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Biology 114 Section 3
Dr. Lane's Lecture
264
Biology
Undergraduate 1
11/22/2012

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Term
What are the three main requirements for respiration?
Definition
DIFFUSION of gases
MOIST membranes
Gases must be in SOLUTION
Term
Gases diffuse through moist membranes _____ their concentration gradients
Definition
Down
Term
True or False: Diffusion relies upon a gradience
Definition
True; the gradient allows for particles to move from on place to another.
Term
What is the relationship between the rate of diffusion and the density of the medium.
Definition
The rate is inversely related to the density of the medium
Term
What is the definition of diffusion?
Definition
Molecules move from an area of ____ concentration to one of ___ concentration
Term
True or False: Diffusion works well over long distances.
Definition
False; diffusion works well over short distances.
Term
What can Fick's Law do?
Definition
Calculate the diffusion of a gas.
Term
What is the equation for Fick's Law?
Definition
Diffusion coefficent x gradient x area/thickness
Term
How are aquatic creatures structured to maxmize diffusion?
Definition
Since most are thin and long, they have a minimized thickness and maxmized area of exchange.
Term
What two problems do animals face with diffusion?
Definition
They need to increase their surface area since they grow and their volume grows. They also need better ways to get rid of CO2 and take in O2 since metabolic processes increase with movement.
Term
Name four ways Large animals with high metabolic rates adapt to maximize respiratory gas diffusion rates. Off the two, which are bulk flow systems?
Definition
-increasing surface areas for gas exchange
- maximizing partial pressure gradients across surfaces
by decreasing their thickness
- ventilating the outer surface with respiratory medium
- perfusing the inner surface with blood
Term
True or False: 2 dimensional organisms require little or no equipment for respiration because diffusion is adequate
Definition
True
Term
True or false:3 dimensional organisms or larger organisms do not need to supplement diffusion
Definition
False; they are large, so its hard for gases to simply diffuse from head to toes.
Term
What are bulk flow systems?
Definition
brings the highest concentraiton and the lowest into contact to maximize diffusion and ensure gradient.
Term
What effect does dessication have on diffusion
Definition
Dessicaation prevents diffusion since diffusion needs a moist membrane.
Term
How does a plant fend off against dessication?
Definition
waxy cuticle on plants (except at stomates and lenticels)
Term
How do animals fend off against dessication?
Definition
invagination of membranes (lungs inside chest, tracheal systems of insects)
Term
Name two parts of a plant that are responsible for gas exchange?
Definition
Stomates and leaves.
Term
What are chanocytes? Where are they found?
Definition
Found on sponge.Choanocytes create water current movements with their flagella
Term
What are antistanation devices?
Definition
They are simply bulk flow systems.Help regulated the water/air in the gills/lungs.
Term
What two factors limit gas exchange in aquatic animals?
Definition
low diffusion rate
low O2 level in water
Term
What two problems do aquatic animals face due to their environment?
Definition
1. Oxygen concentration in water diminishes as water temperature rises

2. Their metabolism and the work required to move water over gas exchange surfaces increase, too
Term
True or false; water has very little oxygen compared to air.
Definition
True; its even less in warm salt water.
Term
As temperature ______, O2 concentration in water decreaes.
Definition
Increases.
Term
True or false: The demand for oxygen does not increase if an organism is moving around.
Definition
False; demand increases since it is moving around and being active.
Term
Explain how the physical adaption of gills work. Which organism has then?
Definition
Aquatic arthpods. They are actually gas-filled extensions of the tracheal system. The thin gill membranes allow gas exchange with water.
Term
Explain behavioral adaptions where O2 may not be present in aquatic environments?
Definition
Many insects and invertebrates carry gas bubbles with them during dives.
Term
What are two ways to work around the problem of less available O2?
Definition
Having an efficient transport system and having respiratory pigments to increase oxygen transport.
Term
True or false: Water is too viscous (compared to air) to draw inside the body for gas exchange
Definition
True
Term
How do gills work?
Definition
Gills bring a large fraction of the blood or hemolymph near enough to water to allow for gas exchange through a countercurrent exchange system.
Term
How do land organisms prevent dessication?
Definition
To minimize water loss, the respiratory surface has been inverted and internalized.
Term
How do amphibians respirate?
Definition
Use their alveolar lungs through positive pressure.
Term
What is positive pressure?
Definition
Raising the air pressure above that of the lung is positive pressure breathing.To do this, the animal closes his mouth and forces the air down the mouth due to pressure.
Term
How do mammmals and reptiles respirate?
Definition
They use alveolar lungs through negative pressure.
Term
How do birds respirate?
