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Biology of Aging exam 3
Exam 3 eyes, ears, muscle, and aging of nervous system
74
Biology
Undergraduate 3
11/06/2007

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Cards

Term
What is the Cornea?
Definition

-Its the transparent structure located behind the conjunctiva.

 

-It's thick and curved so it refracts light that passes through it.   

Term
Aging Corneas change how?
Definition

-not as Transparent

 

-Blue is blocked

 

-light gets scattered more, Glare- seeing bright areas in the wrong places.

 

-gets flatter so it can't refract light as well

 

-more difficult to see closer objects. 

    -Increase Astigmatism- irregular curvature of cornea.  Light doesn't get focused right.

 

-sensitivity to pain is diminish 

Term
What is the Pupil?
Definition

-Hole in the center of hte iris

 

-Allows light to enter rear region of eye.

 

-muscle cells in iris control size of pupil.  controlled by ANS

 

 

Term

What changes do aged Pupils have?

 

Definition

Strength of muscle cells decreses

 

-Collagen in iris get stiffer and thicker

 

-Size of pupil diminishes with each passing year.  Starts @ 20.

 

-can't react as fast to changing light. 

Term
Iris
Definition

Behind hte Cornea.  Shaped like a cd .

 

-gives eye color.

 

-controls size of pupil 

Term
Aged Iris:
Definition

not as strong.

 

collagen fibers are thicker and stiffer

 

can't react as fast 

Term
Lens?
Definition

Transparent

 

refract light alot.

 

very elastic.  

 

behind iris and pupil. 

Term
Changes in Lens with age?
Definition

Four of them:

1) Not as transparent.  Begins in 30's

 

2)Forming of Opacities-opaque spots in the periphery.  If formed in center of eyes then they're called Cataracts.  

 

3) Can't refract light well.

    Accumulation of damange proteins and formation of abnormal ones

 

4) Decrease in flexibility/elasticity

    accomodation increases.   

Term
After Light is refracted through lens where does it go through?
Definition
The Vitreous Humor!!
Term
What is this Vitreous Humor?
Definition

Liquid that fills the cavity in the eye behind the lens!

 

-composed of a soft gell.

 

makes an outward pressure on the eye.  makes hte curve.   

Term
Types of light sensors in the retina:
Definition

1) Rods - light

 

2) cones - color 

Term
What is the retina?
Definition

The thin layer that lines the rear portion of the inner cavity of hte eye. 

 

Consists of the Sensory Retina and the Pigmented epithelium 

Term
Cones:
Definition

sensitive to color

 

three types:

red, blue and green.

 

not very sensitive to light.

 

 

Term
Rods?
Definition

are very sensitive to light!

 

only see in black and white.

 

This is why in dark rooms you do not see any color.

 

 

Term
Age Changes in Rods:
Definition

Rods lengthen

 

get beint into irregular shapes

 

result is can't see as well in dim light. 

Term
Changes in Cones:
Definition

Beginning at 40 they decrese in lenght and in number.

 

gradual drop in ability to see in detail and in color. 

Term
What is part of the Optic media?
Definition

Conjunctiva

 

Cornea

 

Aqueous Humor

 

Lens

 

Vitreous Humor 

Term
Optic nerve
Definition
the nerve that transmits visual information from the retina to the brain.
Term
What is a Cataract?
Definition

Opacity that forms in the center of the lens.

 

Very cloudy and makes it hard to see.

 

Chemical changes in lens cause cloudiness

 

Limited visual acuity 

Term

Retinal degeneration

 

Definition

occurs when the flow of vitreous humor out of the eye becomes blocked

This leads to increased eye pressure.

leaves dark spots in field of view.

 

Term
Glaucoma
Definition

Optic nerve damage from pressure in eye blocking blood supply

 

Diabetes is a risk factor for glaucoma.

 

steals vision slowly and irreversably

 

air puff tests quick way to test for it 

Term
Aging effects on eye:
Definition

Cones shorten/lost   Rods lenghten/bend

 

Iris isn't as elastic/less light can enter eye

 

UV light causes lens yellowing

 

Cataracts

 

Lens isn't as elastic-poorer near vision

 

retinal degeneration

 

Glaucoma

 

Macular (central) degeneration-smoking risk factor

 

 Retinal detachment via trauma or diabetes mellitus

 

Term
Macular (Centra) degeneration
Definition

Occurs when central part of retina (macular) degenerates

 

Main cause of vision loss in elderly

 

Comes in two forms: Dry and Wet

 

Wet is rare and needs immediate medical attention

 

Smoking is a major risk factor 

Term
Path of light through eye
Definition
Cornea -> Pupil/iris -> lens -> Humor -> retina -> rods and cones -> optic nerve -> brain
Term
Path of sound through ear
Definition
External ear-> ear canal ->ear drum ->Ossicles ->Mechanoreceptors -> cochlea -> vestibulo-cochlear nerve ->brain
Term
External Ear
Definition

two parts:

Pinna- visible part

 

ear canal 

Term
Eardrum
Definition

thin flexible membrane covering the inner end of the ear canal

 

vibrated by sound passing through ear canal 

Term
Ossicles
Definition

tiny bones in the middle ear:

1)Hammer (malleus)

2)Anvil (incus)

3)Strirrup (stapes) 

Term
Mechanoreceptors
Definition

specalized organs that relay information to nervous system

 

associated with hair cells in the cochlea 

Term
Cochlea
Definition

Snail shape structure inside inner ear

 

contains Organ of Corti 

Term
Vibrations of the ear drum vibrates a series of tiny bones called ____________.
Definition
Ossicles!
Term

Vibration of ossicles initiates pulse waves that stimulate ____________ associated with hair cells in the ___________.

