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Bio Midterm 3
biomidterm3
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Biology
Undergraduate 2
11/07/2009

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Term
Functional Groups
Definition
groups that when plugged into another molecule, it gives that molecule an added charge or property. functional group is a group of atmos that confers a special property on a carbon-based molecule
Term
Carbohydrates
Definition
organic molecules that always contain carbon, oxygen, and hydrogen and that in many instances contain nothing but carbon, oygen, and hydrogen
Term
Organic Chemistry
Definition
a branch of chemistry devoted to the study of compounds that have carbon as their central element
Term
Hydrocarbon
Definition
molecules where the only elements present are hydrogen and carbon
Term
Why is carbon central to life
Definition
Most biological molecules are built on a carbon framework
Term
Four groups of organic compounds
Definition
Carbohydrates, lipids, proteins, and nucleic acids
Term
Monosaccharide
Definition
the building blocks of carbohydrates. monomers of carbohydrates collectively referred to as simple sugars. examples are glucose
Term
Disaccharide
Definition
when you put two monosaccharides together
Term
Starch
Definition
an example of a polymer
Term
Polymer
Definition
a large molecule made up of many similar or identical subunits
Term
Monomer
Definition
a small molecule that can be combined with other similar or identical molecules to make a polymer
Term
Examples of monosaccharides
Definition
monomers such as Glucose and Fructose
Term
Examples of amino acids
Definition
monomers such as Arginine and leucine
Term
Examples of nucleotide
Definition
monomers such as sugar, phosphate, base in combination
Term
Examples of polysaccharides
Definition
Polymers such as starch, glycogen, cellulose
Term
Examples of polypeptides or proteins
Definition
polymers such as A- and B- cahins of insulin
Term
Examples of nucleic acids
Definition
polymers such as DNA or RNA
Term
Four types of complex carbohydrates
Definition
Starch, Glycogen, Cellulose, and Chitin
Term
Starch
Definition
complex carbohydrate found in plants; it exists in the form of such foods as potatoes, rice, carrots, and corn. these starches serve as the main form of carbohydrate storage in plants
Term
Glycogen
Definition
serves as the primary form of carbohydrate storage in animals.
Term
Cellulose
Definition
a rigid, complex carbohydrate contained in the cell walls of many organisms.
Term
Chitin
Definition
a complex carbohydrate that forms the external skeleton of the arthropods-all insects, spiders, and crustaceans
Term
Lipids
Definition
a class of molecules whose defining characteristic is that htey do not readily dissolve in water. lipids are made of the same things as carbohydrates, but have more hydrogen relative to oxygen
Term
Types of lipids
Definition
triglycerides, phospholipids, steroids, waxes
Term
Triglyceride
Definition
a lipid molecule formed from three fatty acids bonded to glycerol
Term
Fatty acid
Definition
a molecule found in many lipids that is composed of a hydrocarbon chain bonded to a carboxyl group
Term
Saturated fatty acid
Definition
a fatty acid with no double bonds between the carbon atoms of its hydrocarbon chain
Term
Monounsaturated Fatty acid
Definition
a fatty acid with one double bond between carbon atoms
Term
Polyunsaturated fatty acid
Definition
a fatty acid with two or more double bonds between carbon atoms
Term
Steroids
Definition
a class of lipid molecules that have, as a central element in their structure, four carbon rings. the thing that separates one steroid from another are the various side chains that can be attached to these rings
Term
Cholesterol
Definition
a steroid molecule that forms part of the outer membrane of all animal cells and that acts as a precursor for many other steroids. male hormone is testosterone and female hormone is estrogen
Term
Phospholipid
Definition
a charged lipid molecule composed of two fatty acids, glycerol, and a phosphate group
Term
Phosphate Group
Definition
a phosphorus atom surrounded by four oxygen atoms
Term
Wax
Definition
can be defined as a lipid composed of a single fatty acid linked to a long-chain alcohol
Term
Types of Proteins
Definition
Enzymes, hormones, transport, contractile, protective, structural, storage, toxins, communication
Term
Monomers of proteins
Definition
amino acids.
