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BIOL 205
Final Study Cards
359
Physiology
Undergraduate 2
07/24/2011

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Term
The watery medium that surrounds a cell is known as
Definition
extracellular Fluid
Term
Place these terms in the typical sequence in which they appear in the scientific process: experimental data, theory, model, observation, hypothesis, replication
Definition
observation, hypothesis, experimental data, replication, model, theory
Term
What type of graph would be best to display the data on the finishing times of the 10 fastest horses in a single race at the Kentucky Derby?
Definition
Bar Graph
Term
The term polar is used to describe molecules because
Definition
there are at least two distinct ends of the molecule regarding electron position
Term
A nucleotide consists of
Definition
a five-carbon sugar, a nitrogenous base, and a phosphate group
Term
Which of the following is NOT a membrane lipid?
Definition
cholesterol, phospholipids, and sphingolipids
Term
Saturation occurs when
Definition
a group of carrier proteins is operating at its maximum rate
Term
A harmful substance that the liver produces when metabolizing fatty acids is
Definition
ketone bodies
Term
A placebo is
Definition
a drug or treatment that is expected to have no pharmacological effect
Term
When energy is released during catabolism, it is temporarily trapped in high energy bonds or electrons of certain compounds. Which of the following is NOT associated with carrying energy?
Definition
DNA
Term
Homeostasis is the ability of the body to
Definition
quickly restore changed conditions to normal
Term
The following is a list of several levels of organization that make up the human body: tissue, cell, organ, molecule, organism, organ system. Smallest to largest...
Definition
molecule, cell, tissue, organ, organ system, organism
Term
An exergonic chemical reaction
Definition
converts molecules into molecules that have less free energy; releases energy as the reaction progresses
Term
The induced-fit model of enzyme activity states that
Definition
neither the substrate nor the products can bend to bind with the enzyme; the enzyme must bend to allow interaction
Term
Metabolism is a term that describes
Definition
all chemical reactions that take place within an organism
Term
You conduct an experiment on twenty 18-year-old male subjects to see how various intensities of exercise influence heart rate. Which of the following is/are considered an independent variable?
Definition
intensity of exercise
Term
The number of mitochondria in skeletal muscle cells is ______ adipose (fat) cells.
Definition
greater than
Term
An allosteric modulator binds to
Definition
a region of the enzyme other than the active site
Term
Which of the following is NOT considered an essential element for a living organism?
Definition
mercury
Term
Which body fluid compartment contains high levels of K+, large anions, and proteins?
Definition
intracellular fluid
Term
Passive transport refers to a process that requires
Definition
no cellular energy
Term
A free radical is a
Definition
molecule with an unpaired electron
Term
Facilitated diffusion and active transport differ in that
Definition
ATP is necessary for active transport, but not for facilitated diffusion
Term
Fruits and vegetables are a good source of antioxidants.
Definition
True
Term
The first law of thermodynamics states that
Definition
the total amount of energy in the universe is constant; energy can neither be created nor destroyed
Term
A competitive inhibitor binds to
Definition
the active site
Term
The inside of a resting cell is slightly negative relative to the outside. This is an example of
Definition
chemical disequilibrium
Term
The reactions where fats are broken down into glycerol and fatty acids are called
Definition
lipolysis
Term
Peroxisomes
Definition
use an enzyme to destroy H2O2 that is toxic to the cell
Term
Coenzymes are
Definition
derived from vitamins; organic molecules; organic cofactors
Term
All of these statements about carbohydrates are true except one. Identify the exception.
Definition
Glycogen is important both for energy storage and to provide structure for cells
Term
The ion that plays a key role in initiating electrical signals in neurons is
Definition
Na+
Term
Fick's law of diffusion states that the rate of diffusion across a membrane is
Definition
proportional to concentration gradient, surface area, and membrane permeability.
Term
Which of the following is a common feature of soluble proteins?
Definition
noncovalent interaction
Term
All of the structures listed below are involved in storage, EXCEPT
Definition
lysosomes; secretory vesicles; storage vesicles; peroxisomes.
Term
Voltage-gated (voltage-dependent) channels and antiport carriers are both types of
Definition
transporters
Term
Hyposmotic solutions
Definition
have lower concentrations of solutes than hyperosmotic solutions
Term
All of the following are types of mediated transport except one. Identify the exception.
Definition
simple diffusion
Term
Cholesterol is
Definition
a precursor to steroid hormones; a structural component of cell membranes
Term
There are 10 cloned horses, born on the same day, with identical chromosomes. They are each subjected to the same physical training regimen, but given daily injections of different concentrations of a particular vitamin. They all run the same race. You set up a graph to explore a relationship between race finish time and vitamin dose. Which type of graph is best to explore a relationship between race finish time and vitamin dose?
