Term
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Definition
| Study of blood and blood-forming tissues |
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Term
| What are the blood-forming tissues? |
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Definition
Bone marrow
Blood
Spleen
Lymph system |
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Term
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Definition
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Term
| Where does hematopoiesis occur? |
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Definition
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Term
| Where do RBC, WBC, and platelets come from? |
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Definition
Immature blood cell
Stem cell |
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Term
| What do stem cells produce? |
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Definition
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Term
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Definition
| Soft material that fills the soft core of the bones |
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Term
| What are the two types of bone marrow? |
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Definition
Yellow: adipose
Red: hematopoietic |
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Term
| What does hematopoietic bone marrow do? |
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Definition
Actively produce blood cells
Primarily found in the long bones |
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Term
| What are the functions of blood? |
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Definition
Transportation
Regulation
Protection |
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Term
| What does blood transport? |
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Definition
O2 from lungs to cells
Nutrients from GI tract to cells
Hormones from endocrine glands to cells
Metabolic waste from cells to lungs, liver, and kidneys |
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Term
| What does blood regulate? |
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Definition
Fluid and electrolyte balance
Acid-base balance
Body temperature |
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Term
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Definition
Combats invasion of pathogens and other foreign substances
Maintains homeostasis of blood coagulation |
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Term
| What are the two major components of blood? |
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Definition
Plasma (55%)
Blood cells (45%) |
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Term
| What is the normal lab range for WBCs |
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Definition
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Term
| What is the normal lab for RBC's |
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Definition
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Term
| What is the normal lab for platelets? |
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Definition
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Term
| What is the function of RBC's |
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Definition
Transportation of gases
Assistance in maintaining acid-base balace |
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Term
| What is the function of WBC's? |
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Definition
| Promote blood clotting in response to injury. |
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Term
| What is the function of platelets? |
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Definition
| Promote blood clotting in response to injury |
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Term
| What color do leukocytes appear when separated from blood? |
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Definition
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Term
| What are the two categories of leukocytes? |
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Definition
Granulocytes
Agranulocytes |
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Term
| What are the granulocytes? |
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Definition
Neutrophils
Easinophils
Basophils |
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Term
| What are the agranulocytes? |
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Definition
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Term
| What is the function of Neutrophils? |
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Definition
Phagocytosis
Early phase of inflammation |
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Term
| What is the function of eosionphils? |
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Definition
Reduced phagocytosis
Alergic response
Parasitic infections |
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Term
| What is the function of Basophils? |
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Definition
Inflammatory response
Allergic response |
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Term
| What are the functions of lymphocytes? |
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Definition
| Cellular, humoral immune response |
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Term
| What is the function of monocytes? |
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Definition
Phagocytosis
Cellular immune response |
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Term
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Definition
| Describes the blood clotting process |
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Term
| Normal blood clotting mechanisms... |
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Definition
| ...minimize blood loss after injury |
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Term
| What are the components of normal hemostasis? |
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Definition
Vascular response
Platelet plug formation
Plasma clotting factors
Lysis of clot |
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Term
| What is vascular response? |
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Definition
| Immediate local vasoconstrive response of injured blood vessels |
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Term
| How does vascular response work? |
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Definition
Reduces leakage of blood from the injured vessel by reduce vessel size
Vasoconstriction gives time for platelet response and plasma clotting factors to be triggered |
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Term
| How is platelet plug formation activiated? |
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Definition
| Exposure to the intestinal from the injured blood vessel |
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Term
| What is platelet stickiness called? |
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Definition
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Term
| Formation of clumps is termed |
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Definition
| aggeregation or aglunation |
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Term
| What do platelets facilitate? |
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Definition
| The reactions of the plasma clotting factors |
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Term
| What to plasma clotting factors form? |
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Definition
| A visible fibirin on the platelet plug |
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Term
| What are the two pathways that activate plasma clotting factors? |
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Definition
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Term
| What is causes lysis(breakdown) of clot? |
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Definition
| Anticoagulation which helps keep blood fluid |
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Term
| What are the 2 means of anticoagulation? |
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Definition
Antitrombins: interferes with thrombin
Fibrinolysis: process that results in the dissolution of the fibrin clot |
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Term
| Where is the spleen located? |
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Definition
| In the upper left quadrant of the abdomen |
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Term
| What are the 4 major functions of the spleen? |
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Definition
Hematropoietic
Filtration
Immunologic
Storage |
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Term
| What is the purpose of the lymph system? |
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Definition
| To carry fluid from the interstitial spaces to blood |
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Term
| What does the lymph system consist of? |
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Definition
Lymph fluid
Lymph capillaries
Lymph ducts
Lymph nodes |
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Term
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Definition
| The pale yellow interstitial fluid that has diffused through capillary walls |
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Term
| Where does lymph fluid circulate? |
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Definition
| Through special vasculature |
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Term
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Definition
| Too much interstitial fluid or reduced absorption |
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Term
| Lymphedema occurs as a complication of what? |
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Definition
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Term
| What are lymphatic capillaries? |
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Definition
| Thin-walled vessels with irregular diameter |
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Term
| What is the difference between lymphatic capillaries and blood capillaries? |
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Definition
| Lymphatic are larger but do not have valves |
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Term
Lymphatic capillaries from to create what?
What does that do? |
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Definition
| Lymphatic vessels that carry all lymph fluid to the ducts |
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Term
| What are the major lympatic ducts? |
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Definition
Right lymphatic duct
Thoracic duct |
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Term
| Where do the lymphatic ducts drain? |
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Definition
| Into the subclavian veins in the neck |
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Term
| What is the function of lymph nodes? |
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Definition
| Filtration of pathogens & foreing particles that are carried by the lymph to the nodes |
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Term
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Definition
| Small clumps of lymphatic tissue found in the groups along lymph vessels at various sites |
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Term
| How many lymph nodes are foudn through the body? |
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Definition
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Term
| What part of the body has the greatest promominence of lymph nodes? |
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Definition
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Term
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Definition
Acts as a filter
Produces all the procoaguatlion essentail to hemostasis and blood coagualtion
Stores excess iron
Produces hepcidin |
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Term
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Definition
| Key regulator of iron balance |
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Term
| What are some assessment questions to ask? |
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Definition
Smoke or drink
Hx of blood (in vomit, stool(black), urine)
N&V, anorexia, diet issues
Iron or folic acid deficiencies?
Tired, fatigued even after full rest
Join pain
Unsual brusing
Religious and ethical values |
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Term
| What are common hematologic labs? |
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Definition
CBC
ESR
Blood typing & Rh factor
Iron studies
Clotting studies |
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Term
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Definition
| Erythrocyte sedimenation rate: setteling of RBC: used to diagnosis inflammatory condition |
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Term
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Definition
Male range 1-15
Female range 1-20 |
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Term
| What are common radiologic studies? |
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Definition
CT
MRI
Bone marry examination
Lymph node biopsy
Molecular cytogentics & gene analysis |
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