Term
Polypeptide
Definition
a series of amino acids linked in linear fashion
Term
Protein
Definition
an extremely diverse group of biological molecules composed of the monomers called amino acids. a large, folded chain of amino acids. this is what a polypeptide chain is called when it folds up in a specific three-dimensional manner
Term
Amino Acids fundamental structural unit consists of
Definition
an amino group and a carboxyl group attached to a central carbon
Term
The thing that differentiates on amino acid from another is...
Definition
the group of atoms that occupies the R or "side-chain" position
Term
How many amino acids are the basis for all proteins in living organisms?
Definition
20
Term
Amino acids are strung together by
Definition
the carboxyl group of one amino acid joining to the amino group of another
Term
First level of structure in a protein
Definition
Primary Structure: simply its sequence of amino acids. Determines everything else about the protein's final shape
Term
Second level of structure in a protein
Definition
Secondary Structure: strucutural motifs, such as the corkscrew-like alpha helix, beta pleated sheets, and the less organized "random coils" are parts of many polypeptide chains, forming their secondary structure
Term
Third level of structure in protein
Definition
Tertiary Structure: these motifs may persist through a set of larger-scale turns that make up the tertiary strucutre of the molecule
Term
Fourth level of structure in protein
Definition
Quaternary Structure: several polypeptide chains may be linked together in a given protein, in this case hemoglobin with their configuration forming its quaternary structure
Term
Lipoproteins
Definition
molecules that are a combination of lipids and proteins. They are transport molecules that amount to a capsule of protein surrounding a globule of fat.
Term
Glycoproteins
Definition
combinations of proteins and carbohydrates.receptors on the surface of cells are likely to be composed of glycoproteins, where the protein would be the "stem" and the carbohydrate owould be the side chain that extend from the stem and serve as binding sites
Term
Building blocks of nucleic acids
Definition
Nucleotides
Term
Deoxyribonucleic Acid (DNA)
Definition
the primary information-bearing molecule of life, composed of two linked cahins of nucleotides
Term
Nucleotide
Definition
A molecule in three parts: a sugar (deoxyribose), a phosphate group, and a nitrogen-containing base
Term
Ribonucleic Acid (RNA)
Definition
a molecule composed of nucleotides that is active in the synthesis of proteins. Functions include ferrying the DNA-encoded instructions to a kind of workbench in the cell, called a ribosome, where proteins are put together
Term
DNA is composed of these three types of component molecules
Definition
Phosphate groups, the sugar deoxyribose, and the bases adenine, thymine, guanine, and cytosine (ATCG)
Term
What links together to form the handrails of the double helix?
Definition
The sugar from one nucleotide links with the phosphate from the next
Term
The complementary bases that link the two rails together are linked by...
Definition
hydrogen bonds
Term
First step in DNA replication
Definition
the joined strands of the double helix unwinds, separating from one another
Term
Second step of DNA replication
Definition
The nucleotides on each of the single strands are then paired with free-floating nucleotides that line up in new, complementary strands
Term
Third step in DNA replication
Definition
is that now both strands of the original double helix are being paired with new strands, which forms the two double helices
Term
Helicases
Definition
enzymes that unwind the double helix, separating its two strands to make the bases on them available for base pairing.
Term
DNA Polymerases
Definition
group of enxymes that move along each strand of the double helix, joining together nucleotides as they are added-one by one-to form new, complementary strands of DNA. they also remove a mismatched nucleotide and replace it with a proper one.
Term
Mutation
Definition
a permanent alteration of a DNA base sequenc
Term
DNA is copied by means of each strand of DNA serving as a ____ for the synthesis of a new, _____ strand
Definition
template, complementary
Term
The DNA gets replicated in this phase of mitosis
Definition
Interphase-S
Term
Mutagens
Definition
substances or things that cause mutations (ex: sunlight, cigarette smoke, carcinogens)
Term
Point Mutations
Definition
a mutation of a single base pair in the genome.
Term
Malignant Tumor
Definition
uncontrolled cell proliferation, impacts adjacent tissues, mitosis will keep occurring and grow uncontrollably, it will invade other parts of your body
Term
Oncogenes
Definition
two classes on proteins that play a big part in cancers
Term
Four levels of proteins
Definition
Primary Structure, Secondary Structure, Tertiary Structure, Quaternary Structure
Term
Polypeptide chains function as proteins only when...