Definition
scatter plot
Term
The term meaning programmed cell death is
Definition
apoptosis
Term
Since the widespread adoption of the Pap test, deaths from cervical cancer have dropped
Definition
70%
Term
The atomic number of an element directly or indirectly indicates
Definition
the placement of the atom in the periodic table of the elements; the number of electrons in one atom; the number of protons in one atom
Term
A physician basing clinical decisions on primary research published in biomedical literature is doing __________ medicine.
Definition
evidence-based
Term
Enzymes act by
Definition
increasing the likelihood that a reaction will start; lowering the activation energy of a reaction; binding to the reactants and putting them in favorable positions to react
Term
The components of ribosomes are formed by
Definition
nucleoli
Term
Which group of elements makes up more than 90% of the body's mass?
Definition
O, C, H
Term
The study of body function in a disease state is
Definition
pathophysiology
Term
For each NADH molecule that moves through the electron transport system, what is the potential yield of ATP molecules?
Definition
2.5
Term
Which of the following is a buffer zone between the outside world and most of the cells of the body?
Definition
extracellular fluid
Term
Functions of epithelia include all of the following EXCEPT
Definition
storing energy reserves
Term
The alpha-helix and pleated sheet are examples of the __________ structure of a protein.
Definition
secondary
Term
The type of protein found in gap junctions is the
Definition
connexin
Term
Microtubules
Definition
form cilia that aid in cell movement; are hollow, filamentous structures; are the largest cytoplasmic fibers; are composed of tubulin
Term
You are interested in learning more about Parkinson's disease, a neurological disorder that primarily affects motor function. What is the best source to begin your investigation?
Definition
PubMed
Term
Water will always move from __________ areas to __________ areas, if there are no impermeable barriers.
Definition
hyposmotic, hyperosmotic
Term
In a simple endocrine reflex, the endocrine cell is the
Definition
sensor; integrating center
Term
Synergism occurs when
Definition
hormones working together produce a larger effect than predicted
Term
Inositol triphosphate
Definition
binds to the calcium channel of the endoplasmic recticulum; is involved in the release of calcium into the cytosol
Term
Which is NOT a basic method of cell-to-cell communication?
Definition
mechanical signals
Term
Cyclic AMP activates
Definition
protein kinase A
Term
The most significant difference between a paracrine and an autocrine is
Definition
the cell that responds to it
Term
Each of the following statements concerning peptide hormones is true except one. Identify the exception.
Definition
Peptide hormones in the bloodstream are always bound to carrier proteins.
Term
Diacylglycerol is produced from
Definition
phosphatidylinositol bisphosphate
Term
The binding of lipophilic messengers, such as steroid hormones, to their receptors triggers
Definition
gene transcription
Term
The pituitary hormone that stimulates milk production by the mammary glands is
Definition
prolactin
Term
Receptor molecules on the surface of a cell
Definition
may allow a particular ligand to bind; determine that cell's response
Term
The intracellular effector in chemical signaling is often
Definition
protein kinase
Term
The posterior pituitary gland secretes
Definition
ADH
Term
The increasingly forceful uterine contractions that lead to childbirth are an example of
Definition
positive feedback
Term
One intracellular calcium-binding protein is
Definition
calmodulin
Term
Negative feedback
Definition
stabilizes the variable being regulated
Term
Which type of feedback promotes homeostasis?
Definition
negative
Term
When steroid hormones bind to their receptors,
Definition
gene transcription may start or stop
Term
When calcium becomes available inside a cell, it comes from
Definition
intracellular storage; extracellular fluid
Term
The pituitary hormone that controls hormone synthesis and release from the thyroid gland is
Definition
TSH
Term
Second messenger molecules directly
Definition
change the regulation of ion channels; increase intracellular calcium concentration; change enzyme activity
Term
The majority of hormones in the body are
Definition
peptide hormones
Term
When stimulated by a particular hormone, there is a marked increase in the activity of G proteins in the membrane. The hormone is probably
Definition
a peptide
Term
After a hormone has exerted its effects, it typically
Definition
is inactivated or removed from the blood
Term
When adenylyl cyclase is activated,
Definition
cAMP is formed
Term
Down-regulation may allow a target cell to
Definition
decrease its number of receptors for a ligand
Term
What by-product results during the production of nitric oxide?
Definition
citrulline
Term
Why do some normal cells fail to respond to a chemical signal?