Definition
They use parabronchial lungs and use negative pressure and compression.
Term
Explain the trachael system of the grasshopper?
Definition
Invaginations of body wall lead directly to each cell. The tracheas branch out to each cell.
Respiratory surface area is closely matched to body size.
Term
How does a negative pressure system work?
Definition
- suck air into their lungs to breathe in
- squeeze air out of the lungs to breathe out
Term
How does the diaphragm aid in breathing?
Definition
When it contracts, it pills the lungs down, allowing for negative pressure to pull air in.
Term
What type of muscle is the diaphragm? What is the definition of this muscle?
Definition
Diagrpharm is a straited muscle--it doesn’t contract unless a nervous system makes it contract.
Term
What are the external intercostal muscles?
Definition
They help raise the chest
Term
What does the internal intercostal muscle?
Definition
Lowers the chest.
Term
True or False; external intercostal muscles don't work when you relax the chest.
Definition
False; the internal intercostal muscles don't work.
Term
Explain the process of inhalation. Is it active or passive?
Definition
At rest, Inhalation is active. It results from contraction of the diaphragm and external intercostal muscles, which creates a negative pressure in the thoracic cavity, sucking air into the lungs
Term
Explain the process of exhalation. Is it active or passive?
Definition
At rest, Exhalation is passive. It results from the relaxation of the diaphragm and external intercostal muscles, and the settling of the chest onto the abdominal organs. This forces air out of the lungs
Term
During inhalation, the diaphragm ____
Definition
Contracts (moves down)
Term
During exhalation, the diaphragm ____
Definition
relaxes (moves up)
Term
True or false; the negative pressure created inside the lungs only occurs if the lungs stick to the chest.
Definition
True
Term
What increases the surface area of the lungs in humans?
Definition
Alevoli sacs.
Term
What holds the lungs together?
Definition
Pleura
Term
What happens to the alveolar pressure during inhalation?
Definition
Becomes negative.
Term
What happens to the alveolar pressure during exhalation?
Definition
Becomes positive.
Term
What happens to the pleural cavity pressure (space between chest and lungs) during inhalation?
Definition
Becomes more negative.
Term
What happens to the pleural cavity pressure (space between chest and lungs) during exhalation?
Definition
Becomes less negative.
Term
Explain how the pleura are held together?
Definition
Leaflates are stuck together by surface tension by water molecule and negative pressure.
Term
What two things do pleura have due to moisture?
Definition
Negative pressure and surface tension
Term
What is surfactant?
Definition
Surfactant permits the leaflets to slide against each other, lowering surface tenssion
Term
Why do we need surfactant?
Definition
The leaflets aren't dry, so they can't easily slide against each other. The membranes are moist, which means the leaflets stick.
Term
The rib cage has a tendency to move___ and the lung has tendency to collapase_____.
Definition
Outwards, inwards
Term
What two things does surfactant do besides lower surface tension?
Definition
Lowers the work of the lung and keeps aveloi open.
Term
What three things can surface tension and negative pressure hold together?
Definition
Lung, chest, and pleural leaflets
Term
The_______ of the chest wall pulls the lungs outward during inhalation
Definition
Recoil (elasticity)
Term
The_______ pulls the stretched lung-chest inward at the end of inhalation
Definition
Lung elasticity
Term
True or False; we have no way of calculating the amount of air, we can onlu count the differeence
Definition
1
Term
Birds contain ____ and Bird's air flows in ____ ____
Definition
Air sacs and One way
Term
How does a bird accompish gas exchange?
Definition
The parabronchus lung has channels that come into contact with capparriliaries, increasing surface area of exchange.
Term
Alveloar-cappillary membrane is thin/thick
Definition
Thin
Term
Pulmonary venules are what color? Why?
Definition
They are red since they contain oxyignated blood.
Term
Pulmonary arteries are what color? Why?
Definition
They are blue since they contain deoxyingated blood.
Term
Difference between artery and vein? What color are each?
Definition
Arteries (red) go away from the heart while veins (blue) go towards heart.
Term
What are Type 1 cells in the avelous?
Definition
They form the lining of the avelous and air must pass through them to get to the cappaliaries.
Term
What are Type 2 cells in the avelous?
Definition
They produce surfactant.
Term
What are aveolar macrohpages?
Definition
They help eat bacteria and clean up avelous?
Term
True or false; the bronchi are not lined with cilli
Definition
False; cilli is present to push mucus out of our lungs and into or mouth to spit.
Term
Passage ways between the avelous are known as what?
Definition
Pores of Kohn
Term
Explain the avleolar-cappilary model. How is a partial pressure gradient made? What are the two bulk flow systems?
