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biology 197 section 3
lecture 2 section 3
136
Biology
Undergraduate 2
03/21/2012

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Term
Open circulatory system
Definition
Heart pumps hemolymph through vessels into
spaces surrounding the organs
Materials are exchanged between the
hemolymph and the cells in those spaces
Term
Closed circulatory system
Definition
Blood is confined to vessels that course through the organs where materials are exchanged.
Closed circulatory systems are more effective at transporting circulatory fluids over long distances in larger animals
Term
cardiovascular system
Definition
Part of the Closed circulatory system
Heart chambers
Atria – chambers that receive blood
Ventricles – chambers that pump blood
Term
Arteries
Definition
vessels that carry blood away from the heart
*arteries – arterioles*
Term
Veins
Definition
vessels that return blood to the heart
*capillaries – venules – veins*
Term
What is blood
Definition
a connective tissue with cells that are suspended in plasma
Term
What are the 4 components of blood
Definition
Plasma
Erythrocytes (red blood cells)
Leukocytes (white blood cells)
Platelets
Term
What is plasma
Definition
The liquid component of blood in which blood
cells are suspended
Term
what does plasma contain?
Definition
Mostly water, but also ions and blood proteins
*Also transports metabolic wastes, hormones, respiratory gases, etc*
Term
Erythrocytes
Definition
Lack Nuclei
biconcave shaped
contain Hemoglobin
Term
what is Hemoglobin
Definition
The iron-containing oxygen transport protein in red blood cells
Term
An assembly of four globular protein subunits. Each subunit is composed of a protein chain tightly associated with a non-protein heme group.
Definition
Hemoglobin
Term
What is the primary role of Leukocytes?
Definition
White blood cells’ primary role is to fight
infections
Term
what are the 5 different types of Leukocytes
Definition
monocytes, neutrophils,
basophils, eosinophils, and lymphocytes
Term
what do lymphocytes develop into
Definition
B and T cells
Term
what are platelets
Definition
Clotting factors that allow one to “self-seal” in the case of a small cut or scrape
Term
No nuclei – fragments of cells
Definition
Platelets
Term
hemophilia
Definition
Genetic defects that affect the clotting process
Term
Pluripotent
Definition
have the ability to develop into many different types of cells
Term
Stem cells
Definition
Replace old or damaged blood cells
Term
Erythropoietin (EPO
Definition
hormone that stimulates production of erythrocytes
Term
Fish with a 2 chambered heart
Definition
- One atrium
- One ventricle
Blood flow:
Ventricle → Gills → Aorta
Term
what makes lungfish unique
Definition
they have a 3 chambered heart
One aorta receives oxygen poor blood from the body
One aorta receives oxygen rich blood
from the lung
Term
Amphibians have a 3 chambered heart.How does it work?
Definition
Pulmonary and systemic circulation is partially separated
Amphibians supplement oxygen by absorbing it through the skin
Term
what reptiles have a 3 chambered heart and how does it work?
Definition
- turtles
- snakes
- lizards
Ventricle is partially divided by a septum
It has Two aortas
Term
what reptile has a 4 chambered heart and how does it work
Definition
crocodilians.
heart has:
Two ventricles, each with an aorta,the Two aortas are connected by a blood vessel
Term
how does the 4 chambered heart in mammals and birds work?
Definition
Two atria
Two ventricles
*Double circulation*
right side pumps oxygen poor blood
left side pumps oxygen rich blood
Term
how is unidirectional blood flow ensured?