Definition
Some cells lack the necessary receptors
Term
Hormones acting through signal transduction pathways elicit a __________ response compared to hormones that produce genomic effects.
Definition
faster
Term
Steroid hormones are synthesized in the __________ of the cell.
Definition
smooth endoplasmic reticulum
Term
Which of the following is NOT a method of hormone action?
Definition
control of electrical signaling pathways
Term
When a catecholamine or peptide hormone binds to receptors on the surface of a cell,
Definition
a second messenger appears in the cytoplasm
Term
When adenylyl cyclase is activated,
Definition
cAMP is formed
Term
The most important factor determining which type of receptor a signal molecule will bind to is
Definition
the lipid solubility of the ligand
Term
Usually, cytokine binding activates
Definition
JAK kinase
Term
The most complex endocrine responses involve the
Definition
hypothalamus
Term
Both insulin and glucagon are peptide hormones that target liver cells. The response of the target cells to each of these two hormones is opposite. This information implies that
Definition
the two hormones bind to different cell surface receptors; each of the two hormones uses a different second messenger
Term
Exocrine glands, smooth muscles, and cardiac muscles are controlled by the
Definition
autonomic nervous system
Term
Which brain area is considered to be the integrating center for homeostasis?
Definition
hypothalamus
Term
Pain from one area of the body, such as in cardiac ischemia, can be felt in another area, such as the neck and left shoulder; this is called
Definition
referred pain
Term
The afferent and efferent axons together form the
Definition
peripheral nervous system
Term
Glial cells
Definition
provide structural and metabolic support; guide neurons during growth and repair; help maintain homeostasis of the brain's extracellular fluid
Term
The collection of axons that carries information between the central nervous system and the peripheral effectors is called the
Definition
nerve
Term
A blind spot in the retina occurs where
Definition
photoreceptors are absent, as the optic nerve leaves the eye
Term
The enteric nervous system is a network of neurons that function in controlling
Definition
digestion
Term
The ciliary muscle helps to
Definition
control the shape of the lens
Term
Myelin is formed by
Definition
Schwann cells; oligodendrocytes
Term
The sensory receptors of the semicircular canals are located in the
Definition
ampullae
Term
Louder noises result in __________ action potentials in the sensory neuron.
Definition
more frequent
Term
Tonic receptors
Definition
are activated by parameters that must be continuously monitored by the body; are slowly adapting receptors; are proprioreceptors, for example
Term
A sudden flash of bright light would
Definition
cause contraction of the pupillary constrictor muscles
Term
Cell bodies of sensory neurons are located in
Definition
dorsal root ganglia
Term
Excitatory neurotransmitters of the CNS usually act by opening __________ channels.
Definition
Na+
Term
The falling phase of the action potential is due primarily to
Definition
K+ flow out of the cell
Term
A viral infection involving the vestibular nuclei may result in
Definition
a sense of dizziness
Term
Chemicals such as histamine, prostaglandins, serotonin, and substance P
Definition
activate nociceptors by lowering their activation threshold
Term
Photoreceptors secrete the neurotransmitter
Definition
glutamate
Term
The primary purpose of the auditory ossicles is
Definition
to amplify vibration
Term
The portions of a neuron that extend off of the roughly spherical cell body are usually collectively called
Definition
processes
Term
Detailed understanding of the cellular basis of signaling in the nervous system has lead to good understanding of consciousness, intelligence, and emotion.
Definition
False
Term
Which stimulus opens more sodium channels in photoreceptors?
Definition
dimmer light
Term
When a rod cell in the eye is stimulated by light,
Definition
the intracellular level of cGMP decreases
Term
Cold receptors have been shown to respond also to
Definition
menthol
Term
If the sodium pump in the membranes of the photoreceptors were blocked,
Definition
blindness would result
Term
The brain region that is identifiable by its folds and grooves is the
Definition
cerebellum; cerebrum
Term
Cerebrospinal fluid is produced by the
Definition
choroid plexus
Term
Branches that sometimes occur along the length of an axon are called
Definition
collaterals
Term
With the exception of olfaction, all sensory pathways first travel to the __________, which acts as a relay and processing station.
Definition
thalamus
Term
Declarative memories are stored in cortical areas of the __________ lobes.
Definition
temporal
Term
The vitreous chamber of the eye
Definition
helps to stabilize it and gives physical support to the retina
Term
These glial cells act as scavengers
Definition
microglia
Term
The multiple thin, branched structures on a neuron whose main function is to receive incoming signals are the
Definition
dendrites
Term
Which is NOT housed in the medulla oblongata?
