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BIO 2232
Exam 1
109
Biology
Undergraduate 3
10/08/2012

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Term
SENAG
Definition
Excitatory Neurotransmitters

Some Engines Need Additional Gas (speed up)
Term
GGDES
Definition
Inhibitory Neurotransmitters

Good Girls Don't Eat Sugar (slow down)
Term
SENAG (what are they)
Definition
Substance P, Epinephrine, Norepinephrine, Acetylcholine, Glutamate
Term
GGDES (what are they)
Definition
GABA, Glycine, Dopamine, Endorphins, Serotonin
Term
Acetylcholine
Definition
Excitatory; Affects Parasaympathetic NS, Skeletal muscles, CNS
Term
Acetylcholine's effect on Nicotinic Receptors
Definition
At Neuromuscular junction = skeletal muscle contraction
Term
Acetylcholine's effect on Muscarinic Receptors
Definition
At Parasympathetic; ↓ Heart Rate ↓ BP, ↑ Digestion, pupil constriction
Term
Effect of Organophosphate/Nerve Gas
Definition
inhibits Acetylcholinesterase = more acetylcholine
Term
Alzheimer's is...
Definition
decrease in acetylcholine
Term
Ephinephrine and Norepinephrine are both ______s
Definition
Monoamines
Term
Ephinephrine and Norepinephrine effect ____
Definition
Sympathetic NS
Term
MAO
Definition
Monoamine oxidase; breaks up Monoamines
Term
Curare
Definition
nicotinic blocking agent; prevents skeletal muscle contraction
Term
α1
Definition
affected by epinephrine/norepinephrine
= dilation of iris, blood vessel constriction (increase BP)
Term
α2
Definition
epinephrine/norepinephrine affect it;
at presynaptic membranes
= no more norepinephrine release
Term
α1 agonist causes ?
Definition
pupil dilation if on eye, vasoconstriction if intravenous
Term
β1
Definition
HEART, = ↑ heart rate, ↑ stroke volume
Term
β2
Definition
bronchioles (bronchiodilation), skeletal muscle (increased contraction strength)
Term
β blocker causes ?
Definition
↓ Heart Rate
Term
MAOI = ? and causes ?
Definition
Monoamine Oxidase Inhibitor, prevents breakdown of epinephrine and norepinephrine

= ↑ heart rate, ↑ BP
Term
what might a β2 agonist treat?
Definition
asthma; bronchiodilation
Term
Serotonin
Definition
excitatory; excites muscles, regulates food intake, sex drive, mood, anxiety
Term
What neurotransmitter is LSD most like?
Definition
Serotonin
Term
SSRI
Definition
Selective Serotonin Reuptake Inhibitors
Term
what does an SSRI do?
Definition
increase mood, food regulation, sex drive, less anxiety because more serotonin is in clefts
Term
Dopamine
Definition
Inhibitor; helps mood, digestion, motor control, behavior and emotional reward like drugs/alcohol
Term
Parkinsons is what?
Definition
decreased dopamine; decreased motor control
Term
Glutamate
Definition
excitatory; throughout the entire brain, helps with memory/learning
Term
Substance P
Definition
Excitatory, helps pain transmission to CNS, allows us to know an injury has occured
Term
Endorphins
Definition
Body's own Morphine (runner's high, etc.) and can cause euphoria
Term
What can release endorphines
Definition
exercise, chocolate, chili peppers, acupuncture, meditation, sex
Term
GABA
Definition
inhibitory; allows more Cl- into the postsynaptic neuron = hyperpolarization

Inhibits MUSCLES
Term
decrease in GABA = ?
Definition
Huntington's disease = muscle jerking, seizures
Term
Glycine
Definition
inhibitory; in the CNS spinal cord / brain stem, increases Cl-

helps smooth balance between impulses in spine
Term
Strychnine poisoning = ?
Definition
Glycine Antagonist = convulsions, death
Term
Histimine
Definition
in White Blood Cells, increases cell permeability and alertness
Term
H1 receptors
Definition
throughout body, involved in allergic reactions
Term
H2 receptors
Definition
stomach, responds to histamine released during digestion
Term
Lightly Touch (texture, slow vibrations
Definition
Meissner's Corpuscle
Term
Touch and Light Pressure
Definition
Merkel's Corpuscle
Term
Pain, Temperature, Light touch
Definition
Free Nerve Endings
Term
Deep touch, Deep pressure, fast vibrations
Definition
Pacinian Corpuscle
Term
Sustained Pressure
Definition
Ruffini Corpuscle
Term
Presbyopia
Definition
near point becomes longer as we age because lens loses elasticity
Term
Myopia
Definition
nearsighted; eyeball is too long or lens too strong
Term
Hyperopia
Definition
farsighted; eyeball is too short or lens is lazy
Term
lens changing shape to focus =
Definition
accomodation
Term
for near vision, lens is
Definition
bulgy, spherical
Term
for far vision, lens is
Definition
flat
Term
miosis = ?, what nerve controls?
Definition
constriction of the pupil; CN3 oculomotor
Term
Mydriasis
Definition
dilation of the pupil
Term
Cholinergic drug's affect on eye =
Definition
constriction
Term
Adrenergic drug's affect on eye
Definition
dilation
Term
Adrenergic Antidepressants
Definition
MAOI drugs, nardil, parnate, marplan
Term
Serotonergic Antidepressants
Definition
SSRI, zoloft, prozac, paxil
Term
what is the optic disc
Definition
Term
what nerves are involved in the pupillary response to light
Definition
CN2 (optic)for the sight of the light, and CN3 (oculomotor) for miosis
Term
consensual reflex
Definition
both eyes respond when light is shined
Term
Light in RIGHT EYE, RIGHT CONSTRICTS, light in LEFT EYE, RIGHT CONSTRICTS
Definition
problem with CNIII on the left
Term
light in RIGHT EYE, NEITHER CONSTRICTS,
light in LEFT EYE, BOTH CONSTRICT
Definition
problem with CNII on right
Term
Rods in eye
Definition
night vision, peripheral vision, see gray, sensitive to light/motion