Definition
by valves
Term
Atrioventricular valves
Definition
prevent backflow into the atria once ventricles contract
Tricuspid and bicuspid (mitral)
Term
Semilunar valves
Definition
prevent backflow into the ventricles from arteries once ventricles relax
- Pulmonary and aortic valve
Term
Heart murmur
Definition
when valves don’t close properly
Term
step 1 in mammalian circulation
Definition
Cranial vena cava and caudal vena cava deliver oxygen poor blood to the right atrium
Term
step 2 in mammalian circulation
Definition
Blood flows from the right atrium through the tricuspid valve and into the right ventricle
Term
step 3 in mammalian circulation
Definition
The right ventricle contracts,pushing blood through the pulmonary semilunar valve into the pulmonary trunk
Term
step 4 in mammalian circulation
Definition
Pulmonary trunk divides into
pulmonary arteries
Term
step 5 in mammalian circulation
Definition
Pulmonary arteries deliver blood to the lungs
Term
step 6 in mammalian circulation
Definition
Blood loses CO2 and picks up O2 in capillary beds in the lungs, then returns to the left atrium via pulmonary veins
Term
step 7 in mammalian circulation
Definition
Blood flows from the left atrium through the bicuspid (mitral) valve into the left ventricle
Term
step 8 in mammalian circulation
Definition
Left ventricle contracts and
pushes the blood through the aortic semilunar valve into the aorta
Term
step 9 in mammalian circulation
Definition
Arteries branch off the aorta and deliver oxygenated blood to the capillary beds in the head and forelimbs
Term
step 10 in mammalian circulation
Definition
More arteries branch off the aorta and deliver blood to the capillary beds in abdominal organs and hindlimbs
Term
step 11 in mammalian circulation
Definition
Capillaries, venules and veins in the head and forelimbs converge into the cranial vena cava
Term
step 12 in mammalian circulation
Definition
Capillaries, venules and veins in the abdomen and hindlimbs converge into the caudal vena cava
Term
what does the atria do in the mammalian heart
Definition
contract and push blood into ventricles
Term
what does the ventricle do in mammalian heart?
Definition
contract much more strongly and pump blood to all body organs
Term
Systole
Definition
contraction phase of the heart
Term
Diastole
Definition
relaxation phase of the heart
Term
Heart rate
Definition
number of beats per minute
Term
Stroke volume
Definition
the amount of blood pumped by the left ventricle in each contraction
Term
in the mammalian heart what keeps blood flowing in the proper direction
Definition
Four valves.
Two atrioventricular valves – Tricuspid and bicuspid (mitral)
Two semilunar valves – pulmonary and aortic
Term
Pulse
Definition
the rhythmic stretching of the arteries caused by the pressure of blood driven by the contraction of the ventricles
Term
lub-dup
Definition
lub – caused by blood recoiling after hitting the closed atrioventricular valves
dup – sound caused by blood recoiling after hitting closed semilunar valves.
Term
when does a heart murmur occur
Definition
when one or more valves do not function properly.
i.e.:Blood squirts backward through the valves.
Term
what does the Sinoatrial (SA) node or pacemaker control?
Definition
the rate and timing of contraction of cardiac muscles (sinus rhythm)
Term
what does the Atrioventricular (AV) node do?
Definition
delays electrical impulses to insure the atria empties before the ventricle contracts.
Term
how is blood circulation governed
Definition
by physics
Term
Arteries
Definition
thick walled to withstand the high pressure associated with contraction
Term
Veins
Definition
thin walled, and convey low pressure blood back to the heart as a result of muscle contractions
Term
what causes blood to flow slow?
Definition
the aorta divides into arteries and arteries divide into arterioles.
slow blood flow maximizes the amount of time for transport of substances across capillary walls
Term
is blood pressure higher in arteries and veins
Definition
arteries
Term
Systolic pressure
Definition
High blood pressure when the ventricles of the heart contract
Term
Diastolic pressure
Definition
Lower blood pressure when the ventricles of the heart are relaxed
Term
what is Capillary Function
Definition
The only blood vessels with thin enough walls to allow transfer of substances from the blood to the interstitial fluid
- Diffusion – oxygen and carbon dioxide
- Blood pressure
- Osmotic pressure
Term
capillaries are not always filled with blood all the time....
Definition
Eating – increased blood flow to digestive tract
Exercising – increased blood flow to skeletal muscle
*Controlled by pre-capillary sphincters*
Term
Only about 85% of all fluid that enters the interstitial fluid makes it back into the veins on its own. what happens to the remaining 15%?
Definition
returned to the blood stream via the lymphatic system, a series of vessels that attaches to the vena cava near its junction with the right atrium.
Term
Lymph
Definition
clear water (Latin)
Term
Lymph vessels
Definition
have small valves that prevent fluid (lymph) from flowing backwards
Term
Lymph nodes
Definition
are centers that filter the lymph, and attack viruses or bacteria that are
circulating
Term
lymphocytes
Definition
type of leucocyte
Term
what genetic factors is cardiovascular disease Influenced by?