Definition
centers for control of eye movement
Term
Autonomic motor neurons are subdivided into the
Definition
sympathetic and parasympathetic divisions
Term
The Nernst equation predicts
Definition
the membrane potential resulting from permeability to a single ion
Term
The structure that overlies the organ of Corti is the
Definition
tectorial membrane
Term
The term axonal transport refers to
Definition
vesicle transport of proteins and organelles down the axon
Term
What does the Goldman-Hodgkin-Katz equation take into account that the Nernst equation does NOT?
Definition
the permeabilities of the ions
Term
When voltage-gated K+ channels of a resting neuron open,
Definition
K+ leaves the neuron
Term
Language and verbal skills tend to be __________ side of the brain of right-handed people.
Definition
concentrated on the left
Term
Which is a system that influences motor output, according to Larry Swanson?
Definition
behavioral state
Term
The pons develops from the
Definition
hindbrain
Term
Gustatory neurons are stimulated by taste cells for
Definition
salty; sour
Term
Neurotransmitters are released from the
Definition
axon terminals
Term
The motor end plate is
Definition
a folded area of muscle cell membrane with ACh receptors clustered at the top of each fold
Term
The presence of two peripheral efferent neurons in a pathway is typical of the __________ division.
Definition
autonomic
Term
The division of the autonomic nervous system that prepares the body for intense levels of activity and stress is the
Definition
sympathetic division
Term
__________ postganglionic sympathetic neurons secrete __________ onto their target cells.
Definition
Most, norepinephrine
Term
Which functions are controlled through the autonomic nervous system?
1. blood pressure
2. heart rate
3. water balance
4. temperature regulation
Definition
1, 2, 3, 4
Term
Which area is NOT normally considered to be an autonomic control center?
Definition
amygdala
Term
The adrenal medulla is important to the sympathetic branch of the autonomic nervous system because
Definition
it is considered a modified sympathetic ganglion; it releases epinephrine and norepinephrine directly into the blood; it is a source of catecholamines
Term
Which of the following has its cell body in the ganglion?
Definition
postganglionic neuron
Term
Epinephrine and norepinephrine that are released from the adrenal glands affect target tissue for a longer period of time than the same substances released from neurons at their peripheral receptors. Why?
Definition
There are no enzymes to break down epinephrine and norepinephrine in the blood and very little in peripheral tissues.
Term
Striated muscles are so-called because of a repeating pattern of light and dark bands. One repeating unit of the banding pattern is called a
Definition
sarcomere
Term
In the arm, the biceps brachii is a flexor whereas triceps brachii is an extensor. Which of the following statements is TRUE?
Definition
Theses muscles are an example of antagonistic muscles; The biceps brachii is the primary muscle responsible for movement of the hand and forearm towards the shoulder
Term
Each myosin head has
Definition
a binding site for an actin molecule; a binding site for an ATP molecule; the ability to swivel when powered by ATP
Term
When acetylcholine is released into the neuromuscular junction,
Definition
the muscle membrane depolarizes, creating an end-plate potential (EPP); action potentials are triggered, which lead to activation of the contraction cycle; it binds to receptors that allow Na+ and K+ ions to cross the sarcolemma
Term
The tension generated in a muscle fiber is directly proportional to the
Definition
number of crossbridges formed
Term
The H zone contains
Definition
thick filaments
Term
The power stroke begins when
Definition
the inorganic phosphate and ADP are released from the myosin
Term
The purpose of transverse tubules is to
Definition
rapidly conduct action potentials to the interior of the muscle fiber
Term
Regulation of cross-bridge formation is accomplished by
Definition
troponin; calcium ions; tropomyosin
Term
Muscle fatigue arises primarily from failure in
Definition
excitation-contraction cycle
Term
Motor neurons are sometimes inhibited by
Definition
Golgi tendon organs
Term
Which reflex is NOT controlled by the brainstem?
Definition
urination
Term
Most reflexes are regulated by
Definition
negative feedback
Term
The sensory fibers of the muscle spindle organs synapse onto
Definition
alpha motor neurons
Term
The reflex that prevents a muscle from exerting too much tension is the
Definition
tendon reflex
Term
After stretching an intrafusal fiber, the next event is
Definition
an increase in action potentials along the associated sensory neuron
Term
The effector in a reflex is the
Definition
muscle or gland
Term
Spinal interneurons prevent muscle antagonists from interfering with an intended movement by
Definition
the process of reciprocal inhibition
Term
Most reflex movements are integrated by
Definition
the spinal cord
Term
Cortisol, the catecholamines, and growth hormone do all of the following, EXCEPT
Definition
enhance deposition of fat in adipose tissue
Term
With endurance training, muscle mitochondria increase in
Definition
size; number
Term
In resistance exercise, such as strength training, muscles rely heavily on __________ energy production.