Definition
We have two bulk flow systems that bring the liquid and gases together at the exhchange membrane, which are the cardiovascular apparatus and ventilatory apparatus. The cardiovascular system pumps blood into the alveolar-capillary membrane. High oxygen levels in the air can diffuse into the low levels in the blood, so there is a partial pressure gradient.
Term
What are the partial pressures of CO2 and O2? Which one has a higher gradient?
Definition
160 mmHg O2 and 0.3 mmHg CO2. O2 has a higher gradient.
Term
Explain how O2 moves down its partial pressure gradient?
Definition
O2 in air or water steps down its gradient across the alveolar capillary membrane to the blood, from capillaries to interstitial fluid, and from interstitial fluid across cell membranes
Term
Explain how CO2 moves down its partial pressure gradient?
Definition
CO2 steps down its gradient across cell membranes into the interstitial fluid, from there, across the capillary membrane into the blood, and from the blood across the alveolar-capillary membrane into alveolar air
Term
Why is CO2's gradient less sharper than O2's?
Definition
CO2 is 20 times more soluble than O2 which means Co2 does need as much of a push to get out of the solution.
Term
Solubility decreases with ________ temperature and with _______ salt content
Definition
Increased;increased
Term
What acid does CO2 form when put into a solution? What are byproducts of this acid when it dissociates?
Definition
Carobonic acid H2CO3 and the byproducts are H+ and HCO3-
Term
What is partial pressure of O2 in artierlized and venus blood?
Definition
PO2 Arterialized blood =97 mmHg and PCO2 Venus blood = 40 mmHg
Term
What is the dissovled and bound concentration in arterilized blood? What are the %'s?
Definition
Dissolved = 0.29 ml/100 ml of blood and bound = 19.21ml/100ml blood. Dissolved 1.5% and bound 98.5%
Term
What are two things repiratory pigments can do?
Definition
Increase solublity of O2 (increasing its transporation ability) and act as buffer for Co2.
Term
What are the three major respiratory pigments?
Definition
Hemoglobin, myglobin, and hemocyacin
Term
What is hemoglobin?
Definition
A 4-protein complex that contains ferrous iron bound to heme. It is red to maroon, depending on oxygen saturation
Term
What is myoglobin?
Definition
Related to hemoglobin, but is used specifically to store oxygen in muscle
Term
What is hemocyacin?
Definition
A protein complex with copper. It is blue when oxygenated, and colorless when un-oxygenated
Term
What is an alosteric molecule? What molecule have we talked about is an alosteric molecule?
Definition
A molecule that changes shape when something binds to it. A molecule we know of is hemoglobin.
Term
How are sickle cells caused?
Definition
Genetic mutation of the hemoglobin
Term
Why do sickle cells become so sticky?
Definition
Deoxygenated hemoglobin-S polymerizes into hemoglobin strands that deform the cell. The cells become sticky
Term
What are two problems that sickle cells can cause?
Definition
blocking blood flow and early breaking apart (rupture of sickled cells) leads to anemia
Term
True or false; Hemoglobin in oxidized by oxygen.
Definition
False; it is oxygenatated, not oxidized.
Term
How do respiratory pigments work?
Definition
They use Fick's Law and work by increasing the effective concentration gradient. They generally have a high affinity to oxygen.
Term
What is cooperativity in hemoglobin?
Definition
Once one oxygen binds to hemoglobin, the other three can easily bind onto it.
Term
O2 binds readily in lungs at ____ PO2, but dissociates in tissues at ___ PO2 .
Definition
high; low
Term
What is the Bohr Effect?
Definition
Acidity causes hemoglobin to unload oxygen.
Term
What is association?
Definition
When oxygen binds to hemoglobin?
Term
What is dissociation?
Definition
When oxygen comes off hemoglobin.
Term
How much oxygen is lost when hemoglobin moves from the lungs to tissues?
Definition
25%, so 75% is still remaining.
Term
What increases to add oxygen to hemoglobin? What decreases to unload oxygen from hemoglobin?
Definition
Partial pressure.
Term
Partial pressure is ____ in the lungs and ____ in the tissues.
Definition
High;low
Term
What is the p50?
Definition
Expresses O2 binding affinity.
Term
What does a lower p50 Mean? (left shift)
Definition
Higher affinity and better loading of oxygen due to lowered partial pressure.
Term
What does a higher p50 mean? (right shift)
Definition
Lower affinity and decreased loading of oxygen due to increased partial pressure.
Term
What are three ways the Oxygen Dissociation Curve affinity can change?
Definition
Chain substitution
Amino Acid Substitution
Microenvironment around hemoglobin
Term
What is Chain Substitution?
