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Brainstem Motor Nerve Systems
75
Medical
Graduate
03/14/2011

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Term
do the corticonuclear tract and corticospinal tract run together?
Definition
yes, they course adjacently
Term
where does the corticonuclear tract come from in the cortex? and where is it going?
Definition
lower lateral gyrus
interneurons or nuclei in
Term
genu of internal capsule
Definition
carries corticonuclear fibers
Term
where do the corticonuclear tracts course in the midbrain?
Definition
medial end of the middle 3/5 of crus cerebri
Term
where is GSE in pons and medulla?
Definition
medial
Term
where is the SVE in brainstem?
Definition
lateral part of motor region, adjacent to sulcus terminalis
Term
what do striated mm. supplied by cranial nn develop from?
Definition
segmental embryonic structure
Term
cranial original segments are called
Definition
somitomeres (not morphologically obvious)
Term
extraocular, tongue and SCM and trapezius are
Definition
Somatic
Term
branchiomeric
Definition
striated muscles from pharyngeal arches
fibers to are SVE
masticatory
facial
palatal-pharyngeal-laryngeal mm.
Term
what are the two classes of striated muscle innervated by cranial nerves?
Definition
GSE and SVE
Term
occulomotor
Definition
rostral midbrain, next to midline
GSE to extraocular mm. course ventrally to interpeduncular fossa
Term
E-W nucleus
Definition
lateral to III nuclei
GVE fibers to sphincter pupillae and ciliary muscle
Term
how do fibers to superior rectus run?
Definition
they decussate to opposite
Term
what fibers innervate the levator palpebrae superioris?
Definition
fibers from a median subnucleus that innervates these muscle bilaterally
Term
arteries that supply edinger-westphal and occulomotor nuclei
Definition
paramedian branches of the basilar artery
Term
III LMN lesion
Definition
ipsilateral ptosis, abduction and depression (unopposed LR and SO)
contralateral effects --> elevation weakness, loss of convergence (no MR), atrophy
Term
EW lesion
Definition
dilated pupil- mydriasis; focusing weakness
Term
III and EW lesion
Definition
abducted eye + large pupil help localize lesion to rostromedial midbrain
a blown pupil can indicate central OR peripheral 3rd lesion, EW and motor lesions often occur together due to proximity
Term
III UMN lesion
Definition
similar to LMN but no atrophy and no parasympathetic loss
Term
where is trochlear nucleus located in the midbrain?
Definition
right above the MLF in caudal midbrain adjacent to the midline, GSE fibers to superior oblique cross dorsally
Term
superior oblique muscle does what?
Definition
abducts, depresses and intorts the eye; paramedian branches of the basilar artery supply trochlear nucleus
Term
IV LMN lesion
Definition
contralateral SO muscle paralysis (affected eye goes up and in)causes diploplia, may compensate with head tilted (toward lesion) and chin tucked, normal eye intorted to even eye levels
Term
trigeminal motor nucleus
Definition
lies in tegmental rostral pons between SCP and ML, medial to chief sensory nucleus
Term
where do trigeminal motor nucleus fibers exit brainstem?
Definition
exit through MCP at upper lateral pons
Term
trigeminal motor nucleus blood supply
Definition
SCA, AICA, and long circumfrential arteries of the basilar artery; lateral pontine symdrome includes masseter palsy
Term
V-LMN lesion
Definition
atrophy of masticatory muscles
protrudes jaw toward lesion side, ipsilateral hyperacusia
masseter and temporalis atrophy
Term
VI function
Definition
ipsilateral lateral rectus eye abduction and coordination of conjugate horizontal gaze
Term
caudal pons in 4th vetricle floor
Definition
abducens nucleus
GSE axons course ventrally to exit at pontomedullary junction, pass through pyramids
Term
MLF horizontal gaze center
Definition
coordinate III and VI; III, VI and IV are coordinated together from BA 8 of the cortex
Term
how is it ensure that the lateral rectus and medial rectus contract at the same time so we can look to the right?
Definition
Paramedian pontine reticular formation
frontal eye cortex travels to PPRF and those neurons send axons to LMN of ipsilateral abducens and contralateral III nucleus for medial rectus
Term
MLF includes fibers of horizontal gaze center
Definition
2 way association bundle that allows 3,4,6 nuclei to be coordinated
Term
VI LMN lesion of intrabulbar fascicles
Definition
ipsilateral lateral rectus paralysis
Term
VI LMN nucleus lesion
Definition
neither eye can look in the ipsilateral direction because interneuron that innervates contralateral MR
Term
VII motor nucleus
Definition
SVE fibers course dorsomedially, loop around VI nucleus and descend ventrolaterally to emerge at the cerebellopontine angle (this loop is called the internal genu; innervates stylohyoid, stapedius,posterior digastric and facial muscles
Term
GVE of Facial nucleus; strange route of fibers forms bump in floor of 4th ventricle, facial colliculus
Definition
submandibular ganglion from superior salivatory nucleus
Term
superior salivatory nucleus
Definition
interpontine tegmentum, dorsoalteral to VII motor nucleus, fibers run with VII motor fibers, lesion to this nucleus results dry eye/mouth
Term
VII LMN lesion
Definition
complete hemifacial paresis/paralysis, can't close eye, smoothing out of forehead, eyebrow droop, drooling, difficult to chew
Term
UMN VII input to upper face
Definition
bilateral; the significance of this is that UMN lesion on one side will have little to no effect on facial muscles since there is compensatory innervation
Term
VII UMN input to lower face
Definition
crossed; there will be contralateral lower face paralysis
Term
VII UMN lesion of upper face manifests how?