 

Definition
mechanoreceptors, Cochlea.
Term
The Mechanoreceptors convert the mechanical impulse into an ____________ that is transmitted via the ______________ ______ to the brain where it is interpreted.
Definition
electrical impulse, vestibulo-cochlear nerve.
Term
Vestibulo-cochlear nerve
Definition
responsible for transmitting equilibrium and auditory info to brain
Term

Eustachian tubes

 

Definition

equilibrate pressure

 

mucus drainage 

Term
Semicircular canals
Definition

provide orientation input through vestibular nerve

 

sense movement and position of fluid in the canals

 

very important for balance.

 

detect motion in 3d 

Term
Organ of Corti
Definition

found in cochlea

 

important for auditory

 

contains hair cells 

Term
effects of aging on ear:
Definition

Presbycusis-can't hear as well

 

loss of spatial orientation-dizziness

 

ear drum thicker and less sensitive

 

can't hear high pitch noises

 

impairment in speech processing -can't be helped by hearing aids

 

Tinnitus

 

earwax gets sticker and plugs ears 

Term

Presbycusis

 

Definition

decreased ability to hear

 

affects 40% of those over 75 years old; more in men

 

cumulative damage from loud noises

 

leads to problems responding to loud sounds

 

can be helped with hearing aids 

Term
Tinnitus
Definition

perception of sounds not present (ringing)

 

several causes:

obstructions, infections, neural disfunction 

Term
Functions of Muscular system:
Definition

moving organism parts (locomotion and manipulation)

 

Moving substances from place to place (swallowing-pooping, blood pumping, gland excretion, breathing, birthing)

 

structural integrity,

 

hair raising

 

eye movement

 

body language

 

vocal language

 

dan's mom 

Term
Three typees of muscle tissue:
Definition

1) Cardiac Muscle

 

2) Smooth Muscle

 

3)Skeletal Muscle 

 

Term
Cardiac Muscle
Definition

found in heart

 

striated 

Term
Smooth Muscle
Definition

found within organs in many body systems

 

Ex: Susan's vagina 

Term
Skeletal Muscle
Definition

moves the body

 

attached to bones

 

more than 600 muscles 

Term
Muscles __________  _______ (energy consuming) to cause movement than ________ _________ to return to resting position.
Definition
actively contract, passively extend
Term
Muscles depend on ______, __________, and ________ ________for inputs.
Definition
nervous, circulatory, and respiratory systems
Term
Muscles also depend upon _________, _____________, and ____ for structural support.
Definition
Collagen, elastin, and fat
Term
Muscles are made of multiple _________ ______ (cells) that are made up of varying numbers of ___________ which in turn are made up of multiple _______________.
Definition
Muscle fibers, myofibrils, myofilaments
Term
muscles are connected (anchored) to the bones through __________ made of _________.
Definition
tendons, collagen
Term
Contraction is initiated by release of ___________ from the motor neuron axon.
Definition
neurotransmitter
Term
The Neurotransmitter than binds to the _____________ ___________ (sarcolemma)
Definition
plasma membrane
Term

Sarcolemma spreads impulse through cell via the _________ to the _________ ________.

 

Definition
T-tubules, Sarcoplasmic Reticulum
Term
The Sarcoplasmic reticulum releases ______ to the myofibirls activating ____ ________ and  _________ ________.
Definition
Calcium, ATP breakdown, and Muscle contraction
Term
the Sarcolemma is?
Definition
the muscle cell membrane
Term
sarcoplasmic reticulum
Definition

the membrane of the endoplasmic reticulum within muscle cells are arranged in the form of lacy tubes that extend over the length of hte cell.

 

regulate the movement of calcium ions needed for contraction 

Term
Myofilaments are made of either _______ or __________ in alternating arrays.
Definition
Actin (thin), Myosin (thick)
Term
Aging of muscle changes
Definition
Term
Activation of muscles is impaired due to defects in fine structure of _________ and _________.
Definition
neurons and sarcolemma.
Term
This impaired muscle activation leads to ____________ and there fore a ________ ________.
Definition
discoordination and weaker respons.
Term
what leads to the death of a muscle cell?
Definition
reduction of muscle inervation.
Term
death of muscle cells is the largest component of _______ ____.
Definition
muscle thinning
Term
what happens when muscle circulation is reduced?
Definition
theres more anaerobic use and muscle damage
Term
inactivity and aging lead to decreases in
Definition

1) cellular ATP

 

2)creatine phosphate and glycogen

 

3) sarcomeres

 

4) Mitochondria

 

5) overall cell thickness 

Term
Significante ____________  _________ affect the ability to make and maintaind muscle.
Definition
hormonal changes.
Term
Insulin like Growth factor 1 (IGF-1) did what?
Definition
gene increases muscle mass in lab animals
Term
What three substances help increase muscle mass but at a cost
Definition

Growth hormone

 

Testosterone

 

DHEA 

Term
Serious loss of muscle mass is called ____________.
Definition
Sarcopenia
Term
Loss of strenght is _____ in those that use muscles and ______ in those who do not.
Definition
slow, fast.
Term
diet must contain sufficient ________ to maintain muscle mass.
Definition
protein.
Term
Indirect causes of Sarcopenia
Definition
Illness, medication, and joint pain.
Term
With age, ____________ ________ increases and ________ __ __________ decreases.
Definition
reaction time, speed of movement.
Term
There is significant reduction in __________, and ___________ time and _______ max.
Definition
stamina, recovery time, and VO2
Term
accumulation of fat in muscle is linked with ____-________ _________.
Definition
late-onset diabetes.
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