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BIOL 224
Pituitary Hormones
14
Biology
Undergraduate 2
12/06/2010

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Term

TSH

Definition

Thyroid Stimulating Hormone

gland: anterior pituitary

stimulated by: TRH

target: thyroid gland

effect: secretion of thyroid hormones (T3,T4, bind to target cell mitochondria and increase the rate of ATP production)

regulation: hypothalmic release of TRH inhibited by increased serum T3 levels

Term

ACTH

Definition

Adrenocorticotropic Hormone

gland: anterior pituitary

stimulated by: neural stimulation from hypothalamus and CRH

target: suprarenal cortex - zona fasciculata

effect: secretion of glucocorticoids (cortisol, corticosterone, increases blood sugar, F.A. metabolism, glucogenesis, decreases inflammatory response - sympathetic)

regulation: hypothalmic release of CRH inhibited by increased serum glucocorticoids

Term

FSH

Definition

Follicle Stimulating Hormone

gland: anterior pituitary

stimulated by: GnRH

target: follicle cells of ovaries and nurse cells of testes

effect:

  female- secretion of estrogen, follicle develpment

  male- stimulation of sperm maturation

regulation: hypothalmic release of GnRH inhibited by increased serum testosterone and estrogen levels

Term

LH

Definition

Lutenizing Hormone

gland: anterior pituitary

stimulated by: GnRH

target: follicle cells of ovaries and interstitial cells of testes

effect:

  female- ovulation, formation of corpus luteum, secretion of progesterone

  male- secretion of testosterone regulation:

Term

PRL

Definition

Prolactin

gland: anterior pituitary

stimulated by: PRF (prolactin releasing factor)

target: mammary glands

effect: production milk

regulation: PRF and PIH

Term

GH

Definition

Growth Hormone

gland: anterior pituitary

stimulated by: GH-RH

target: all cells

effect: growth, protein synthesis, lipid mobilization and catabolism

regulation: GH-RH and GH-IH

Term

MSH

Definition

Melanocyte Stimulating Hormone

gland: anterior pituitary (pars intermedia)

stimulated by: ?

target: melanocytes

effect: increased melanin synthesis in epidermis

regulation: MSH-IH

Term

ADH

Definition

Anti Diuretic Hormone

gland: posterior pituitary

stimulated by: Angeotensin II, osmoreceptors in hypothalamus in the supraoptic nucleus

target: kidneys

effect: reabsorbtion of H2O, increase in BV and BP, decreased blood osmolality

regulation: none

Term

OXT

Definition

Oxytocin

gland: posterior pituitary stimulated by: pressure and touch of the uterus, cervix and nipple, sent by the paraventricular nucleus

target:

  female- uterus, mammary glands

  male- vas deferens, prostate gland

effect:

  female- labor contractions, milk ejection

  male- contractions of vas deferens and prostate gland

regulation: none

Term

TRH

Definition
Thyrotropin Releasing Hormone secreted by the hypothalamus stimulates increased secretion of TSH
Term

CRH

Definition
Corticotropin Releasing Hormone released by hypothalamus causing increased secretion of ACTH
Term

glucagon

Definition

-released by alpha cells of the pancreas

-raises blood glucose levels by increasing the rate of glycogen breakdown and glucose release by the liver

-secreted in response to decline in serum glucose levels

Term

insulin

Definition

-produced by the beta cells of the pancreas

-lowers blood glucose levels by increasing uptake by most cells in the body and increasing glycogen synthesis in the liver and skeletal muscles

-secreted in response to elevated serum glucose

Term

GnRH

Definition

released by hypothalamus to increase LH and FSH secretion by the anterior pituitary

 

inhibited by testosterone and estrogen

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