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Bio Test #2
the second bio test
76
Biology
Undergraduate 2
10/28/2012

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Term
Why does diffusion work for single cell organisms?
Definition
They need LOTS of surface area to get food from diffusion.
Term
How do multicellular organisms get nutrients?
Definition
You have to "carry your own pond and control it (homeostasis)"
Term
Negative Feedback loops
Definition
-signal to brain to change temp when gets to hot or too cold
-homeostasis
Term
Positive Feedback loops
Definition
-amplification
Term
Breaks in homeostasis
Definition
-fever
-after a work out
-hibernation
Term
Bioenergetics
Definition
-how an organism uses its energy
-heat
-growth
-reproduction
Term
Catabolic reaction
Definition
break down molecules-- release energy
eg cellular respiration
Term
Anabolic reaction
Definition
build molecules-- use energy
eg building, growing, and reproduction
Term
How to measure catabolic and anabolic reactions:
(metabolic rate)
Definition
calorimetry
food consumption (messy and difficult)
oxygen consumption
Term
Ectotherms:
Definition
body temp is same as environment, cold blooded
Term
Endotherms:
Definition
generate heat internally, often kept constant
(mammals, birds, and many dinosaurs)
Term
Energy budgets-
Definition
bigger mammal uses more for metabolic regulation
ectotherm uses no energy for heat
Term
What are the phases of Mitosis
Definition
Prophase
Metaphase
Anaphase
Telophase
Term
Mitosis:
Definition
regular cell division
Term
Meiosis:
Definition
special cell division that creates gamates
Term
Chromosomes:
Definition
centromere:
histones:
chromatid:
Homologous pairs:
Term
Other than mitosis-- what goes on in the cell?
Definition
G1, S and G2!
G1- cell grows
S- DNA replicates
G2- cell grows some more
Term
Prophase:
Definition
-chromosomes condense
-nuclear envelope disappears
-centrosomes move to opposite poles
-spindles start to form
Term
Metaphase:
Definition
-chromosomes line up on equator
-centrosomes attach to centromeres
Term
Anaphase:
Definition
-centromeres divide
-one chromosome to two chromotids
-chromosomes pulled towards opposite poles
Term
Telophase:
Definition
-cell divides
-spindles disintegrate
-nuclear envelope reforms
Term
Cytokinesis:
Definition
-divides cell
Animals: actin fibers pinch off cell
Plants: cell wall reforms in between new cells
Term
Cancer--
Definition
uncontrolled division of cells caused by a genetic mutation
normal cells controlled by:
stay in G1 phase
normal cells are mortal
p53 gene tells cell to kill itself
Term
HeLa cells
Definition
Henrietta Lacks 1951
cells without p53 gene that are immortal
for polio research
Term
Oncogenes
Definition
-where cancer mutation starts because those usually monitor the cells
Term
mutations caused by---
Definition
radiation, carcinogens, and problems in DNA replication
Term
Angiogenesis:
Definition
the process of developing a system of arteries and veins to supply the tumor
Term
Metastasis
Definition
the spread of cancer to another region of the body
the protein allow the cells to detach
Term
Chemo
Definition
the administration of cell damaging chemicals to destroy cancer cells
Term
How to combat cancer?
Definition
chemo, radiation and surgery
Term
What is meiosis
Definition
- 1/2 chromosomes
- sexual reproduction
- 4 haploid cells
Term
Prophase I/2:
Definition
chromosomes condense,
nuclear membrane disappears,
centrioles replicate and move to poles
Term
metaphase I/2:
Definition
pairs of homologous chromosome move to equator,
held by spindle fibers
Term
Anaphase I/2:
Definition
chromosomes pulled to either pole
spindle fibers pull apart
Term
Telophase I/2:
Definition
chromosomes reach poles
cell starts to divide
cytokinesis occurs
Term
phases of meiosis
Definition
prophase I
metaphase I
anaphase I
telophase I
prophase II
metaphase II
anaphase II
telophase II

makes 4 haploid cells
Term
Mitosis discovered by:
Definition
Oscar Hertwig
Term
Meiosis discovered by:
Definition
Walther Flemming
Term
Diploid dominant
Definition
animals
Term
haploid dominant
Definition
some fungi
Term
alternation of generation
Definition
ferns
Term
Karyotype
Definition
picture of your chromosomes
Term
deletion
Definition
removal of a segment
Term
duplication
Definition
double a region
Term
inversion
Definition
flips a region
Term
translocation
Definition
stuff from one chromosome to a different chromosome
Term
polyploidy and types
Definition
many sets of chromosomes
triploid and tetraploid
Term
anueploidy
Definition
abnormal # of chromosomes
trisomy 2n+1 (down syndrome)
monosomy 2n-1
Term
Non-disjunction Meiosis I
Definition
- don't divide correctly
Term
Barr bodies
Definition
Murray Barr, inactivate one X chromosome in female cell
tortoise shell cats
Term
Dosage compensation and the Lyon Hypothesis (should be a theory now)
Definition
one X chromosome is inactivated
Term
Kleinfelter's syndrome
Definition
XXY
sexual immaturity
breast swelling
affects neurodevelopment
Term
Jacobs Syndrome
Definition
XYY
extra male
tall
acne
low fertility
Term
XXX syndrome
Definition
XXX
tall
thin
menstrual irregularity
Term
Turner Syndrome
Definition
XO
no barr bodies
short
web-necked
sexually undeveloped
doesn't affect neural development
Term
Androgen insensitivity
Definition
X linked
extra female
XY
internal testes
Term
pseudohermaphrodism
Definition
autosomal recessive
look female then become functional male
Term
Law of segregation
Definition
Alleles separate into individual gamates
Term
Law of independent assortment
Definition
genes assort independently
Term
Thomas Hunt Morgan
Definition
studied fruit flies mutations
formed sequence of genetics
Term
sex influenced
Definition
like the wings in dragons
Term
Watson and Crick
Definition
Term
Rosalind Franklin
Definition
took pictures that helped watson and crick
Term
DNA replication terms
Definition
fork
replication bubble
Term
Meselson and Stahl
Definition
figured out how replication works
semiconservative hypothesis
Term
DNA polymaerase
Definition
adds nitrogenous bases to replication bubble
Term
Okazaki fragments
Definition
fragments on lagging strand
Term
Primer
Definition
gets lagging strand ready for polymerace
Term
Ligase
Definition
connects Okazaki fragments
Term
helicase
Definition
unzips the genes
Term
topoismerase
Definition
keeps DNA from bunching up
Term
Transcription vs translation
Definition
nucleic acid to nucleic acid to protein
DNA to mRNA to protein
Term
Crick and central dogma
Definition
dna transfered in one direction
Term
Beadle and Tatum
Definition
one gene one enzyme
-------gene A ---> gene B --X--> gene C
protein--> protein---X--> protein---> product
Term
Genetic Code
Definition
-read continuously
-codons are nucleotide triplets
-code does not overlap
-code is degenerate

UNIVERSAL
Term
different types of RNA
Definition
mRNA
tRNA
ribosomal RNA
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