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Biology 101 terms
Harshman's terms to know for 1st exam
121
Biology
Undergraduate 1
09/08/2011

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Term
Genetics
Definition
a key basis of modern biology
Term
Evolution
Definition
the key concept of biology
Term
Physiology
Definition
how animals function
Term
Ecology
Definition
how the organism exist in populations, communities and ecosystems
Term
Prokaryote
Definition
a type of cell containing no membrane enclosed nucleus nor other membrane enclosed organelles
Term
Eukaryotic cell
Definition
a type of cell with a membrane around the nucleus and membrane enclosed organelles
Term
Archaea and bacteria
Definition
prokaryotic
Term
DNA
Definition
the hereditary material in all cells; giant molecule with many repeated subunits
Term
It carries information to make RNA which is the related molecule that can provide codes to make proteins
Definition
DNA
Term
DNA makes ______ that can code for protiens
Definition
RNA
Term
Evolve
Definition
a population has changed in genetic composition after natural selection
Term
Scientific Method
Definition
Generating a hypothesis; testing the hypothesis; and drawing a conclusion
Term
How much of our cells are composed of water?
Definition
70-95%
Term
Isotopes
Definition
elements that have the same number of protons and behave the same in chemical reactions, but they have a different number of neutrons
Term
oxygen, nitrogen, carbon and hydrogen
Definition
four elements that form the main components of biological molecules
Term
Covalent Bonds
Definition
are produced by electron sharing between molecules
Term
Methane
Definition
non-polar
Term
Water
Definition
polar
Term
Ionic bonds
Definition
the transfer of electrons can bond atoms together
Term
Hydrogen bonds
Definition
weak bonds important in holding DNA strands together and giving protiens their shape
Term
chemical reactions
Definition
do not create or destroy matter; only rearrange it in various ways
Term
solution
Definition
a liquid consisting of a uniform mizture of two or more substances
Term
solvent
Definition
dissolving agent
Term
solute
Definition
the substance dissolved by the dissolving agent
Term
What is an average human pH?
Definition
7.4
Term
at what pH can a human not survive
Definition
7.0 and lower or 7.8 and higher
Term
Primary structure
Definition
the sequence of amino acids that make up a protein
Term
secondary structure
Definition
the pattern of a protein folding back on itslf
Term
tertiary structure
Definition
the overall shape of a protein; caused by R group interactions
Term
quaternary structure
Definition
some proteins interact with other proteins; collagen
Term
the four types of protien structures
Definition
[image]
Term
DNA and RNA
Definition
two types of nucleic acids
Term
scanning electron microscope (SEM)
Definition
focuses a beam of electrons to study the detailed architecture of cell surfaces
Term
transmission electron microscope (TEM)
Definition
used to study the details of internal structure; based on a beam going through a thin slice of a cell
Term
light microscopes
Definition
can be used to study living organisms
Term
differential interference contrast microscopy
Definition
amplifies differences in density making cells almost three dimensional
Term
plasma membrane
Definition
the membrane of the cell
Term
plant cells
Definition
have a rigid cell wall and chloroplasts where photosynthesis occurs; they do NOT have lysosomes or centrioles
Term
ribosomes
Definition
make proteins for use in the cells and export; polypeptide (protein) synthesis
Term
free ribosomes
Definition
are found in the cytoplasm
Term
bound ribosomes
Definition
are attached to the endoplasmic reticulum
Term
nucleus
Definition
primary role is to maintain the DNA and pass it on to daughter cells during cell division, to code the proteins that are made by ribosomes
Term
organelles
Definition
are surrounded by membranes and often connected by vesicles (sacs made of membrane)
Term
Endomembrane System
Definition
this system of membranes connects the nuclear envelope, endoplasmic reticulum, Golgi apparatus, lysosomes, vacuoles and plasma membrane.