Definition
anaerobic
Term
The advantage of anaerobic metabolism is
Definition
rapid ATP production
Term
Fat stores are used for energy only after muscles have depleted their carbohydrate energy stores.
Definition
False
Term
The role of phosphocreatine is to
Definition
transfer energy
Term
Glycolytic metabolism is also known as
Definition
anaerobic metabolism
Term
The largest metabolic reserves for the average adult are stored as
Definition
triglycerides
Term
Hormones that increase in concentration in the plasma during exercise include
Definition
cortisol; catecholamines
Term
The hepatic portal vein carries blood away from the
Definition
digestive tract
Term
Myocardial cells can generate action potentials spontaneously because they have
Definition
unstable ion channels
Term
The driving force for blood flow is a(n) __________ gradient.
Definition
pressure
Term
The depolarization of the pacemaker action potential spreads to adjacent cells through
Definition
gap junctions
Term
As blood vessel length increases,
Definition
flow decreases; resistance increases
Term
The term myogenic indicates that the heart muscle is the source of
Definition
the electrical signal that triggers heart contraction
Term
The action potential in a cardiac contractile cell causes
Definition
opening of L-type calcium channels
Term
The flattening of the action potentials of myocardial contractile cells, called the plateau phase, is due to a combination of increasing Ca2+ __________ and decreasing K+__________.
Definition
influx, efflux
Term
Which parameters are associated with increased resistance?
Definition
reduced flow
Term
Stretching a myocardial cell
Definition
allows more Ca2+ to enter; increases the force of contraction
Term
The purpose of having valves in the cardiovascular system is to
Definition
ensure that blood flows in one direction
Term
During the plateau phase of the action potentials of myocardial contractile cells, which ion(s) is/are crossing the membrane?
Definition
Na+; K+
Term
Differences between arterioles and metarterioles include the fact that arterioles
Definition
have a continuous smooth muscle layer in their walls
Term
If cardiac output increases and resistance in arterioles does NOT change, what happens to arterial blood pressure?
Definition
increases
Term
Compared to arteries, the velocity of flow of the blood through the capillaries is
Definition
much slower
Term
Osmotic pressure resulting from presence of plasma proteins in blood is called __________ pressure.
Definition
oncotic; colloid osmotic
Term
The mean arterial pressure (MAP) is important because
Definition
it represents the driving pressure for blood flow
Term
Angiostatin and endostatin may be useful in the treatment of
Definition
cancer
Term
When the baroreceptor reflex is triggered by a decline in blood pressure,
Definition
cardiac output increases; sympathetic activity increases
Term
The difference between the systolic and diastolic pressures is called the
Definition
pulse pressure
Term
The integrating center for neural control of blood pressure resides in the
Definition
medulla oblongata
Term
Myogenic autoregulation means that
Definition
stretched smooth muscle in a blood vessel constricts reflexively
Term
Reactive hyperemia is triggered by
Definition
local accumulation of paracrines due to reduced blood flow
Term
Blood pressure is determined by
Definition
measuring the force exerted by blood in a vessel
Term
The process of fibrinolysis
Definition
dissolves clots
Term
The primary stimulus for the release of erythropoietin is
Definition
hypoxemia; low oxygen levels in the tissues
Term
The carrier protein that transports absorbed iron through the blood is
Definition
transferrin
Term
Which of the following is/are vasoconstrictors?