Definition
folded into their proper three-dimensional shape
Term
First step of protein synthesis
Definition
a stretch of DNA is unwound and then Transcription - its message (the order of a's, t's, c's, and g's) is copied onto a a molecule called messenger RNA (mRNA). the segment of mRNA leaves the cell's nucleus, and heads for a ribosome in the cell's cytoplasm, where translation takes place
Term
Ribosome
Definition
an ogranelle, located in the cell's cytoplasm, that is the site of protein synthesis
Term
Second step of protein synthesis
Definition
Translation - Joining the mRNA chain at the ribosome are amino acids, brought there by transfer RNA molecules. The length of messenger RNA is then "read" within the ribosome. A chain of amino acids is linked together in the order specified by the mRNA sequence
Term
Transcription
Definition
The process by which the genetic information encoded in DNA is copied onto messenger RNA
Term
Translation
Definition
the process by which information encoded in messenger RNA is used to assemble a protein at a ribosome.
Term
Differences between RNA and DNA
Definition
RNA is usually single stranded, DNA is structured in two strands. RNA uses uracil instead of thymine. RNA has a ribose sugar, while DNA has a deoxyribose sugar
Term
RNA Polymerase
Definition
this complex of enzymes unwinds the DNA sequence and then strings together the chain of RNA nucleotides that is complementary to it, and then produces the initial RNA chain
Term
Messenger RNA (mRNA)
Definition
a type of RNA that encodes, and carries to ribosomes, information for the synthesis of proteins
Term
The DNA strand that codes for the RNA in transcription is
Definition
the Non-Template, or Coding strand
Term
Codon
Definition
Each coding triplet of mRNA bases
Term
Genetic Code
Definition
the inventory of linkages between nucleotide triplets and the amino acids they code for.
Term
Transfer RNA (tRNA)
Definition
a form of RNA that, in protein synthesis, binds with amino acids, transfers them to ribosomes, and then binds with messenger RNA
Term
mRNA binds to a tRNA by means of
Definition
anticodons
Term
Ribosomal RNA (rRNA)
Definition
found in the cytoplasm and it is a structural component of ribosomes.
Term
mRNA codon that is the usual "start" codon for a polypeptide chain
Definition
AUG
Term
Biotechnology
Definition
the use of technology to control biological processes as a means of meeting societal needs.
Term
Transgenic Organism
Definition
an organism whose genome has stably incorporated one or more genes from another species
Term
Recombinant DNA
Definition
two or more segments of DNA that have been combined by humans into a seququence that does not exist in nature
Term
Restriction enzymes
Definition
proteins derived from bacteria that can cut DNA in specific places and are like molecular scissors
Term
Plasmids
Definition
extrachromosomal rings of bacterial DNA tha can be as little as1,000 base pairs in length. they can replicate independently of the bacterial chromosome, but just as important for biotech's purposes, they can move into bacterial cells
Term
Transformation
Definition
a cell's incorporation of genetic material from outside its boundary. some bacterial cells do this naturally, while others much be induced to perform it by means of chemical treatment.
Term
Recombinant DNA
Definition
two or more segments of DNA that have been combined by humans into a sequence that does not exist in nature
Term
Who is responsible for the technology of recombinant DNA
Definition
Paul Berg 1/2, Walter Gilbert 1/4, Frederick Sanger 1/4
Term
First step in making a protein of interest
Definition
We get human DNA and take a gene of interest by cutting it with a restriction enzyme
Term
Second Step of Making a Protein of Interest
Definition
We take a plasmid and use the same restriction enzyme to snip plasmid
Term
Third Step of Making a Protein of Interest
Definition
Put the human protein of interest in the plasmid to create recombinant DNA
Term
Fourth Step of Making a Protein of Interest
Definition
Transformation is the process that you use to get the recombinant DNA in the new bacteria. you can do this by heat shock or other methods
Term
Fifth Step of Making a Protein of Interest
Definition
you put the bacteria in a peatry dish with a lot of food and space and it will begin to replicate and grow
Term
Polymerase Chain Reaction (PCR)
Definition
a technique for quickly producing many copies of a segment of DNA.
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