Definition
Beta chains are substitued
Term
What is Amino Acid Substitution?
Definition
Changes in amino acid sequence to change shape of molecule.
Term
What is the microenvironment around the hemoglobin?
Definition
Acidity, which may make a hemoglobin unload oxygen.
Term
What two factors can change an affinity curve?
Definition
Temperature or pH
Term
Why does a right shift favor unloading of O2?
Definition
Bohr's effect; the acidity decreases the the hemoglobin unwinds and releases oxygen.
Term
What are the two forms of hemoglobin? Which is oxygen rich and which is oxygen poor? Which one is accidic?
Definition
Oxyhemoglobin Oxygen rich KHbO2
Deoxyhemoglobin Oxygen poor HHbCO2 (acidic)
Term
How is CO2 distributed in the blood?
Definition
7% is simply dissolved gas
23% is bound to amine groups on Hb, forming carbamino complexes (= carbaminohemoglobin)
70% of CO2 is carried in a buffered form, as sodium bicarbonate (NaHCO3), so it is bound
Term
What are the two forms of the bound CO2?
Definition
(1) the amino group in the hemoglobin, and (2) bicarbonate.
Term
What does the amine group in hemoglobin pick up?
Definition
Co2
Term
What does the carboxyl group in hemoglobin pick up?
Definition
Hydrogen ions
Term
What does the iron in the blood pick up?
Definition
Oxygen
Term
Why does hemoglobin act as a buffer?
Definition
It can pick up hydrogen (H+) ions.
Term
Describe the entire process in how CO2 leaves the tissues, comes into the red blood cell, and moves out into the lungs.
Definition
When the red blood cell comes to the tissue, Co2 is produced at the tissue level, diffuses across cell membrane into intersitital fluid and acrooss the capaliray wall into the plasma and then enters the red cell. The red cell has carobnic anyhydrase. CO2 hydrates to form carobnic acid which dissociates into H+ ions and bicarbonate. The H ions combine with the carboxly of the hemoglobin, and CO2 combines with amino group. Bicaronate is exported out into the plasma. To maintain electrical charge, Cl moves into the red cell. When the red blood cell comes to the lung, bicarbonate comes in and CL leaves. H+ and bicaronate combine to form carobnic acid. Enzyme changes the cabonic acid to CO2 and it moves into the lungs out of the body.
Term
Where is the rhythm center for breathing located?
Definition
Medulla
Term
Where are the modulating center for breathing located?
Definition
Pons
Term
Which nerve is used in active ventilation and not in quiet breathing?
Definition
Internal intercostal muscles.
Term
Which experiences more AP bursts, active ventiliation or quiet breathing?
Definition
Active ventiliation.
Term
The phrenic nerve goes to the ____ during breathing.
Definition
Diaphragm
Term
True or false; at rest, exhalation is passive.
Definition
True
Term
The external intercostal nerves go to the_____ during breathing.
Definition
ribcage inspiratory muscles
Term
The internal intercostal nerves go to the ______ during breathing.
Definition
ribcage expiratory muscles
Term
What are chemoreceptors?
Definition
They detect the bloods CO2 and Hydrogen content.
Term
What are the central chemoreceptors? What are the the peripheral chemoreceptors?
Definition
Pons and medulla; aoritc and carotid body.
Term
Where are chemoreceptors and baroreceptors found?
Definition
The aortic arch.
Term
What are baroreceptors?
Definition
Detect distortions of the blood vessels and their walls (measure BP).
Term
What are carotid bodies?
Definition
Detect chemical nature of the blood.
Term
Explain how the central chemoreceptors work in the medulla?
Definition
The vascular of the brain has a blood brain barrier. Barrier does not let H cross, but lets CO2. THE CO2 moves into the cerobrospinal fluid. In this fluid, the enzyme carbonic anhydrase hydrates CO2 into carbonic acid, which dissociates into bicarbonate and hydrogen, ad H+ stimulates the chemorreceptors.
Term
What are the main detecting differences between the cental and peripheral chemoreceptors?
Definition
Central detects H made from CO2, and peripheral detects H from non-CO2 sources like metabolism.
Term
At what partial pressure is ventiliation stimulated?
Definition
When it falls at or below 60 mmHg, which makes receptors responsive.
Term
What two molecules stimulate ventilation?
Definition
H+ and CO2
Term
Why is bulk flow used in large and thick organisms?
Definition
Helps bypass thickness to allow diffusion to work more efficiently.
