Term
|
Definition
| persisten sadness, hopelessness, despair, disrupted sleep patterns, suicidal thoughts |
|
|
Term
| monamine oxidase inhibitors |
|
Definition
MAOs break down monoamines
MAOIs increase monamine activity at synapses |
|
|
Term
| selective serotonin reuptake inhibitors |
|
Definition
| block reuptake of serotonin |
|
|
Term
| how quickly do antidepressants work |
|
Definition
affect synaptic transmission acutely
2-6 weeks
neural chain |
|
|
Term
| secondary binding of antidepressants |
|
Definition
|
|
Term
|
Definition
|
|
Term
| gate control theory of pain |
|
Definition
opiates don't work directly at site of pain
descending info. from brain can 'gate' incoming pain signals in the spinal cord |
|
|
Term
|
Definition
euphoria
high abuse potential
narcotic
severe depedency |
|
|
Term
|
Definition
| causes withdrawal symptoms |
|
|
Term
|
Definition
produced in midbrain
two pathways |
|
|
Term
| mesolimbocortical pathway |
|
Definition
| reward, reinforcement, schizophrenia |
|
|
Term
|
Definition
|
|
Term
|
Definition
anything that causes release of DA is pleasurable
associated with: eating, sex, drugs of abuse
intracranial self-stimulation in rats |
|
|
Term
| intracranial self-stimulation (ICSS) |
|
Definition
drug self-administration
rats will press bar for drugs that increase DA activity
conditioned place preference |
|
|
Term
|
Definition
|
|
Term
|
Definition
chronic severe mental illness
loss of touch with reality, disordered thoughts, delusions, hallucainations (primarily auditory) |
|
|
Term
| evidence for DA hypothesis of schizophrenia |
|
Definition
classic anti-psychotic drugs are DA antagonist
overmedication of Parkinson's patients creates schizophrenic symptoms
tradition antipsychotics work well for positive symptoms
|
|
|