Term
functions of endomembrane system
Definition
allows for coordination of organelle function and separates the organelles into separate functional compartments
Term
(ER)
Definition
Endoplasmic Reticulum
Term
smooth ER
Definition
does not have ribosomes
Term
rough ER
Definition
has ribosomes
Term
smooth ER functions
Definition
lipid synthesis; detoxification in liver cells; calcium ion storage
Term
compounds made by smooth ER
Definition
lipids (including phospholipids), and steroids
Term
metabolize
Definition
detoxify; incapacitate
Term
rough ER functions
Definition
synthesis of membrane lipids and proteins, secretory proteins, and hydrolytic enxymes; formation of transport vesicles
Term
Golgi apparatus
Definition
modification and sorting of macromolecules; formation of lysosomes and transport vesicles
Term
Endocytosis
Definition
is a machinery for cellular receiving and shipping; receptor-mediated
Term
Lysosomes (in animal cells & some protists)
Definition
digestion of ingested food, bacteria, and a cell's damaged organelles and macromolecules for recycling
Term
Tay-Sachs disease
Definition
lipid metabolism impaired interferring with cellular metabolism; Ashkenazi Jews
Term
Vacuoles
Definition
digestion (food vacuole); storage of chemicals and cell enlargement (central vacuole); water balance (contractile vacuole)
Term
peroxisomes
Definition
(not part of endomembrane system) diverse metabolic processes, with breakdown of toxic hydrogen peroxide by-product
Term
Why are peroxisomes not apart of the endomembrane system?
Definition
because they grow larger by incorporating proteins made primarily in the cytosol and do not bud off from it at all
Term
Mitochondria
Definition
conversion of chemical energy in food to chemical energy of ATP
Term
What is an energy harvesting organelle in plants?
Definition
chloraphil
Term
both mitochondria & chloplasts what?
Definition
evolved by endosymbiosis & are bacteria descendants
Term
Microfilaments, Intermediate filaments, & Microtubules
Definition
protein fibers that serve as structual support for organelles and provide for cell mobility
Term
microfilament
Definition
also called actin filaments; composed of globular proteins called actin; form a 3-D network just inside the plasma membrane that help define cell shape; also are involved in cell movement
Term
intermediate filament
Definition
are made of different fibrous protiens that coil around each other; serve in cell shape and to anchor organelles; can come and go as does the keratin which is the outer layer of skin
Term
microtubule
Definition
straight hollow tubes of globular proteins; play a role in cell division, shape, and act as tracks along which organelles move mobilized by motor proteins, and cells themselves move via these
Term
integrins
Definition
important extracellular matrix protien; spans the membrane attaching to the proteins connected to the microfilaments of the cytoskelton
Term
functions of integrins
Definition
integrate; influence cell behavior; direct development; modulate gene expression
Term
cell junctions
Definition
communication between cells; binding of cells in tissues
Term
tight junctions
Definition
plasma membranes are pressed tightly together and knit tightly together by protiens; they form a seal and prevent the leakage of molecules; (digestive tract)
Term
anchoring junctions
Definition
act like rivets holding cells together; found in skin and heart
Term
gap junctions
Definition
are channels that allow small molecules to flow through protein lined pores; common in embryos for developmental coordination
Term
cell walls
Definition
(in plants, fungi, and some protists) support and protection; binding of cells in tissues
Term
chloroplasts
Definition
(in plants and some protists) conversion of light energy to chemical energy of sugars
Term
cytoskeleton
Definition
(microfilaments, intermediate filaments, & microtubules) maintenance of cell shape; anchorage for organelles; movement of organelles within cells; cell movement (crawling, muscle contraction, bending of cilia and flagella)
Term
extracellular matrix
Definition
(in animals) support; regulation of cellular activities
Term
osmosis
Definition
the diffusion of water across a membrane
Term
osmosis
Definition
the diffusion of water across a membrane
Term
osmosis
Definition
the diffusion of water across a membrane
Term
tonicity
Definition
the ability of a surrounding solution to cause a cell to gain or lose water
Term
isotonic
Definition
when there is no net gain or loss of water
Term
hypertonic
Definition
when there is a net lack of water
Term
hypotonic
Definition
when too much water comes in and the cell can burst
Term
osmoregulation
Definition
the control of water balance
Term
which cell type is better off under hypotonic conditions?
Definition
plant
Term
wilting is caused by _______ conditions?