Definition
serotonin; thromboxane A2
Term
Thrombopoietin is produced in the
Definition
liver; kidney
Term
Each red blood cell is shaped as a biconcave disk. This allows it to
Definition
change its shape to squeeze through narrow openings; shrink or swell slightly in response to osmotic conditions
Term
The intrinsic pathway of coagulation is activated by the
Definition
activation of proenzyme exposed to collagen
Term
A hematocrit is used to indicate
Definition
the packed cell volume; the ratio of red blood cells to the total blood volume
Term
Under normal circumstances, aged and damaged erythrocytes are broken down by the
Definition
spleen
Term
Tissue factor is released in the
Definition
extrinsic pathway
Term
Red blood cell production is regulated by the hormone
Definition
erythropoietin
Term
Most excess iron in the body is
Definition
eliminated in the urine
Term
The extrinsic pathway of coagulation is activated by the
Definition
release of tissue factor by a damaged endothelium
Term
Dalton's law states that
Definition
in a mixture of gases like air, the total pressure is the sum of the individual partial pressures of the gases in the mixture
Term
Type II alveolar cells
Definition
secrete a chemical known as surfactant
Term
A typical value for intrapleural pressure is __________ mm Hg
Definition
-3
Term
When alveolar pressure is equal to atmospheric pressure, air flows into the lungs
Definition
false
Term
Total cross-sectional area __________ with each division of the airways
Definition
allow rapid diffusion of gases through their thin membranes
Term
Alveolar ventilation refers to the
Definition
movement of air into and out of the alveoli
Term
Boyle's law states that gas volume is
Definition
inversely proportional to pressure
Term
Air moves into the lungs because
Definition
the gas pressure in the lungs is less than outside pressure
Term
The lungs are enclosed in __________ membranes
Definition
pleural
Term
An increase in Pco2 would cause
Definition
the bronchioles to dilate and the systemic arterioles to dilate
Term
Pulmonary ventilation refers to the
Definition
movement of air into and out of the lungs
Term
According to the law of LaPlace, when comparing two alveoli lined with fluid, pressure in the one with the __________ diameter will be greater
Definition
smaller
Term
The actual sites of gas exchange within the lungs are
Definition
alveoli
Term
Surfactant
Definition
helps prevent the alveoli from collapsing
Term
Air moves out of the lungs because
Definition
the volume of the lungs decreases with expiration
Term
Most of the oxygen transported by the blood is
Definition
bound to hemoglobin
Term
A molecule that blocks the activity of carbonic anhydrase would
Definition
cause an increase in blood pH
Term
Most of the carbon dioxide in the blood is transported as
Definition
bicarbonate ions
Term
Hypoxia resulting from fluid accumulation in the alveoli that cannot be corrected by oxygen therapy can lead to
Definition
adult respiratory distress syndrome
Term
The expiratory neurons control the __________ muscles, whereas the inspiratory neurons control the __________ muscles
Definition
abdominal and internal intercostal, diaphragm and external intercostal
Term
The partial pressure of oxygen in arterial blood is approximately __________ mm Hg
Definition
100
Term
High carbon dioxide concentration in body fluids is called
Definition
hypercapnia
Term
The chloride shift occurs when
Definition
bicarbonate ions leave the red blood cells
Term
In the medulla oblongata, the nucleus tractus solitarius contains the __________ of neurons
Definition
dorsal respiratory group
Term
The process by which dissolved gases are exchanged between the blood and interstitial fluids is
Definition
diffusion
Term
Protective reflexes of the lungs include
Definition
coughing; bronchoconstriction
Term
The lung pathology most likely to result from certain kinds of heart disease is
Definition
pulmonary edema
Term
An increase in the level of carbon dioxide in the blood will
Definition
increase the rate of breathing
Term
Chronic hypoxia
Definition
increases 2,3-DPG production in blood; can be caused by anemia
Term
Which of the following would make the oxygen-hemoglobin curve shift right?
Definition
increased H+ concentration
Term
Blocking afferent action potentials from the chemoreceptors in the carotid and aortic bodies would interfere with the brain's ability to regulate breathing in response to all EXCEPT which of the following?
Definition
changes in blood pressure
Term
The most important chemical regulator of respiration is
Definition
carbon dioxide
Term
At a Pco2 of 70 mm Hg and normal temperature and pH, hemoglobin is __________% saturated with oxygen
Definition
over 90
Term
The Hering-Breuer reflex
Definition
prevents overexpansion of the lungs
Term
Urea is
Definition
passively reabsorbed in the proximal tubule
Term
The typical pattern for molecules absorbed by Na+-dependent transport involves this: an apical __________ and a basolateral __________
Definition
symport protein, facilitated diffusion carrier
Term
A glomerulus is
Definition
a "knot" of capillaries that lies within the Bowman's capsule
Term
Which of the following statements about autoregulation is NOT true?
Definition
Myogenic response is the intrinsic ability of vascular smooth muscle to respond to pressure changes
Term
The amount of plasma that filters into the nephrons is approximately __________ of the total volume
Definition
1/5
Term
In a normal kidney, which of the following conditions would cause an increase in the glomerular filtration rate (GFR)?
Definition
a decrease in the concentration of plasma proteins in the blood
Term
The Bowman's capsule and glomerulus make up the
Definition
renal corpuscle
Term
Blood flow through the kidney includes a feature seen in only a few organs. What is it?
Definition
portal system
Term
The portion of the nephron that attaches to the collecting duct is the
Definition
distal tubule
Term
The primary function of the proximal tubule is
Definition
reabsorption of ions, organic molecules, and water
Term
Which is NOT a kidney filtration barrier?
