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Block 3 Pathology Exam One
Block 3 VCOM 2012
28
Pathology
Graduate
01/28/2012

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Term
Nissl Bodies
Definition
dark staining RER because it is actively making protein, only present in soma, not axon or axon hillock. aka chromatophilic substances
Term
neurofilaments
Definition
visible with silver or gold stains. maintain shape of cytoplasmic extensions
Term
dendrites
Definition
transmit impulses towards cell body. typically several and they are highly branched
Term
axon
Definition
long, typically nonbranchinb process that transmits impulses away from cell body
Term
synaptic bouton
Definition
enlarged terminal end of an axon. site of neurotransmitter release
Term
pseudounipolar
Definition
primary sensory neurons have this kind of shape
Term
myelination
Definition
allows impusle to travel up to 150X faster along an axon
Term
oligodendrocytes
Definition
myelinates several axons in the CNS
Term
Schwann cells
Definition
myelinates only one axon, but can ensheath several unmyelinated axons in PNS
Term
Nodes of Ranvier
Definition
myelinating cells are approx 1-2mm in length, which leaves gaps between myelin sheaths
Term
synapse
Definition
specialized cellular junction that allows communication between cells even though the participating cells are not in direct physical contact
Term
neurosecretory granule
Definition
contains neurotransmitter plus packaging and transport proteins. contents released into synaptic cleft upon stimulation of action potential
Term
glial cells
Definition
supporting cells of nervous system
Term
astrocytes
Definition
large star shaped cells. fibrous and protoplasmic types. form framework guide during fetal development. move fluid from extracellular spaces to blood vessels to maintain [ionic]. play role in BBB by forming end feet around blood vessles which creates a highly selective permeability. form scar when neurons are lost (Gliosis)
Term
ependyma
Definition
appear as ciliated simple cuboidal epithelial cells that line the ventricles and the central canal of the spinal cord.
Term
glia limitans
Definition
unique basement membrane via intertwining of ependymal cells and underlying astrocytes
Term
microglial cell
Definition
immune cells of CNS. phagocytosis.
Term
gray matter
Definition
unmyleinated fibers and nerve cell bodies
Term
neuropil
Definition
entanglements of nerce cell processes in CNS
Term
white matter
Definition
myelinated and unmyelinated tracts in CNS
Term
choroid plexus
Definition
lining of ventricles that produces CSF via selective filtration and supplementation. simple cuboidal epithelium overlying highly vascularized connective tissue
Term
endoneurium
Definition
surrounds individual axons/dendrites and any associated schwann cells
Term
perineurium
Definition
groups axons/dendrites into small bundles called fascicles
Term
epineurium
Definition
tough outer sheath that binds fasciles into a nerve
Term
ganglia
Definition
only sites where neuron cell bodies are located outside the CNS
Term
sensory ganglia
Definition
pseudounipolar neurons surrounded by a capsule composed of satellite cells
Term
sympathetic ganglia
Definition
multipolar neurons that lack capsule of satellite cells. cell bodies accumulate lipofuschin (rust colored wear and tear pigment) with age
Term
parasympathetic ganglia
Definition
small and embedded within wall of organ
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