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Biology 20 - Blood and Immunity
Sewell 20 - 1
56
Biology
11th Grade
03/30/2011

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Term
Blood is classified as a type of tissue, even though it's a ______
Definition
Fluid
Term
What is a tissue?
Definition
Any group of cells that have similar STRUCTURES and carry similar FUNCTIONS
Term
6 TASKS BLOOD DOES
Definition
- Maintains H2O Balance
- Maintains pH Balance
- Maintains Body Temperature
- Transports nutrients, wastes, gases ( RBC = oxygen and carbon dioxide exchange)
- Transport WBC'S
- Transports platelets
Term
What 2 parts is blood composed of?
Definition
Cellular and Non-Cellular
Term
What is cellular part of blood composed of? (3)
Definition
Red Blood Cells, White Blood cells, and Platelets
Term
Cellular component of blood is how much percent?
Definition
45%
Term
What is the non-cellular component of blood made out of? (1)
Definition
Plasma
Term
How much percent is the non-cellular component of blood ?
Definition
55%
Term
The average body contains how much L's of blood?
Definition
5 L.
Term
A drop of blood consists of?
( 1, 1, 1, 2)
Definition
Platelets
Plasma
WBC'S (Lymphocytes, Phagocytes)
RBC'S
Term
Scientific names for red blood cells, white blood cells, and platelets?
Definition
Erythrocytes, Leukocytes, and Thrombocytes
Term
Out of the 3 components of blood, which one is red, and which are colorless?
Definition
Red Blood Cells are RED, WBC'S AND PLATELETS are colorless.
Term
Where do all the components come from? Source?
Definition
Bone Marrow
Term
Put RBC, WBC, and platelets in largest to smallest size.
Definition
Platelets, RBC, WBC
Term
Direction of flow of RBC'S, WBC'S, AND PLATELETS.
Definition
Red Blood Cells - with the direction of blood
WBC'S AND PLATELETS - any direction
Term
What is erythropoisis?
Definition
Production of Red Blood Cells.
Term
3 things that increase erythropoisis.
Definition
Hemorrhage, exercise, high altitude
Term
Describe Centrifugation. What's the machine's name?
Definition
(Machine = centrifuge)
Spinning of mixed contents to separate into density specific layers.
Term
What is a Hematocrit, and how does it look when a normal one is compared to an abnormal one?
Definition
An abnormal hematocrit will have a larger percentage of platelets than normal.
Term
What's the job of a hemoglobin?
Definition
It carries oxygen to the tissues and carbon dioxide away from the tissues.
Term
What is a hemoglobin?
Definition
A special protein that carries oxygen.
Term
From hemoglobin, what part is the protein part, and what part is the prosthetic part?
Definition
Globin - protein
Heme - prosthetic
Term
What is HEME able to combine with, and what are the names one they combine with them? (4)
Definition
Oxyhemoglobin - oxygen
Carbamino - Carbon dioxide
Hemoglobinic Acid - H +
Term
2 components of Hemoglobin
Definition
Polypeptide Chain (Globin) - Alpha or Beta
Iron Based Pigment (Heme)
Term
What appearance do RBC's have, and explain why they don't have a nucleus.
Definition
They have a punched appearance, since they don't have a nucleus. You can say they're enucleated, since they lose their nucleus to hold hemoglobin's.
Term
Life span of a RBC?
Definition
ABOUT 120 DAYS.
Term
How do RBC'S release hemoglobin into the blood plasma?
Definition
They end up breaking, and rupturing once they're cell membrane weakens.
Term
What kind of cells engulf the hemoglobin?
Definition
Kupffer cells.
Term
How do hemoglobin's break down into heme and globin?
Definition
By Kupffer cells.
Term
Difference between granulocytes and agranulocytes ?
Definition
Granulocytes contain granules in their cytoplasm while agranulocytes do not.
Term
3 types of Granulocytes?
Definition
Neutrophils, Eosinophils, and Basophils
Term
Jobs of :
Neutrophils, Eosinophils, and Basophils ?
Definition
Neutrophils - Phagocytically attacks in local tissue ONLY.
Eosinophils, and Basophils - Release histamines which atrract other WBC'S to an infected area.
Term
Types of Agranuolocytes? (2)& their jobs.
Definition
Monocytes( which can become macropahes) they phagocytically attack throughout the whole body. Not only in a specific area like Neutrophils.

Lymphocytes - antibody-mediated immunity - includes B & T CELLS.
Term
Histamine will cause ________ and increase _____ in the capillary.
Definition
Vasodilation , Bloodflow
Term
The action of squeezing out WBC'S?
Definition
Diapedesis
Term
2 Forms of Attack of leukocyes?
Definition
Phagocytic attack , Antibody-mediated attack
Term
Difference between phagocytic attack and an antibody-mediated one?
Definition
Phagocytic is carried out by macrophages and complementary proteins.(NON - SPECIFIC)
Antibody-mediated ones are carried about by T&B Cells, also known as lymphocytes. It's a specific defense,as they are only made to target ONE foreign invader
Term
How many parts consist of a phagocytic attack and the process?
Definition
1 Macrophage, and 3 Complementary Proteins (1, 2, 3)

1) Puts a coating
2) Dissolves the membrane, killing it.
3) Attracts Macrophage

Macrophage then eats the remains, and stores it's antigen information.
Term
Why is antibody mediated attacks used as a backup or 2nd option?
Definition
They are used when the body needs a larger defense system, as the phagocytic defense isn't as sufficient for large concentrations or that the foreign bodies are spreading too rapidly.
Term
Antibody Mediated Attack :
This is your ___________ defense against infection.
Definition
Long term.
Term
Difference between Antigen and Antibody?
Definition
Antigen - the marker
Antibody - Protein made to match an antigen.
Term
What are the Helper T Cells?
Definition
They are the information collectors/translator cells.
Term
Job of the B Cells/ Plasma Cells?
Definition
Antibody producing/distribution cells
Term
A certain B cell and all the cells that derive from it will only make one type of antibody its whole life. What is this called?
Definition
Clonal selection
Term
Who passes on the antigen structure information to memory b cells in the bone marrow?
Definition
B Cells/Plasma Cells
Term
Who collects antigen information from the macrophages?
Definition
Helper T Cells
Term
Who confirms the antigen shape by mingling with the invader?
Definition
Helper T Cells
Term
Who brings the antigen information to the B cells in the bone marrow?
Definition
Helper T Cells
Term
Who later informs Killer T cells to attack once the antibodies have been attached to invader's antigens?
Definition
Helper T Cells
Term
Who receives antigen information from Helper T and make matching antibodies?
Definition
B Cells/ Plasma cells
Term
Who leaves the bone marrow with antibody and attach them to invader antigen?
Definition
B Cells/ Plasma cells
Term
_______ is a super antibody producer.
Definition
A plasma cell
Term
How does an antibody help rid of the body of an intruder?
Definition
1) Increases Volume :
-can't easily diffuse through tissues
-decreases the spread of infection
-easier for killer T to spot and attack
May
- It may also causes invaders to clump together, making phagocytic attack easier.
Term
What is the job of the memory B Cells?
Definition
They store antigen info of invader and produce antibodies during 2nd exposure.
Term
Who is derived from b cells and carry the specific antibody?
Definition
Memory B Cells
Term
Who continues to live in low numbers after the invader is eliminated?
Definition
Memory B Cells
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