Definition
juxtaglomerular apparatus
Term
An obstruction in a glomerulus would affect the flow of blood into the
Definition
efferent arteriole
Term
Ions directly regulated by the kidney include all EXCEPT which of the following?
Definition
OH-
Term
Urine is produced by the
Definition
kidney
Term
Place the following blood vessels that carry blood to and within the kidney in the order in which blood passes through them
1. afferent arteriole
2. efferent arteriole
3. glomerulus
4. peritubular capillary
Definition
1, 3, 2, 4
Term
The force for glomerular filtration is the
Definition
blood pressure in the glomerular capillaries
Term
If blood flow through the afferent arterioles increases,
Definition
stretch reflexes trigger vasoconstriction to reduce the flow
Term
Which structure is NOT part of the blood circulation through the kidney?
Definition
loop of Henle
Term
Kidneys respond relatively __________ to changes in blood volume
Definition
slowly
Term
Angiotensin II
Definition
causes the synthesis and release of aldosterone from the adrenal cortex; stimulates thirst; causes widespread vasoconstriction throughout the body
Term
The hormone ADH
Definition
stimulates water conservation at the kidneys
Term
The two organ systems that work together to regulate most aspects of the body's water balance are
Definition
urinary and cardiovascular
Term
Most body water is located
Definition
inside cells
Term
When a body is dehydrated, water in the urinary bladder
Definition
will still be expelled from the body in the urine
Term
Atrial natriuretic peptide
Definition
Inhibits the release of ADH
Term
Kidneys regulate
Definition
water loss
Term
Juxtaglomerular cells in the nephron secrete
Definition
renin
Term
The hormone that directly controls water excretion by the kidneys is
Definition
ADH
Term
The primary route for water loss from the body is the __________ system
Definition
urinary
Term
Cell volume (and therefore cell function) in most cells is dependent upon careful regulation of
Definition
osmolarity of extracellular fluid
Term
The hormone that regulates water excretion by the kidneys
Definition
increases water permeability in only certain portions of the kidney tubules
Term
Stimuli for the activation of the RAAS pathway include
Definition
low blood pressure in arterioles in the nephron; a decrease in fluid flow through the distal tubule
Term
The primary route for ion loss from the body is the __________ system
Definition
urinary
Term
Thirst is
Definition
triggered by increased osmolarity; controlled by centers in the hypothalamus
Term
When baroreceptors in the carotid and aortic bodies register increased blood pressure, this results in
Definition
inhibition of ADH secretion
Term
Osmoreceptors depolarize after they __________ in response to __________ plasma osmolarity
Definition
shrink, increased
Term
Aldosterone
Definition
promotes sodium retention in the kidneys
Term
Intestinal crypts
Definition
increase the surface area of the mucosa of the small intestine; produce new cells for the mucosa of the small intestine
Term
Mechanical digestion refers to
Definition
the enzymatic breakdown of food
Term
Which of the following is an accessory organ of digestion?
Definition
pancreas
Term
Rugae, plicae, and villi are all features that accomplish
Definition
an increase in surface area
Term
The myenteric plexus is
Definition
a network of neurons
Term
G cells of the stomach secrete
Definition
gastrin
Term
The __________ is a significant site of absorption of water and electrolytes, but NOT of nutrients
Definition
large intestine
Term
Chief cells secrete
Definition
pepsinogen
Term
Which of the following is the sequence of layers from the lumen to the outer wall of the digestive tract?
