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Bio Exam 2 Chapter 8
umd bsci 105 nelson
39
Biology
Undergraduate 2
10/14/2011

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Term
The active site can lower an EA barrier by
Definition
Orienting substrates correctly
Straining substrate bonds
Providing a favorable microenvironment
Covalently bonding to the substrate
Term
what is metabolism
Definition
the totality of an organism chemical reactions , it is the emergent propoerty of life that arisese from interactions between molcules
Term
Metabolic Pathway
Definition
begins with a specific moleule and ends with a products
Term
Catabolic Pathways
Definition
release energy by breaking down complex molecules into smaller compounds ex. cellular respiration breaks down glucose in the presense fo oxygen
Term
Anabolic Pathways
Definition
consume energy to build complex molecules from simpler ones
Term
bioenergetics
Definition
the study of how organisms manage thier energy sources
Term
what is energy
Definition
the capacity to cause change , it exsist in various forms
Term
what are the forms of energy
Definition
kinetic- associated with motion heat-kinetic energy associated with random movement of atoms or molecules potential -energy that matter possess because of its location or structure
Term
what is thermodynamics
Definition
the study of energy transformations
Term
what is the first law of thermodynamics
Definition
The energy of the universe is constant ENERGY CAN BE TRANSFORMED OR TRANSFERED BUT NOT CREATED OR DESTROYED.
Term
What is the second law of thermodynamics
Definition
every energy transfer or transformation increases entropy(disorder) of the universe
Term
what are spontaneous processes
Definition
ones that occur without energy input , they can happen very quickly or very slowly
Term
what does the free energy change of reactions tell us
Definition
whether or not the reactions occurs spontaneously
Term
what is free energy
Definition
the energy that can do work when temp and pressure are uniformed , only negative deltaG is spontaneous
Term
what is equilibrium
Definition
a state of maximum stabilty
Term
what is an exergonic reaction
Definition
proceeds with a net release of free energy and is spontaneous
Term
what is an energonic reaction
Definition
absorbs free energy from its surroundinds and is nonspontaneous
Term
what kinds of work does a cell do
Definition
chemical
transport
mechanical
Term
what is energy coupling
Definition
the use of an exergonic process to drive and endergonic one
Term
this funtions as the cells energy shuttle , what is it
Definition
ATP
Term
what is ATP composed of
Definition
ribose , adenine and three phosphate groups
Term
what are the 3 types of cellular work powered by
Definition
the hydrolosys ATP
Term
what is a catylst
Definition
a chemical agent that speeds up a reactions without being consumed by the reaction.
Term
what is an enzyme
Definition
a catalytic protien
Term
what is activation energy
Definition
teh energy needed to start a chemical reaction
Term
hwo to enzymes catalyze reactions
Definition
by lowering the Ea barrier
Term
what is a substrate
Definition
The reactant that an enzyme acts on is called the enzyme’s
Term
what forms when enzymes bind to substrates
Definition
enzyme -substrate complex
Term
what is an enzymes active site
Definition
the region ont he enzyme where the substrate binds
Term
what does induced fit of a substrate bring about
Definition
of a substrate brings chemical groups of the active site into positions that enhance their ability to catalyze the reaction
Term
what are cofactors
Definition
non protien enzymes helpers that may be inorganic
Term
what is a coenzyme
Definition
organic enzyme
Term
what is a coenzyme
Definition
organic cofactor
Term
this binds to another part of an enzyme causing the enzyme to change shape and makes the active site less effective
Definition
non competative inhibitor
Term
when does allosteric regulation occur
Definition
when a regulatory molecule binds to a protien at one site and affatcs the protien function at another site
Term
what are the most allosterically regulated enzymes made from
Definition
polypeptide subunits
Term
what does the binding of an activator and inhibitors do
Definition
The binding of an activator stabilizes the active form of the enzyme
The binding of an inhibitor stabilizes the inactive form of the enzyme
Term
explain cooperativity
Definition
Cooperativity is a form of allosteric regulation that can amplify enzyme activity
One substrate molecule primes an enzyme to act on additional substrate molecules more readily
Cooperativity is allosteric because binding by a substrate to one active site affects catalysis in a different active site
Term
Feed back inhibition
Definition
the end product of a metabolic pathway shuts down the pathway , prevents a cell from wasting chemical resources by synthesising more products than needed.
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