Definition
Influenced by lifestyle choices
- smoking, alcohol
- lack of exercise
- diet rich in animal fat
- high cholesterol
Term
cholesterol
Definition
LDL's: Low density Lipoproteins. Bad cholesterol deposits plaques
HDL's: High density Lipoproteins. Good cholesterol reduces plaques
Term
Atherosclerosis
Definition
hardening of the artery walls
Term
Hypertension
Definition
High blood pressure
Term
Hypertension promotes atherosclerosis. what happens if this is left untreated?
Definition
heart attack: interrupt blood supply to the heart
stroke: Interrupt blood supply to the brain
Term
Every organism must
Definition
exchange materials and energy with its environment.That exchange ultimately occurs at the cellular level.Unicellular organisms have a direct exchange.Simple diffusion
Term
Multicellular organisms have evolved physiological systems for exchange and transport of materials. why?
Definition
These systems ensure that no substance has to diffuse very far
Term
what is gas exchange?
Definition
The uptake of molecular oxygen from the
environment and the release of carbon dioxide to the environment
Term
what is gas exchange often referred to as?
Definition
respiration, but should not be confused with the metabolic process of cellular respiration
Term
Respiratory medium
Definition
the source of oxygen
Term
Respiratory surface
Definition
the part of the body where gas exchange occurs. examples:
- gills (fish, salamanders, clams)
- skin (earthworms, some amphibians)
- tracheae (most insects)
- lungs (reptiles, birds, mammals)
Term
Air is a better respiratory medium than water. why?
Definition
because oxygen diffuses more readily through air.
Term
how do High temperatures cause respiratory problems for aquatic animals?
Definition
because oxygen is not as abundant in water, and diffuses away faster at high temperatures.
Term
Oxygen availability
Definition
decreases with altitude
Term
what do most insects use for gas exchange?
Definition
trachaea such as:
- spiracles
- air sacs
Term
Fish gills use countercurrent flow to
Definition
maximize gas exchange.
Gills are supported by gill arches that lie between the mouth and the opercular flaps. Water flows unidirectionally into the mouth, over the gills, and out from under the opercula
- double pump system
Term
Bird lungs use unidirectional air flow to maximize gas exchange. what is the process
Definition
Trachea → bronchi → parabronchi → air capillaries
*Parabronchi coalesce into larger bronchi, and return air back to the trachea*
Term
Mammalian respiration
Definition
Glottis (epiglottis)
Larynx
Trachea
Bronchi
Bronchioles
Alveoli
Lungs - occur in one location in the body
Term
Since lungs are not in direct contact with the rest of the body....
Definition
the circulatory system must bridge the gap
Term
Negative pressure breathing
Definition
Works like a suction pump that pulls air
instead of pushing it into the lungs.
Term
how does negative pressure breathing work?
Definition
Contraction of the diaphragm and rib muscles enlarges the rib cage, enlarging the lungs,which then drops the pressure, and air rushes in
Term
Tidal volume
Definition
the volume inhaled and exhaled with each breath
Term
Vital capacity
Definition
the maximum tidal volume during forced breathing
Term
Residual volume
Definition
the amount of air that never leaves the lungs
Term
Hemoglobin
Definition
protein that consists of four subunits, each of which contain a cofactor
called a heme group with an iron atom at its center. this is function sensitive to environmental factors such as shifts in PH
Term
what is Function is sensitive to
environmental factors,(e.g. shifts in pH)?
Definition
Oxygen Transport
Term
where are breathing control centers located?
Definition
in two areas of the brain stem
- medulla oblongata (autonomic functions)
- pons
*Key-in on CO2 concentrations
in the blood (and subsequent changes in pH)*
Term
Step 1 of Carbon Dioxide transport
Definition
CO2 produced by body tissues diffuses into the interstitial fluid.