Term
An increase in size must be accompanied by a ____ ____ fluid distribution system
Definition
bulk flow
Term
Fluid movement requires ___ ____
Definition
Gradient makers
Term
In order for their to be a sharp gradient for exchange, there needs to be ?
Definition
Two bulk flow systems. They work against each other from high to low.
Term
In order for their to be a shallow gradient for exchange, there needs to be ?
Definition
1 bulk flow system.
Term
What are channocytes?
Definition
In sponges, these collar cells create water current movements with their flagella.
Term
How do sponges empty their cavities?
Definition
Channocytes move water into openings known as ostia. The muscles in the sponge contract and the cavity is emptied?
Term
How do Cnidaria empty their cavities?
Definition
It’s food is brought into the opening by the tentacles. It moves them into the mouth and then into the exit. After entering the body, the animal contracts and expels the food. There is only ONE opening…the mouth in which food came in.
Term
How do flatworms empty their cavities?
Definition
It’s food is brought into the pharnyx. It moves them into the mouth and then into the exit. After entering the body, the animal contracts and expels the food. There is only ONE opening…the mouth in which food came in.
Term
How do jellyfish move water into their canals?
Definition
Jellyfish have radial channels. External water travels through these channels in a circular movement. To move the liquid, the jelly contracts and contorts its body to raise its pressure locally. They can then move the water in their channels.
Term
Difference between the whole body movements of the nematode and the flatworm?
Definition
Flatworms move interstitial fluids around cells. Nematodes move coeloemic fluid in the body cavity.
Term
True or false; Nematodes have a pseudocavity
Definition
True; they do not have a mesoderm lining, which is needed for a true body cavity.
Term
What is systolic pressure?
Definition
The blood pressure from the heart
Term
What is diastolic pressure?
Definition
The blood pressure the heart works against.
Term
What are some characteristics of the open circulation?
Definition
- Few blood vessels
- No capillaries connecting arteries and veins
- ‘Blood’ enters - blood sinuses, bathes organs directly
- **** Blood and Interstitial Fluid are the same: hemolymph
-
Term
What are some characteristics of the closed circulation?
Definition
- Discrete Arteries and Veins connected by capillaries
****- Blood is separate from Interstitial Fluid
- With a good pump, can create high pressure
***- Exchanges between the blood and tissues occur across the thin walls of capillaries
Term
What two systems are involved in the double circulation?
Definition
Systemic and pulmonary
Term
True or false; High speed pumps (macropumps) connected to large vessels are preferable to
Low speed pumps (micropumps) connected to small vessels
Definition
True
Term
True or false; A muscle pump (heart) is less energetically efficient than a flagellum and/or cilium attached to small tubes
Definition
False; its more energetically efficent.
Term
In what two ways is cost of moving fluids measured?
Definition
-Resistances to the flow of blood in blood vessels (diameter of the tube)
-Effort the heart puts into overcoming the pressure in blood vessels
Term
______ is required to overcome the “resistances to flow”
Definition
Energy
Term
What are three resistances that slow down flow of fluids?
Definition
length of tubes
viscosity of fluids
decreasing diameter of tubes
Term
What is Posieulle's Formula? What does it measure?
Definition
Flow = Pressure gradient / radius/length/viscosity. Flow increases with pressure gradient and increasing radius
Term
Why is length a resistance to flow?
Definition
Drag is going to be higher if this tube is longer.
Term
Large vessels have ____ surface area to volume ratios, so ____ drag
Definition
small; less
Term
Small vessels have ____ surface area to volume ratios, so ____ drag
Definition
large; more
Term
True or false: influence of wall resistance lessens with increasing diameter
Definition
True
Term
What are the two main reasons blood is viscous?
Definition
Number of cellular elements in blood
Concentration of proteins in blood
Term
Is drag less/more in wide/narrow tubes?
Definition
Less in wide and more in narrow.
Term
Describe the arteriole system? What happens to Surface area, BP, and velocity?
Definition
Arteriole system is branching tubes that become increasignly short and narrow. The BP falls drammatically at the end of the arteriole system from high to low. Surface area increase with a decrease in BP. Velocity also decreases once the branching occurs.
Term
______ have the most variable diameter of vessels
Definition
Arterioles
Term
What is the Law of Continuity for Speed of flow?
Definition
Flow speeds up as fluids enter a narrower tube.
Or, slows down as it passes from a narrow tube into a wider tube
Term
How does blood follow for the law of continuity? Why?
Definition
The blood does not follow this law. It is fast in transit (wide tubes) and slow in transfer (narrow) in order for diffusion to happen.
Term
Why is the surface area of the cappalilares so large?
Definition
They branch out to many organs, giving them a larger area.
Term
How is the velocity of the blood in a certain area calculated?
