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Block 6 Path Exam One
Histology for Path Exam One
33
Histology
Graduate
10/23/2012

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Cards

Term
cortex
Definition
outer surface just deep to connective tissue capsule
Term
renal columns
Definition
deeper extensions of cortex
Term
medulla
Definition
conical structures (pyramids) that are separated by renal columns
Term
minor calyx
Definition
funnels urine from pyramid into major calyx which then funnels urine into ureter
Term
renal pelvis
Definition
where major callyx funnel into ureter
Term
nephron
Definition
functional unit of kidney
Term
glomerulus
Definition
cluster of capillary tufts plus visceral epithelial covering through which blood is filtered
Term
capillary endothelial cells
Definition
simple squamous epithelial cells that form an imperfect sheet containing pores or fenestrations
Term
glomerular basement membrane
Definition
thick structure consisting of three lamina fused underlying connective tissue of capillary endothelium and visceral layer of bowmans capsule
Term
podocytes
Definition
epithelial cells with foot-like extensions that externally coat the glomerular capillaries making contact with the glomerular basement membrane
Term
mesangial cells
Definition
phagocytic cells often found in the kidney where blood vessels closely parallel each other. believed to be important in maintaining integrity of basement membrane by removing filration residues
Term
bowman's capsule
Definition
acts as a funnel to collect material that leaks out of glomerulus. composed of two facing layers of simple squamous epithelium.
Term
visceral layer of bowman's capsule
Definition
inner layer that lies adjacent to glomerulus. cells become podocytes.
Term
parietal layer of bowman's capsule
Definition
outer layer that is continuous with proximal convoluted tubule at the urinary pole
Term
urinary space
Definition
lies between visceral and parietal layers. continuous with lumne of PCT at the urinary pole.
Term
proximal convoluted tubule
Definition
extremely active in the process of reabsorption. lined by large simple cuboidal cells with spherical, cenrally located nucleus and a brushed border. abundant mitochondria so eosinophilic cytoplasm, esepecially at basal surface leading to striations. interdigitated lateral membranes so difficult to distinguish lateral cells boundaries.
Term
thin segment of loop of Henle
Definition
abrupt transition from PCT. cells consist of thick squamous epithelium with rounded nuclei that bulge into lumen. tend to be light staining.
Term
distal convoluted tubule
Definition
eosinophilic simple cuboidal cells with basal striations. smaller cells with more apical nuclei. lack a brushed border. cytoplasm not as eosinophilic.
Term
juxtaglomerular apparatus
Definition
function in blood pressure regulation.
Term
macula densa
Definition
flattened edge of DCT where cells are taller and more tightly packed
Term
JG cells
Definition
highly modified cells of the tunica media
Term
mesangial cells
Definition
form triangular wedge between blood vessels and DCT
Term
collecting tubules and collecting ducts
Definition
simple cuboidal cells with spherical, dark staining nuclei. become simple columnar as collecting ducts merge to form larger ducts
Term
principle cells
Definition
pale staining due to limited organelle. actively transport sodium and postassium. become predominant cell in the distal collecting ducts
Term
intercalated cells
Definition
stain more darkly due to more abundant organelles. more abundant luminal microvilli. actively transport protons and bicarb ions.
Term
papillary ducts of Bellini
Definition
collecting tubules and collecting ducts continue merging
Term
papilla
Definition
where epithelium changes to transitional
Term
renal corpuscle
Definition
glomerulus plus bowmans capsule - always in cortex
Term
loop of Henle
Definition
descends into medulla
Term
medullary nephrons
Definition
capable of forming more concentrated urine
Term
ureters
Definition
muscularis consists of inner longitudinal (spiral) and outer circular layers of smooth muscle. lining of transitional epithelium resting on top of a lamina propria that is rich in elastic fibers.
Term
bladder
Definition
wall structure very similar to ureter except that muscularis is thicker and fibers oriented in all directions
Term
female urethra
Definition
lined with transitional and stratified squamous epithelium
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