Definition
hypertonic
Term
transport proteins
Definition
can facilitate diffusion of a specific solute across membranes
Term
aquaporin
Definition
a protein channel that facilitates the entry of water into plant cells, kidney cells, red blood cells; a single one allows the entry of 3 billion water molecules per second
Term
Who, when and how were aquaporins discovered?
Definition
Peter Agree won the 2003 Nobel Prize in Chemistry for the discovery of aquaporins; he started out working on Rh blood antigens
Term
Exocytosis
Definition
the cell uses this to export bulky items such as protiens or polysaccharides (tear production)
Term
Endocytosis
Definition
the process of importing items into cells
Term
Cholesterol
Definition
is necessary for membranes and to make other steroids; circulates in the blood in low-density lipoprotein (LDLs)
Term
kinetic energy
Definition
the energy of motion; moving objects can perform work by transferring motion to other objects
Term
potential energy
Definition
energy that matter possesses
Term
chemical energy
Definition
the potential energy available for release in a chemical reaction
Term
ATP
Definition
the major source of potential & chemical energy used for kinetic energy in cells
Term
exergonic reaction
Definition
releases energy; generates energy (photosynthesis)
Term
endergonic reaction
Definition
makes energy
Term
metabolism
Definition
every working cell produces thousands of exergonic and endergonic reactions; this is the total of these cellular reactions
Term
metabolic pathway
Definition
a series of chemical reactions that builds or breaks down complex molecules
Term
cellular respiration
Definition
slowly releases the metabolic potential of energy stored in sugar
Term
Which macromolecule is most similar to ATP?
Definition
DNA, because of the adenine group. DNA differs in that it only has one phosphate for ATP's three
Term
Cellular work
Definition
driven by energy produced by ATP to ADP where the terminal phosphate is released (three types: Chemical, Mechanical, & Transport)
Term
Enzymes
Definition
proteins (usually, although some RNAs can act in a similar manner) that perform some chemical reaction for cellular function
Term
enzyme function
Definition
they speed up chemical reactions by lowering energy barriers; there is an energy barrier to be overcome for a chemical reaction for relatively stable chemical structures
Term
Enzyme inhibitors
Definition
a chemical that interferes with an enzymes activity is called an inhibitor
Term
competitive inhibitor
Definition
blocks the active site of the enzyme
Term
non-competitive inhibitor
Definition
blocks the allosteric site of the enzyme (shape changer)
Term
feedback inhibition
Definition
if a cell produces more of a product than it needs, the product may act as an inhibitor of an enzyme early in the pathway
Term
A pathway
Definition
is a series of enzyme steps that produces products for cells
Term
ibuprofen
Definition
inhibits production of a "pain messenger"
Term
antibiotics (penicillin)
Definition
inhibits bacterial cell wall production
Term
malathion
Definition
irreversible nerve function inhibition
Term
nerve gases
Definition
irreversible inhibition of an enzyme that plays a role in nerve impulses
Term
photosynthesis
Definition
takes place in the chloroplast, the cell uses glucose to produce energy the output is oxygen
Term
redox reaction
Definition
the gain of electrons is reduction and the loss of electrons is oxidation (reduction & oxidation always go together, therefore "redox")
Term
stages of cellular respiration
Definition
three main pathways: 1.) Glycolysis, 2.) Pyruvate oxidation & the citric acid cycle, 3.) Oxidative phosphorylation
Term
glycolysis
Definition
breaks glucose up into two molecules with 3 carbons each (pyruvate) ; the process captures energy as ATP molecules; takes place in the cytoplasm
Term
Pyruvate oxidation & the citric acid cycle
Definition
completes the breakdown of glucose to carbon dioxide; takes place in the mitochondria; generates energy (note the "symbolic amount" of ATP from this step)
Term
Oxidative phosphorylation
Definition
the main function of the 1st two steps (glycolysis, citric acid oxidation) is to supply electrons for this step; takes place in the mitochondria to an electron transport chain embedded in the inner membrane; produces a lot of ATP
Term
glycolysis - substrate level phosphorylation
Definition
an enzyme transfers a phosphate group from a substrate molecule directly to ADP
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