Definition
Volume of the blood/the area in which it flows (cappillaries, arterioles, etc.)
Term
What is the velocity of the vena cava?
Definition
20 cm/sec
Term
What is the velocity of the aorta?
Definition
28 cm/sec
Term
What is the velocity of capillaries?
Definition
0.035 cm/sec
Term
What has the growth of chambers of the heart through evolution signified?
Definition
This progression has led to an increasing separation of blood flow to the gas exchange organs and to the rest of the body.
Term
Explain how the blood comes into the heart from the body and moves to the lungs.
Definition
The blood above the heart (deoxyginated) is moved to the right atrium by the superior vena cava. Blood from below the heart comes in through the inferior vena cava. The right atrium contracts to open right AV valve and move blood to right atrium. The right ventricle pumps contracts to close the right AV value and open hte pulmonary valve to send the blood to the lungs.
Term
Explain how blood comes from the lungs back into the heart and goes throughout the body.
Definition
The blood (oxyignated) moves through the pulmonary veins to the left arium. It contracts and it fills into the left ventricle. The ventricle contracts and the mitric valve is close and the aoritc valve is opened. The blood goes out through the body and as pressure falls the aortic valve is shut.
Term
Which vessels are slow and small (narrow), and used for transfer?
Definition
Capillaries
Term
Which vessels are fast, large (wide), and used for transit?
Definition
Aorta and all other vessels.
Term
What is isovolumtertic contraction?
Definition
a contraction that doesn’t change the volume of the blood in the heart.
Term
Describe what happens in the two phases of the cardiac cycle?
Definition
In systole, the ventricles contract and partially empty; and diastole, in which they relax and fill.
Term
Explain how the lub sound is made?
Definition
The lub sound is caused by the shutting of the bicuspid/mitral valve (left AV valve) and the tricuspid valve (right AV valve). This occurs when blood from the atrial chambers enter the ventricles.
Term
Explain how the dub sound it made?
Definition
The dub sound is caused by the shutting of the aortic valve and the pulmonary valve. This occurs when the blood from the ventricles are pumped out into the lungs and the rest of the body.
Term
What are the four parts of the left atrium's cardiac cycle? Which are systole and diastole? When is lub and dub heard?
Definition
1 = filling phase
2 = isovolumetric contraction
3 = emptying phase
4 = isovolumetric relaxation
Diastole is 4 and 1 and Systole is 3 and 2
Lub is made after 1, and dub is made after 3.
Term
What is the equation for Cardiac Output?
Definition
Cardiac Output = Heart Rate X Stroke Volume (Force of contraction)
Term
What are the two pacemakers in the heart? where are they located? which one dominates the other?
Definition
Sinal Atrial Node and (SA Node) and the AV node. Right atrium. SA dominates AV.
Term
Where does the sympathetic nerve connect to the heart, where does the parasympathetic nerve connect? What is the parasympathetic nerve called?
Definition
Sympathetic goes to the heart muscle. Parasympathetic goes to the AV and SA node. The parasympathetic is called vegas nerve.
Term
Which pacemaker sets the heart rate?
Definition
SA node
Term
How does sympathetic nervous system speeds up the heart rate?
Definition
The sympathetic nervous system speeds up the heart rate by depolarizing the pacemaker membrane sooner than normal. This causes the potential to reach threshold sooner and thus generate an action potential sooner
Term
How does parasympathetic nervous system speeds up the heart rate?
Definition
The parasympathetic nervous system slows the heart rate down by hyperpolarizing the pacemaker membrane, and slowing the depolarization. This causes the potential to reach threshold more slowly and thus delays the appearance of the action potential
Term
Heart rate is controlled by the ____ ___ ___, which affects the excitability of the ____ ____
Definition
Autonomic Nervous System; pacemaker cells
Term
Why is calcium important in the heart?
Definition
It is useful excitation-coupling in the body.
Term
What is the end diastolic volume?
Definition
The volume of blood that is trapped in the heart when the 2 vales are shut
Term
How does the refractory period of the heart prevent tetanus?
Definition
It lasts throughout the contraction.
Term
What is the end systeolic volume?
Definition
the heart does not empty entirely with each beat. There is always a residual volume left in the chamber
Term
The sympathetic nervous system _____ the force of contraction. This causes the heart to _____ more blood
Definition
increases; empty
Term
____, from the adrenal medulla, ______ the sympathetic action. It binds to ______.
Definition
Adrenaline, increases, b-receptors
Term
How do B-blockers lower the heart rate?
