs
Definition
Chronic and acute
Term
_______ and ______ leukemia depend on on the cell type involved
Definition
Lymphocytic ans myeloid
Term
Play an essential role in blood clogging
Definition
Platelets
Term
Plugs up a torn or cut vessel and stops bleeding that otherwise might prove fatal
Definition
Clot
Term
How a ______ _______ forms :
Injury to blood vessel, prothrombin activatior forms, platelets become sticky, form a platelet plug, prothrombin converts to thrombin, thrombin reacts with fibrinogen which forms fibrin which seals the damaged vessel
Definition
Blood clot
Term
A protein formed by clogging factors from damaged tissue cells and platelets; it converts prothrombin into thrombin, a step essential in forming blood clots
Definition
Prothrombin activator
Term
Soft temporary accumulation near the opening of a broken blood vessel
Definition
Platelet plug
Term
Proteins present in normal blood that is required for blood clotting.
Definition
Prothrombin and thrombin
Term
Soluble blood protein that is converted into insoluble fibrin during clogging. (Normal plasma protein)
Definition
Fibrinogen
Term
Fibrous gel, insoluble protein in clotted blood
Definition
Fibrin
Term
Looks like a tangle of fine threads with RBCs caught in the tangle; the bloodclot that forms a more long term seal of the damaged blood vessel
Definition
Fibrin
Term
Acts by inhibiting the synthesis of prothrombin and other vitamin k dependent factors
Definition
Coumadin
Term
Used to prevent excessive blood clotting. Inhibited conversion of prothrombin to thrombin, thus preventing formation of a thrombus
Definition
Heparin
Term
Often used to regulate dosage of anticoagulant drugs. I. This test, thrombroplastin and calcium are added simultaneously to a tube of the patients plasma and a tube containing a normal control solution to determine time required fir clot formation
Definition
Prothrombin time
Term
The most used low dose anticiagulant
Definition
Aspirin
Term
Mathematical calculation reported as a number (normal.0.8-1.2) used to standardize the results of anticoagulantion testing
Definition
INR international normalized ratio
Term
Stimulates liver cells to increase synthesis of prothrombin. Faster clot formation
Definition
Vitamin k
Term
Stationary blood clot
Definition
Thrombus
Term
Formation of a blood clot in a blood vessel. Stationary
Definition
Thrombosis
Term
A blood clot or other substance (bubble of air) that is moving in the blood and may block a blood vessel
Definition
Embolus
Term
Obstruction of a blood vessel by a foreign matter carried in the bloodstream
Definition
Embolism
Term
Drugs that dissolve blood clots
Definition
Streptokinase
Recombinant tissue plasminogen activator (t-pa)
Term
Substance that when introduced to the body causes the formation of antibodies against it ; can activate the immune system to make certain responses ;including the production of antibodies
Definition
Antigens
Term
Almost all substances that act as antigens and stimulate the immune system are foreign protein s called ______ ______ antigens. That is, they are not the body's own natural self antigens, which are found on the cell membranes of normal body cells. Generally proteins that have entered the body from the outside by way of infection, transfusion, or some other method
Definition
Non - self
Term
Substance produced by the body that destroys or inactivates a specific substance (antigens) that has entered the body
Definition
Antibody
Term
Antibodies causing antigens to clump together
Definition
Agglutinate
Term
4 blood types
Definition
A b ab o
Term
Type A
Definition
A antigen
B Antibody
Term
Type b
Definition
B antigens
A Antibody
Term
Ab blood
Definition
A and b antigens
No antibodies
Universal receiver
Term
Type o
Definition
No antigens
a and b antibodies
Universal donor
Term
Antibody
Definition
Gives blood
Term
Antigens
Definition
Receive blood
Term
Red blood cells that do contain Rh factor antigens
Definition
Rh positive
Term
Rbc that doesn't contain Rh factor
Definition
Rh negative
Term
Injection. Of a special protein given to an Rh negative woman who is pregnant to prevent her body from forming anti Rh antibodies which may harm an Rh positive baby in a subsequent pregnancy
Definition
Rhogam
Term
the term ___ is used because this important blood cell antigen was first discovered in the blood of Rhesus monkeys
Definition
RH
Term
harmful effects or even death can result from a __________ ___________ reaction if the donor's RBCs become agglutinated by antibodies in the recipient's plasma
Definition
blood transfusion
Term
universal donor blood
Definition
type O -
Term
universal recipient blood
Definition
type AB +
Term
reinfusing of RBCs (or drugs that increase RBC production) into an athlete prior to competition in attempt to increase performance levels or stamina by increasing the oxygen-carrying capability of the blood
Definition
blood doping
Term
__________ never naturally contains anti-Rh antibodies
Definition
plasma
Term
disease that may develop when an Rh-negative mother has anti-Rh antibodies and gives birth to an Rh-positive baby and antibodies react with the Rh-positive cells of the baby
Definition
erythroblastosis fetalis
Term
one of the primary benefits of ______ ______ is an increase in the oxygen-carrying capacity caused by increases in hemoglobin levels
Definition
blood transfusion
Term
blood minus its cells
Definition
plasma
Term
RBC RANGE
Definition
4.5-5 MILLION
Term
WBC RANGE
Definition
5-10,000
Term
PLATELET RANGE
Definition
300,000
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