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Benzodiazepines
What ATI considers "everything" about...
11
Pharmacology
Undergraduate 4
03/22/2014

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Cards

Term
Therapeutic uses of Benzodiazepines:
Definition

* promote sleep

* ↓ anxiety

* treat epilepsy

*relax muscle spasms

*moderate sedation

Term
Suffixes
Definition

-pam

-lam

Term
Expected Pharacological Action
Definition

* ↑ inhibitory effects of GABA

*cause sedation (which helps promote sleep)

Term
Side and Adverse Effects
Definition

*drowsiness

*dizziness

*confusion

*anxiety

*tolerance (over weeks)

*withdrawal (requires taper)

*can have paradoxical effects in older adults

Term
Intervntions during use:
Definition

*oversee nighttime ambulation, esp. older adults

*watch for toxicity

*monitor for paradoxical reactions, esp. older adults

*monitor for tolerance

*taper to avoid withdrawal

Term
Benzo Toxicity S/S
Definition

*weakness

*slurred speech

*ataxia

*uncoordinated muscle movements

*respiratory depression

Term
Administrations
Definition
*PO 30 minutes before bedtime
Term
Pt Instructions
Definition

*30 minutes before bed, ensure 8 hours for sleep

*do not take alcohol or other CNS depressants

*notify provider of paradoxical reactions

Term
Contraindications
Definition

*pregnancy

*glaucoma

*children

Term
Precautions
Definition

*renal or hepatic impairment

*SIHI

*alcohol

*neuromuscular disorders

*chronic respiratory disorders

*sleep apnea

Term
Interactions
Definition

*CNS depressants (alcohol, opioids, etc)

*kava kava and valerian ( ↑ sedation)

*Cimetidine (↑ benzo level)

*smoking (↓ benzo effects)

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