Definition
b-blockers bind to b receptors and reduce adrenaline & sympathetic action on the heart muscle, lowering the force of contraction, thus lowering blood pressure. They also slow the heart rate
Term
What are pre-cappillary spchinters?
Definition
Pre cappilary spcincters adjusts the flow of the blood to the supply and demand of the tissue. The sphinters relax if tissues need more blood.
Term
What do capillaries do?
Definition
form an exchange sheet for
diffusion
bulk flow
active transport
Term
What type of cell are capillaries?
Definition
Endothelial cells
Term
What are some ways to cross a capillaries?
Definition
Diffusion through pores, diffusion through the cells, and diffusion through the water-filled pores.
Term
What are three types of capillaries? Where are they located?
Definition
Continous (muscle,skin,tissue), fenestrated (kidney, pancreas, gall bladder), and discontinuous (liver, spleen, ovaries)
Term
What is the sponging effect of proteins?
Definition
The onctotic pressure of proteins as they tend to attract water to themselves. They act like sponges in that matter.
Term
What is the equation for Starling’s Principle of the Capillaries?
Definition
Effective flux (flow)=Blood pressure-oncotic pressure of proteins.
Term
What is filitration? Where does it occur?
Definition
Filitration is moving the liquids from the capparlies to the intersttaial fluid. Occurs in arteries.
Term
What is drainage? Where does it occur?
Definition
Drainage moves liquids from the interstial fluid to the the cappraliies. Occurs in veins.
Term
when blood pressure is greater than oncotic pressure of proteins, what happens?
Definition
Filitration
Term
When blood pressure is below oncotic pressure of proteins, what happens?
Definition
Drainage
Term
True or False; Diameter of arteriole changes flow rate into capillaries
Definition
True
Term
True or false;The weaker force determines the DIRECTION of flux.
Definition
False; the dominant force does.
Term
True or false; The difference between the two forces
determines the MAGNITUDE (how much volume) of flux
Definition
True
Term
What are the 2 major imbalances of filtration and drainage?
Definition
Edema and tissue hypoxia
Term
What is edema?
Definition
accumulation of fluid in the interstitial area
Term
What is tissue hypoxia?
Definition
not enough filtration leading to insufficient oxygenation of the tissues. Can lead to necrosis and gangrene
Term
What are the 5 causes of Edema?
Definition
Increased capillary blood pressure
Reduced plasma protein osmotic pressure
Increased capillary permeability
Increased tissue osmotic pressure
Obstruction of lymphatic ducts
Term
What controls blood pressure for a short term?
Definition
Nervous system
Term
What 3 things controls blood pressure long term?
Definition
Fluids shifting across capillaries, kidneys, hormones.
Term
True or false; sympathetic and parasympathetic work individually, not at the same time.
Definition
True
Term
Which blood vessel has muscles that can be stimulated by nerves?
Definition
arterioles
Term
Explain how blood pressure is regulated to control heart rate.
Definition
Chemoreceptors and strech receptors in aortic and cartiod body detect a change and go to the cardiovascular center in the medulla. The medulla uses the parasymp to decrease heart rate by decreasing BP. The symp is used to increase heart rate through the adrenal gland by increasing BP.
Term
Both sympathetic and parasympathetic influence the pacemaker, but the symp can go the ______.
Definition
Myocardium (heart muscle)
Term
Explain how the parasympathetic regulates high blood pressure through the heart?
Definition
decreases heart rate, decreases cardiac output, and then decreases blood pressure.
Term
Explain how the sympathetic regulates low BP through the heart?
Definition
heart rate increases and cardiac output increases, which increases BP. OR contractile strength of heart increases , stroke volume increases, and then cradiac output increases and BP increases.
Term
Explain sympathetic regulates low BP through the veins?
Definition
Increase vasconstriction, increase venous return, increase stroke volume,, increase caridac out put, and increase BP
Term
Explain sympathetic regulates low BP through the arterioles?
Definition
Increase vasoconstriction, increase total peripheral resistance, and increase BP.
Term
Orthostatic hypertension
Definition
the pooling of the blood when you come from lying down from standing up, which makes your BP very low for a breif period of time
Term
Explain how the kidneys decreases high BP/
Definition
High BP leads to a higher filitration rate in kindeys, leading to lower plasma and blood volumes, which leads to decrease venous pressure, decrease venous return, decrease end-diastolic volume, decrease stroke volume, and decrease cardiac output, reducing BP.
Term
How does ADH influence BP and blood volume?
Definition
When blood pressure falls, the strech receptors decerease (aortic and cardiac receptors don’t produce many AP), ifnormation going to neurosectory cells and they release ADH, ADH constircts BP and raises BP back to normal. ADH allows for more water absorbtion, which allow for a expanded blow volume.