Definition
paresis, mild paralysis, not noticeable
Term
VII UMN lesion of lower face
Definition
contralateral spastic paralysis of lower face
Term
IX SVE fibers
Definition
located in ventrolateral medulla; nucleus ambiguus --> stylopharyngeus m.; lesion leads to mild dysphagia
Term
X
Definition
contains SVE fibers and GVE fibers
SVE fibers from nucleus ambiguus
GVE from dorsal motor nucleus
Term
SVE X fibers supply
Definition
soft palate, pharynx and larynx; LMN lesion includes flattened palate, loss of gag reflex on one side, uvula deviation away from lesion, (levator palatini) loss of swallowing, hoarseness
Term
where is nucleus ambiguus located?
Definition
medial to spinal trigeminal nucleus in medulla, shared with IX
Term
X LMN lesion in vocal cords
Definition
ipsilateral vocal fold in neutral position, abd/adductor paralysed; vocal fold can not get to midline to vocalize and can not fully abduct to breathe
Term
ipsilateral paralysis of the soft palate
Definition
X LMN lesion in nucleus ambiguus
Term
UMN lesion contralateral; always spastic paralysis
Definition
mainly crossed so uvula deviates towards side of lesion (would we still have swallowing reflexes and gag reflex?
Term
X dorsal motor nucleus
Definition
supplies GVE parasympathetic fibers to thoracic and abdominal effectors; is located lateral to hhypoglossal nucleus in floor of 4th ventricle
Term
lesion of dorsal motor nucleus: X
Definition
loss of heart rate lowering fibers causing relative tachycardia
Term
PICA infarct
Definition
knock out dorsal motor nucleus and nucleus ambiguus at the same time
Term
lateral medullary (Wallenburg)
Definition
PICA infarct; dysphagia, hoarseness, loss of gag reflex and thorocolmbnar parasympathetic regulation
Term
Hypoglossal nucleus
Definition
located midline in caudal medulla; fibers run lateral to ML and come out ventral to olivary nucleus
Term
intrinsic toungue mm. -- stylo, hylo and genio
Definition
XII; paramedian branches of anterior spinal artery will supply this nucleus
Term
XII LMN innervation
Definition
is ipsilateral
flaccid paralysis, atrophy, protrusion toward side of lesion
Term
UMN XII lesion***
Definition
protrusion of tongue away from lesion; no atrophy
Term
General Visceral Efferents of the head
Definition
preganglionic parasympathetic fibers that innervate smooth muscles and glands
Term
SVE fibers in the head innervate what?
Definition
branchiomotor muscles which are striated muscles that are derived fromthe branchial arch structures
Term
cranial nerves carry GSE or SVE but not both, which nerves carry which kind of fibers? Some fibers all carry GVE
Definition
III -- GSE and GVE
IV --GSE
V--SVE
VI -- GSE
VII -- SVE and GVE
IX -- SVE and GVE
X-- SVE and GVE
XII -- GSE
Term
In the pontine basis where is the CNT in relation to the CST?
what is the relation in the medulla to the pyramids?
Definition
ventral
dorsal
Term
how many motor nuclei does cranial III have?
Definition
III :)
Term
describe the location and function of the subnucleus for LPS
Definition
subnucleus for levator palpebrae is unpaired (in the midline) and serves both sides
Term
describe the path of the subnuclear fibers for the superior rectus muscle
Definition
subnuclear fibers for superior rectus cross and pass through the opposite subnuc.
Term
describe the path of cranial n III intrabulbar fibers
Definition
intrabulbar axons course ventrally (actually passing through the red nucleus !) to exit into the
interpeduncular fossa
Term
UMN input to trochlear nucleus is contralateral or ipsilateral?
Definition
It is ipsilateral and lUMN lesion will be the same as LMN lesion except w/o atrophy
Term
what muscles does the trigeminal motor nucleus supply?
Definition
ipsilateral tensor tympani and levator palatini, masticatoty muscles and mylohyoid; efferent limb of jaw jerk reflex
Term
how does an UMN V lesion manifest?
UMN input to V is bilateral
Definition
CNT lesion above the trigeminal doesn’t significantly affect masticatory function, but the jaw
jerk may be exaggerated
Term
VI intrabulbar fiber lesion
Definition
ipsilateral eye is adducted
Term
VI nucleus lesion
Definition
eye adduction and conjugate gaze palsy (can not look to the direction of lesion with opposite eye)
Term
UMN lesions always cause
Definition
spastic paralysis
Term
describe GVE innervation to parotid gland
Definition
IX fibers that split after jugular foramen --> GVE to parotid gland come from inferior salivary nucleus
Term
what is the exception to bilateral supranuclear control of vagal motor responses?
Definition
the uvular muscle, which is crossed; UMN X lesion leads to spaticity and uvula pointing towards lesion
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