Acts as transducer, changing light energy into action potential energy
Term
Made from Vitamin A, deficiency causes night blindness
Definition
Rhodopsin, in rods
Term
Cones in eye
Definition
color vision, not light sensitive
Term
Iodopsin
Definition
pigment in cones, 3 types - red, blue, green
Term
cone pigments and wavelengths?
Definition
red = long, green = medium, short = blue
Term
In light... (pathway)
Definition
Rhodopsin absorbs photons -->
Cis-retinal isomerizes into trans-retinal -->
Opsin triggers reaction cascade --> signal created in optic nerve --> trans-retinal separates from opsin
Term
In dark... (pathway)
Definition
trans-retinal is converted back to cis-retinal via enzymes --> opsin and cis-retinal enzymatically combine to regenerate rhodopsin
Term
Visual Pathway
Definition
Retina --> Optic Nerve --> Optic Chiasma (cross over)--> Optic tract --> Occipital Lobe (visual cortex)
Term
Auditory Vibration pathway
Definition
Pinna --> Auditory Canal --> Tympanic Membrane --> Ossicles --> Oval Window --> (INNER EAR) --> Perilymph --> Cochlea --> Round Window
Term
Shape of Basilar Membrane
Definition
pitch discrimination
Term
Number of hair cells stimulated
Definition
amplitude discrimination
Term
for balance, cerebellum needs 2/3 of:
Definition
1. eyes, 2. vestibular apparatus, 3. kinesthetic receptors
Term
proprioception
Definition
kinesthetic receptors tell where limbs are in space
Term
static equilibrium
Definition
Urticle and Saccule maintain head position while body is still
Term
dynamic equilibrium
Definition
Semicircular Canal Ampulla detect rotation of head (spinning, shaking, tipping)
Term
Macula
Definition
receptors in Urticle and Saccule, filled with hairs attached to vestibular branch of CNIII (oculomotor)
Term
organ of corti
Definition
this is the receptor for hearing and it is found in the Cochlear Duct of the Cochlea
Term
5 types of chemoreceptors for taste
Definition
sweet, salty, sour, bitter, umami (meaty taste)
Term
pain receptors
Definition
nociceptors
Term
pain associated chemicals
Definition
bradykinin, histamine, prostaglandins
Term
First order neurons
Definition
A-delta (unmyelinated axons), and C-fibers (unmyelinated fibers)

carry to spinal cord
Term
Second Order to Third order neurons
Definition
first orders synapse using substance P or glutamate at second order, these go up spinal cord to the third order at the thalamus
Term
Thalamus's 3 roles:
Definition
Noxious perception (Feel pain)

Localization (where is it?)

Allow you to respond
Term
Deep or Dull pain = ?
Definition
Visceral pain, often inflammation
Term
Sharp rapid pain = ?
Definition
superficial pain
Term
What carries superficial pain?
Definition
a-delta (myelinated) = fast
Term
what carries visceral pain?
Definition
c-fibers (unmyelinated) = slow
Term
Lateral Inhibition = ?
Definition
adjacent neurons by where pain occurred are inhibited so that signal is enhanced and localization is easier
Term
how does aspirin alter pain perception?
Definition
inhibits production of prostaglandins
Term
how do endorphins and enkaphalins alter pain perception?
Definition
inhibit pain TRANSMISSION, work just like Opiate drugs
Term
how do non-pain pathways alter pain perception?
Definition
for ex, touch receptors fire off and therefore decrease the information sent along the pain path. That's why we rub an injury.
Term
Referred Pain
Definition
Visceral pain is felt in superficial areas
Term
alpha waves
Definition
awake, relaxed
Term
beta waves
Definition
awake, attentive/thinking hard
Term
theta waves
Definition
sleep
Term
delta waves
Definition
sleep, deepest and slowest rhythm
Term
role of light on circadian clock
Definition
light INHIBITS melatonin,
Dark STIMULATES melatonin production

these go to hypothalamus to help set the clock
Term
purpose of REM
Definition
reverse learning, memory consolidation, necessary for mental well being
Term
purpose of NREM stage 4
Definition
brain restores itself for whatever is needed for next day,

also motor learning, SKATEBOARD TRICK WHILE SLEEPING
Term
implicit memory
Definition
reflexive, shooting a basketball
Term
explicit memory, and 2 types
Definition
learning facts, abstract (book facts) and episodic (events)
Term
right hemisphere of brain is for:
Definition
art/patterns/music

faces, symbols, emotion in speech
Term
left hemisphere of brain is for
Definition
language / analytics
Term
which hemisphere is usually dominant?
Definition
left
Term
Wernicke's Area
Definition
LEFT SIDE

word recognition/comprehensive; knowing what you are saying or writing/hearing or reading
Term
Broca's Area
Definition
LEFT SIDE

making the words come out of your mouth, if damaged, they know what they want to say but can't say it
Term
Wernicke's analog
Definition
RIGHT SIDE

recognizes symbols, patterns, faces
Term
Broca's analog
Definition
RIGHT SIDE

recognize emotion is speech, like if someone is angry while talking to you
Term
parts of brain involved with memory formation and consolidation
Definition
amydala, hippocampus, prefrontal cortex, temporal lobe
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