Term
How does renin influence BP and blood volume?
Definition
The kidney flow of blood into the glomerulus diminsihes, the JGA cells release renin and causes angio to be relased. Angio also constricts the blood vessel and raises the BP.Angiotensin can cause the secretion of aldosterone from the adrenal cortex. It insets sdoium pumps in the distal tubes, which means more salt is in the blood (water comes with salt), so blood volume increases.
Term
What is xylem? What two transport tubes does it use?
Definition
transports water and minerals via Tracheids and Vessel Elements
Term
What is phloem? What two transport tubes does it use?
Definition
transports sugars via Sieve Tubes with Companion cells
Term
Xylem is made from ____ cells, phloem is made from _____
Definition
dead; living
Term
Phloem is a _____ wall with ____ ____; xylem is a _____ wall with ____.
Definition
thin;sieve plates thick;ligin
Term
Which vascular tissue in plants has two-way flow?
Definition
Phloem
Term
Which vascular tissue in plants had cells with end perforations?
Definition
Phloem
Term
What is an apoplast and symplast? Which is regulated and which isn't?
Definition
Apoplast goes along walls and between cells, and symplast goes through cells. Both transport water and minerals to cells. Symplast is regulated, apoplsat is not.
Term
What prevents apolostic movement in plants? Why?
Definition
Caspian Strip; It has suberin (water-repellant)
Term
Positive root pressure causes what?
Definition
Dew on plants
Term
How is water moved up plants?
Definition
Leaves create suction pressure to move water upwards.
Term
What is adhesion?
Definition
H2o sticking to walls of plants.
Term
What is cohesion?
Definition
H2O sticking to each other because of hydrogen bonds.
Term
What is tension?
Definition
Pull casued by evaporation.
Term
What is the evaporation-cohesion model? Explain the three steps
Definition
Depicts transpiration in the xylem. (1) Evaporation causes tension on water, (2) water stickts to xylem walls through adhesion, (3) water moves upwards through cohesion.
Term
Explain transpiration?
Definition
Evaporation in the leaf produces tension in the surface film of water on the moist-walled mesophyll cells, thus pulling water and dissolved minerals up the xylem from the root
Term
True or false; water cannot move laterally
Definition
False; it can.
Term
What is the source-sink model?
Definition
The source-sink model transports nutrients from the source to the pholoem and then these substances will flow to an area of use (known as the sink). Source is production of sugar.
Term
What is translocation? What transport vessel does it use?
Definition
Movement of sugars to various parts of the plant. Sieve tubes in phloem
Term
True or false; translocation needs ATP
Definition
True
Term
Translocation proceeds in ___ ____ in the stem, although in a single sieve tube it goes only ___ ___.
Definition
both directions; one way
Term
True or false; sugar moves apolostically
Definition
False; symplastically.
Term
Do we have a bulk flow system in plants? if so, where?
Definition
Difference in solute concentration between sources and sinks allows a difference in pressure potential along sieve tubes, resulting in bulk flow
Term
Explain the translocation process?
Definition
Source cells pump sugar into sieve elements
Water from xylem enters sieve elements by osmosis
This raises pressure here
Pressure forces sap away toward lower pressure areas
In Sink area, water leaves for xylem by osmosis
In sink area, sugar leaves for plant cells
Term
What are the sources of bulk flow for xylem and phloem
Definition
xylem--transpiration from leaves.
phloem--active transport of sugar at source.
Term
What are the sites of bulk flow for xylem and phloem?
Definition
xylem--dead vessel elements
phloem--living sieve tube
Term
What is the pressure of the gradient in xylem and phloem
Definition
negative for xylem, positive for phloem.
Term
Explain why the heart is more at rest than it is active?
Definition
Coronary circulation feed the heart muscles during diastole. This occurs when the heart is at rest.
Term
What is electrical syncytium?
Definition
The heart cell that beats the fastest imposes its rhythm on the others when they touch each other.
Term
3 Effects of sympathetic stimulation on stroke volume of the heart?
Definition
Increase relaxation and contraction rate and heightened contraction
Term
Which circulatory system has low blood pressure?
Definition
Open
Term
What is hemolymph? Where is it found?
Definition
Blood and Interstitial Fluid are the same. Found in open circulatory systems.
Term
Vasodiliation ______ cappilary pressure. Vasoconstriction _____ cappilary pressure.
Definition
increases; decreases.
Term
What is Starling's Law of the Heart?
Definition
The more you fill the end diastolic volume, the more the heart will eject blood
Term
In order for a vessel to be a capillary, what MUST ir have?
Definition
basement membrane.
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