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Bio 14
Mendel and the Gene Idea
54
Biology
Undergraduate 1
10/15/2012

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Term
Who was the "father of genetics?" and when did he work?
Definition
Gregor Mendel from the 1860's
Term
What did Gregor Mendel do with peas?
Definition
He controlled whether peas would self fertilize or cross fertilize
Term
What did Gregor Mendel identify?
Definition
Heritable factors (genes) that were passed among generations of pea plants.
Term
True-breeding
Definition
Plants that have had the same characteristics for many previous self-pollinated generations
Term
Hypbrids
Definition
Offspring from cross between two different genotypes.
Term
The three generations
Definition
P (parental) -- true breeding parents
F1 (filial, son") result of cross fertilization of P generation
F2 generation, result of self fertilization of F1 generation
Term
Monohybrid Cross
Definition
Parents differ in only one characteristic
Term
Alleles
Definition
Alternate versions of a gene found at the same locus on homologous chromosomes
Term
Law of Segregation
Definition
Pairs of alleles segregate during gamete formation.
Term
How many alleles of each gene do sperm and egg cells have
Definition
One
Term
How many alleles of each gene do body cells have?
Definition
Two.
Term
Homozygous
Definition
When an organism as a pair of identical alleles
Term
Heterozygous
Definition
When an organism has two different alleles for a trait.
Term
Dominant allele
Definition
The gene that is expressed and represented with a capital letter.
Term
Recessive allele
Definition
The gene that is not expressed and represented with a lowercase letter.
Term
Recessive alleles often code for...
Definition
Non-functional proteins
Term
Dominant is not always...
Definition
the most common in a population (e.g) having freckles is dominant to no freckles)
Term
Symbol for Homozygous
Definition
AA or aa
Term
Symbol for heterozygous
Definition
Aa
Term
Why is dominant not always the most common in a population?
Definition
Only the advantageous characteristics survive natural selection enough to fill out a population.
Term
Punnett Square
Definition
Diagram showing possible allele distribution from fertilization.
Term
Phenotype
Definition
Physical/physiological trait Ex. 1 white: 3 purple
Term
Genotype
Definition
Genetic composition Ex. 1 PP: 3 Pp
Term
Test cross
Definition
Mating a dominant phenotype with a homozygous recessive to see if it is homozygous or heterozygous
Term
Dihybrid Cross
Definition
The crossing of two parents with two different characterisitcs.
Term
Dihybrids
Definition
Individuals heterozygous for two characteristics being followed.
Term
Dihybrid cross
Definition
When true-breeding parents differ in two characteristics.
Term
Law of independent assortment
Definition
Alleles on different chromosomes are inherited independently of one another.
Term
How do you determine the alleles in a gamete?
Definition
The FOIL method.
Term
Multiplication Rule
Definition
To determine the probability of two or more events will occur together, multiply the probability of each separate event.
Term
Addition Rule
Definition
To determine the probability of mutually exclusive events, then add their individual probabilities.
Term
Incomplete Dominance
Definition
Where the F1 hybrids have a phenotype somewhere between those of two parental varieties, due to the dominant trait not being strong enough in a heterozygous genotype.
Term
Does incomplete dominance support the hypothesis that genes are blended?
Definition
No, they are particulate, because the alleles separate to create complete phenotypes in offspring.
Term
Gene coding for protein
Definition
2 C^r allele makes red
1 C^R allele makes pink
2 C^w allele makes white
Term
True or false: Most genes have only two alleles?
Definition
False. Most have multiple, but individuals can only have two alleles.
Term
What is an example of a multiple allele trait?
Definition
Blood type
Term
What are the alleles of blood and how many phenotypes are there?
Definition
1^A, 1^B, i; 4 phenotypes
Term
What are the phenotypes of blood?
Definition
A, B, AB, O
Term
What characteristic of blood cells is determined by the genotype?
Definition
The glycoproteins on the red blood cells.
Term
Codominance
Definition
Where both alleles in a heterozygous genotype are expressed.
Term
What is an example of codominance?
Definition
AB blood type.
Term
Pleiotropy
Definition
A single gene affecting multiple phenotypic characteristics.
Term
What is an example of pleiotropy?
Definition
Sickle-cell allele, which leads to abnormal hemoglobin, as well as paralysis kidney damage etc.
Term
What is strange about a carrier of sickle cell disease?
Definition
They have resistance against malaria as an evolutionary advantage.
Term
Is pleitropy true of most genes?
Definition
Yes.
Term
Epistasis
Definition
The expression of one gene affecting the expression of another.
Term
What is an example of epistasis?
Definition
How a lab's coat color is dependent on the trait that codes for the presence of Melanin.
Term
Polygenetic Inheritance
Definition
Where two or more genes affect a single phenotypic characterisitc.
Term
What is an example of polygenetic inheritance?
Definition
Skin color and height.
Term
What is the difference between polygenetic inheritance and pleiotropy?
Definition
Polygenetic inheritance is multiple genes affecting one phenotypic characteristic and pleotropy is one gene affecting multiple phenotypic characteristics.
Term
What characters are not either-or characters?
Definition
Quantitative characters.
Term
WHat are examples of quantitative characters?
Definition
Skin color and height.
Term
What does a quantitative character indicate?
Definition
Polygenic inheritance.
Term
What is the nature versus nurture debate?
Definition
Whether phenotypes are more influenced by genes or by the environment.
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