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Biology Ch. 4 - Nervous System
MCAT
16
Biology
Undergraduate 1
04/05/2016

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Term
What cells produce the myelin sheath?
Definition

oligodendrocytes in the CNS

Schwann cells in the PNS

Term
What is a ganglia?
Definition
a cluster of neuron cell bodies
Term
What is the function of astrocytes?
Definition
nourish neurons and form blood-brain barrier
Term
What do ependymal cells do?
Definition
produce cerebrospinal fluid which physically supports the brain
Term
what do microglia do?
Definition
phagocytes of the CNS
Term
How does the Na+/K+ ATPase function?
Definition
It uses ATP to maintain resting membrane potential by moving 3 Na+ ions out of the cell for every 2 K+ ions into the cell. Inside of the cells is more negative.
Term
Why is the inside of the cell more negative than the outside?
Definition
The cell membrane is more permeable to potassium ions and because they have a higher concentration in the cell they will move down their gradient out of the cell. Becuase potassium is positively charged and leaving the cell it results in a more negative interior.
Term
What is summation in regard to action potentials? What kinds are there?
Definition
It is the additive effect of multiple signals. Temporal summation is multiple signals occuring close to each other in time. Spatial summation has additive effects based on the number and location of incoming signals.
Term
What happens when the threshold is reached?
Definition
Voltage gated sodium channels open in the membrane allowing sodium ions to rush in down their electrochemical gradient into the cell making the cell more positive. This depolarizes the membrane. Sodium channells will become inactivated (deinactivation only occurs at resting potential). Potassium channels now open and potassium rushes out of the cell down its electrochemical gradient causing the cells to repolarize and even hyperpolarize causing a refractory period.
Term
What are the two kinds of refractory periods?
Definition

Absolute - no amount of stimluation can cause another action potential

 

Relative - greater than normal stimulation can cause an action potential

 

Term
How does an action potential propogate down the axon?
Definition
The axon hillock depolarizes causing the surrounding area to depolarize as well and this causes a chain reaction all the way down the axon.
Term
What happens when the action potential reaches the nerve terminal?
Definition
The depolarization causes voltage-gated calcium channels to open. The influx of calcium triggers fusion of the membrane-bound vesicles with the cell membrane which causes exocytosis of neurotransmitter.
Term
white matter vs grey matter
Definition
white matter is myelinated and grey matter is not
Term
Where do sensory and motor neurons enter and leave the spinal cord, respectively?
Definition

Sensory neurons enter dorsally and their cell bodies are found at the dorsal root ganglion.

Motor neurons leave ventrally. They synapse within the spine.

Term
What is a primary difference between autonomic and somatic nervous system regarding number of neurons utilized?
Definition
The autonomic nervous system uses two neurons, pre- and postganglionic, to communicate to the peripheral nervous system. The pre neuron's soma (cell body) is found in the CNS and its axon travels to the post neuron in the PNS which then affects target tissue. The peripheral motor neurons go straight from the spinal cord to the muscle without synapsing.
Term
What are the two kinds of reflex arcs and how do they work?
Definition
Reflex arcs are neural circuits that control reflexive behavior. Monosynaptic reflex arc has only a sensory neuron that synapses with a motor neuron. A polysynaptic reflex arc has at least one interneuron between the sensory and motor neurons.
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