Definition
mucosa, submucosa, muscularis externa, serosa
Term
Adipocytes secrete the hormone
Definition
leptin
Term
During the fasting state, the energy stores of the __________ become the major source of glucose for the whole body
Definition
liver
Term
During the absorptive state,
Definition
the liver forms glycogen
Term
The most practical way to estimate a person's basal metabolic rate is to measure it when the person is
Definition
resting after a 12-hour fast
Term
Lipoproteins that carry mostly cholesterol and phospholipids from peripheral tissues to the liver are called
Definition
high-density lipoproteins (HDLs)
Term
D cells in the islet of Langerhans secrete
Definition
somatostatin
Term
The nutrients that yield the most energy per gram when metabolized are
Definition
fats
Term
The alpha cells of the pancreas produce
Definition
glucagon
Term
The feeding and satiety centers are located in the
Definition
hypothalamus
Term
Cholesterol is a precursor for the synthesis of
Definition
estradiol; aldosterone; progesterone
Term
Cortisol secretion peaks between __________ and __________
Definition
early morning, noon
Term
All of the hormones secreted by the adrenal gland play a major role in growth and metabolism
Definition
false
Term
The C cells of the thyroid gland produce
Definition
calcitonin
Term
Thyroid hormone contains the mineral
Definition
iodine
Term
The pituitary hormone that triggers the release of thyroid hormone from the thyroid gland is
Definition
TSH
Term
Somatostatin is another name for
Definition
growth hormone-inhibiting hormone
Term
The action of a hormone on a target cell involves effects on target cell
Definition
receptor proteins; nonreceptor proteins
Term
The adrenal medulla produces
Definition
catecholamines
Term
Cells of the mononuclear phagocyte system include
Definition
macrophages and monocytes
Term
C-reactive protein is a type of
Definition
acute-phase protein
Term
Lymphocytes and plasma cells
Definition
mediate the acquired immune response; are found primarily in lymphoid tissue
Term
Antibiotics are drugs that destroy or inhibit the growth of
Definition
bacteria
Term
Leukocytes recognize molecules that are unique to pathogens; thus, the molecules are
Definition
pathogen-associated molecular patterns
Term
Cytokines function by
Definition
acting as messengers for growth and activity of other cells
Term
The largest lymphoid tissue(s) is/are the
Definition
spleen
Term
Opsonins function by
Definition
marking or tagging pathogens so phagocytes can find and ingest them
Term
Swelling and soreness of the lymph nodes indicate that
Definition
immune cells are fighting infection
Term
Autoimmune diseases are an example of a/an __________ response by the immune system
Definition
incorrect
Term
A zygote with the genotype YO will
Definition
die
Term
Menstruation is triggered by a drop in the level(s) of
Definition
estrogen and progesterone
Term
The chorionic villi
Definition
increase the surface area available for exchange between the placenta and the maternal blood
Term
The small paired glands at the base of the penis that produce a lubricating secretion are the
Definition
bulbourethral glands
Term
Mitotic divisions in germ cells
Definition
The answer depends on gender
Term
Indifferent gonads develop into testes under the influence of:
A) peptide or protein hormones
B) estrogens
C) androgens
D) none of the above
Definition
none of the above
Term
When allowed to develop, the Mullerian ducts become the
Definition
fallopian tubes, uterus, and upper vagina
Term
Interstitial cells produce
Definition
androgens
Term
Sperm cannot fertilize an egg until they
Definition
undergo capacitation
Term
The role of the pituitary hormone FSH in males is to
Definition
initiate sperm production in the testes
Term
The structure that transports the ovum to the uterus is the
Definition
fallopian tube
Term
Aromatase
Definition
is an enzyme that converts testosterone to estradiol
Term
The erectile tissue that surrounds the urethra is the
Definition
corpus spongiosum
Term
The product of the SRY gene is
Definition
testis-determining factor
Term
The average length of the menstrual cycle is
Definition
28 days
Term
Egg and sperm cells have
Definition
23 chromosomes
Term
Sperm production occurs in
Definition
the seminiferous tubules
Term
The embryo forms from the
Definition
inner cell mass of the blastocyst
Term
Periodic pulsatile secretion of GnRH appears to be important in
Definition
preventing down-regulation of GnRH receptors
Term
Which of the following hormones is NOT produced by the placenta?
Definition
luteinizing hormone
Term
Meiosis of one cell results in production of
Definition
four gametes if male, one if female
Term
During meiosis, the chromosome number is halved
Definition
during the first meiotic division
Term
Emission is defined as
Definition
movement of sperm into the urethra
Term
Gametes are produced by
Definition
gonads
Term
X-linked genes are expressed
Definition
more often in males
Term
The fold of skin that covers the tip of the penis is the
Definition
prepuce
Term
The corpus luteum in a nonpregnant woman usually lasts about
Definition
12 days
Term
Polyspermy in humans results in
Definition
a nonfunctional zygote
Term
The hormone that is the basis for a pregnancy test is
Definition
human chorionic gonadotropin (hCG)
Term
The cervix is
Definition
the neck of the uterus
Term
The principal hormone secreted by the corpus luteum is
Definition
progesterone
Term
________ decreases ovarian follicle sensitivity to FSH
Definition
Anti-Mullerian hormone
Term
In the condition known as cryptorchidism
Definition
the testes fail to descend into the scrotum
Term
Sister chromatids
Definition
contain twice the normal amount of DNA
Term
The surge in LH that occurs during the middle of the ovarian cycle triggers
Definition
ovulation
Term
The structure that carries sperm from the epididymis to the urethra is the
Definition
ductus deferens
Term
Which form of contraception allows fertilization but prevents implantation?
Definition
IUD
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