Term
step 2 of Carbon Dioxide transport
Definition
90% of the CO2 produced by the body tissues attache to red blood cells
Term
step 3 of carbon dioxide transport
Definition
Some CO2 is transported by hemoglobin
Term
step 4 of carbon dioxide transport
Definition
Most CO2 reacts with water to form
carbonic acid (H2CO3)
Term
step 5 of carbon dioxide transport
Definition
H2CO3 (carbonic acid) dissociates into HCO3 - and H+ ions
Term
step 6 of carbon dioxide transport
Definition
Hemoglobin binds to most of the H+, preventing it from acidifying the blood
Term
step 7 of carbon dioxide transport
Definition
Most of the HCO3- diffuses into the plasma where it is carried to the lungs
Term
step 8 of carbon dioxide transport
Definition
In the lungs, HCO3- diffuses into red blood cells, and converts back to H2CO3
Term
step 9 of carbon dioxide transport
Definition
H2CO3 is converted back into carbon dioxide and water
Term
step 10 of carbon dioxide transport
Definition
Carbon dioxide is unloaded from hemoglobin and released into the interstitial fluid
Term
step 11 of carbon dioxide transport
Definition
Carbon dioxide diffuses into the alveolar space, and is then expelled during
exhalation
Term
Excretory systems of many animals use three different processes. what are these processes?
Definition
filtration, secretion, and reabsorption
Term
why is extracellular fluid filtered
Definition
so it does not contain cells or macromolecules.
Filtrate flows through tubules associated with the excretory system, and is secreted or reabsorbed as necessary. For example: Urine
Term
what is salt & water balance influenced by? how do animals react to this?
Definition
The environment.
1)Terrestrial animals must conserve salts and water because both can be rare
2)Marine animals have an abundance of salt, but must combat water loss to their environment as a result of osmosis
3)Freshwater animals have an abundance of water,but not salts
Term
what are Carbohydrates and fats metabolized to?
Definition
water and carbon dioxide that are relatively easy to eliminate
Term
what does Catabolism of proteins and nucleic acids produce?
Definition
nitrogenous wastes (as well as water and carbon dioxide) that must be eliminated
Term
Ammonia
Definition
the most common way nitrogen is excreted because it is highly soluble in water and diffuses easily, but is toxic
Term
Urea
Definition
non-toxic way nitrogenous waste is excreted
- excretion can result in a lot of water loss
Term
Uric acid
Definition
also non-toxic form of excreting nitrogen: forms a colloidal suspension in urine, but its excretion loses very little water
Term
Protonephridia
Definition
excretory organ of a flatworm consists of a tubule and a flame cell
Term
Metanephridia
Definition
paired excretory organs of Annelids
Term
Malpighian tubules
Definition
a series of tubules used by insects as a highly effective way of excreting nitrogenous wastes with very little water loss
Term
Kidney
Definition
the main excretory organ of vertebrates
Term
Nephron
Definition
the functional unit of the kidney
-using Tubules and blood vessels
Term
Filtration of the nephron
Definition
each one has a ball of capillaries
called a glomerulus that filters blood
Term
Tubular reabsorption
Definition
filtrate from the glomerulus flows into the renal tubule and is modified as ions, nutrients and water are reabsorbed into the blood stream
Term
Tubular secretion
Definition
filtrate in renal tubule is further modified until it can be excreted
Term
Process of filtration
Definition
Blood enters the glomerular capillaries via afferent arterioles and leaves via efferent arterioles

Blood then flows to the peritubular capillaries which secrete waste materials into the urine, and carry away absorbed substances
Term
where is Bowman's capsule located?
Definition
the beginning of the renal tubule and encloses the glomerular capillaries
Term
Podocytes
Definition
cells of Bowman’s capsule that are in direct contact with the glomerular capillaries
Term
Renal tubule
Definition
converts glomerular filtrate into urine
Term
Urine that is excreted is much more concentrated than what?
Definition
the extracellular fluid that was initially
filtered
Term
what is the function of the kidney? How does the function work?
Definition
filters blood, processes filtrate into urine, releases urine
Kidney→Ureter→Urinary Bladder→Urethra
Term
Proximal convoluted tubule
Definition
In the kidney:filters most of the glomerular filtrate
Term
Loops of Henle
Definition
In the kidney:makes the urine more concentrated by means of countercurrent multipliers
Term
Distal convoluted tubule
Definition
In the kidney:the top end of the ascending limb of the loop of Henle
Term
Collecting duct
Definition
In the kidney:distal convoluted tubules of many nephrons join and empty into the renal pelvis
Term
why is the kidney important in mammals?
Definition
Kidneys produce urine, maintain acid-base balance, and osmoregulate the body fluids of an organism
Term
what causes kidney failure
Definition
retention of salts and water, and a decrease in pH, and can result in death
Term
How is kidney failure treated?
Definition
dialysis, or in extreme cases, by kidney transplant
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