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Bio 113 Lecture 2
Meiosis and its role in determining pattern of inheritance
48
Biology
Undergraduate 1
01/16/2013

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Term
a eukaryotic cell where chromosomes exist in pairs. all human somatic cells are this
Definition
Diploid
Term
a cell with only one set of chromosomes
Definition
haploid
Term
what is the diploid chromosome number in humans?
Definition

46

 

2n=46

Term
which cells does mitosis occur in?
Definition
somatic cells
Term
which line does meiosis occur in?
Definition
the germ line
Term
two individual chromosomes that were inherited from different parents are known as?
Definition

homologous pairs

aka homolouges

Term

ture/false

homologues are alike and have identical versions of genes at their corresponding loci?

Definition

false

they are alike but have different versions of genes at some of the corresponding loci

Term
homologous chromosomes replicate to form sister...
Definition
chromatids
Term
i am one of the two identical strands of a new replicated chromosome. what am i?
Definition
a chromatid
Term
 meiosis produces how many gametes and how many chromosomes do they contain?
Definition
meiosis produces 4 gametes and they contain n (diploid) chromosomes
Term
what is the mechanism by which diploid cells produce haploid cells during gamete formation?
Definition
meiosis
Term
how many cell divisions does meiosis involve?
Definition
two
Term
which meiosis am i? my chromosomes replicate and recombination occurs. homologous chromosomes seperate and produce 2 haploid cells?
Definition
meiosis 1
Term

which meiosis is this?

 the chromatids seperate producing four haploid gametes?

Definition
meiosis 2
Term

meiosis 1 which stage?

 

chromosome replicate to form pairs of chromatids but chromosomes have not yet condensed

Definition
Interphase
Term
in which stage of meiosis one does synapsis occur?
Definition

prophase one

 here is where the tetrad forms and crossing over takes place at chiasmata

Term
where does synapsis, crossing over at chiasmata and formation of a tetrad occur?
Definition
prophase 1 of meiosis one
Term
what is synapsis and where does it occur?
Definition
synapsis is unique to mieosis. it is the pairing of homologous chromosomes and occurs in prophase 1 in meiosis 1
Term

true of false?

when chromosomes line up on the metaphase plate in metaphase 1 they are still in tetrads?

Definition

this is true.

the orientation of each tetrad is random

Term

what seperates in Anaphase 1?

 

sister chromatids or homologous chromosomes?

Definition
homologous chromosomes seprate and move towards oppostie poles but sister chromatids remain attached
Term
in telophase and cytokinesis 1 is DNA  replicated?
Definition

No DNA is not replicated

two haploid cells form - chromosomes still double pairs of chromatids but they either have maternal or paternal dna

Term
two BB would be known as?
Definition
homozygous dominant
Term
bb is know as?
Definition
homozygous recessive
Term
in which phase does the nuclei form at opposite poles, cytokenesis occurs and results in four haploid daughter cells (gametes)?
Definition
Meiosis II final phase: Telophase and Cytokinesis
Term
where do meiosis and mitosis occur?
Definition

mitosis in somatic body cells

meiosis in the germ line

Term
compare cell divisions in mitosis and meiosis
Definition

mitosis - 1 cell division

meiosis - 2 cell divisions

Term
compare the products of mitosis and meiosis
Definition

mitosis - 2 identical diploid cells

meiosis - 4 non identical haploid cells

Term
I am also known as reductional division
Definition
meiosis I
Term
I am also known as equational division
Definition
Meiosis II
Term
In somatic cells, chromosomes occur in...
Definition
pairs
Term
chromosome pairs segregate ...............into gametes
Definition
equally
Term
different chromosome pairs assort.....
Definition
independantly
Term
where does the chromsome theory og inheritence state the 'inheritable factors' are located?
Definition
specific positions (loci) on chromosomes
Term
what do genes determine?
Definition
traits
Term
where in particular are genes located on a chromosome?
Definition
a particular locus
Term

true or false?

genes can exist in different forms of alles?

Definition
true.. one on each member of a pair of homologous chromosomes
Term
how many alleles do we inherit from each parent?
Definition
one
Term
how does chromosome behaviour in meiosis explain Mendels Law of Segregation?
Definition

mendels law : 2 forms of alleles present in each parent seperate independantly

 

meiosis: homologous pairs of chromosomes move to opposite poles in anaphase I

Term
How does chromosome behaviour in meiosis explain Mendel's Law of Independant Assortment?
Definition

mendels law: each pair of alleles assorts independantly of each other pair of alleles during gamete formation

 

meiosis : explained by the random way homologous pairs line up on the metaphase plate during meiosis I

Term

learn this Law

 

Law of segregation - the 2 alleles present in each diploid parent seperate independantly (ie. only one is passed to each progeny)

Definition
This is demonstrated in meiosis I as homologous pairs seperate and move to opposite ends of the poles.
Term

Learn this Law too:

Different pairs of alleles assort independantly to produce different combinations in the progeny

Definition
This is demonstrated with the random arrangement of the chromosomes at the metaphase plate in meiosis I
Term

what am i defining?

i am the process of genetic recombination that gives rise to new combinations of linked genes

Definition
cross over
Term
which phase does crossing over take place in?
Definition
the pachytene phase of Prophase I
Term
how does the crossing over process begin and what else is involed?
Definition

the process begins with synapsis - the pairing of homologous chromosomes

the synaptonemal complex holds the homologous chromosomes together like a zipper in a tetrad.

Term
the formation of what leads to crossing over between homologous chromsomes?
Definition

synaptonemal complex

 

the cross over part is called the chiasma and the crossed over alleles are called the recombinant chromatids

Term
what is the result of crossing over?
Definition
recombinant chromosomes with new combinations of linked genes
Term
name the four sources of genetic variability in sexual life cycles
Definition
mutation, independant assortment, crossing over, random fertilisation of ova by sperm
Term

what does this figure signify?

223 8,388,608

Definition

the number of possible combinations of paternal/maternal chromosome types

 

combinations in offspring is 246 and crossing over adds even more variation

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