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Bacteriology Gram Positive
BacT Test 2
211
Veterinary Medicine
Graduate
10/23/2011

Additional Veterinary Medicine Flashcards

 


 

Cards

Term
Streptococcus
Definition

pyogenic

catalase neg

hemolysis

M Protein

Ig binding proteins

Streptolysin

Term
Streptococcus form
Definition
cocci in chains
Term
Lancerfields serogrouping
Definition
beta, alpha, and gamma hemolysis
Term
Streptococci cell associated virulence factors
Definition

Capsule

Peptidoglycan

techoic acid

M Protein

Ig binding protein

Term
Streptococci extracellular virulence factors
Definition

DNA ase

Hyaluronidase

C5 peptidase

NADase

toxins: Streptolysin O & S, superantigens

Term
Streptococcus habitat
Definition
Mucous membranes
Term
Streptococcu related genera
Definition
enterococcus, peptidococcus, abiotrophia, granulicatella
Term
S. equi
Definition
Equine strangles
Term
S. equi id
Definition

Beta hemolytic group C strep

mucoid because of hyaluronic acd capsule

Term
S. equi must be distinguished from
Definition
S. zooepidemicus & S. equisimilis
Term
S. equi cllular virulence
Definition

Hyaluronic acid capsule

M protein

IgG FC binding proetins

Term
s. equi extracellular virulence propertes
Definition

streptokinase

hyaluronidase

Streptolysin S

DNAase

SPEs

Term
Beta strep is susceptible to...
Definition
more common drugs, don't have to susceptibility testing
Term
S. equi animals of high risk
Definition
foals 4m-2yrs of age, losing paternal antibodies
Term
S. eqiu transmission
Definition
inhaled or ingested
Term
S. equi clinical signs appear
Definition
3-14days after exposure
Term
S. equi 1st sign
Definition
fever
Term
S. equi is often carried
Definition
gutteral pouch
Term
S. equi lymphnode abcessation appears
Definition
within 2 weeks of initial signs
Term
S. equi complicaions
Definition
bastad strangles or purpura hemorrhagica
Term
S. eqi nasal sedding begins how many days after exposure ?(remember this is with or without evidence of nasal discharge)
Definition
4-7 days
Term
S. equi convalescent shedders can shed for
Definition
up to 6wks
Term
S. equi long term shedders can shed for
Definition
5-7 months
Term
S. equi recorvery
Definition
usually spontaneous
Term
S. equi treatment
Definition
symptomatic
Term
S. equi control
Definition
quarentine infected animals and hygeine
Term
S. equi vaccine
Definition
killd & live using M protein, pregnate mares and foals
Term
S. equi diagnosis
Definition
culture, 3 negs at weekly intervals; test GP >30 days after recovery for long term carriers
Term
Clostridium
Definition

Large endosporeforming rods

mostly hemolytic

highly fermentaive & proteolytic

Term
Clostridium exotoxins
Definition

lectinase. alpha- toxin

DNAase

Term
Clostridium habitat
Definition

Soil

intestins of animals

Term
Clostridium neurotoxic diseases
Definition
tetanus & botullism
Term
enteric clostridium
Definition
C. perfringens
Term
Non-enteric Clostridium
Definition

Blackleg

Gas gangrene

Malignate edema

Term
C. Sordelli
Definition
associated with enteric and non-enteric disease of livestock
Term
C. tetani
Definition

anaeobic

terminal endospore - tennis racquet

Term
C. tetani habitat
Definition

feces & soil

contaminated wounds

Term
C. tetani neurotoxin
Definition
tetanospasmin
Term
Tetanospasim
Definition
Only antigenic type for C. tetani
Term
C. tetani neurotoxin causes ascending toxemia by entering though the
Definition
nervous system
Term
C. tetani causes descending by entering through
Definition
circulatory system to the CNS
Term
C. tetani most susceptible
Definition
horse, man, guinnea pig
Term
C. tetani least suceptible
Definition
birds
Term
C. tetani early sign
Definition
3ed eyelid prolapse
Term
C. tetani signs occur
Definition
3-18 days after injury
Term
C. tetani treatment
Definition

antitoxin

antibiotic

clean wound

suportive care

Term
C. tetani control
Definition

vaccinate

prompt wound cleaning

Term
intxication rather than infection is caused by
Definition
C. botulism
Term
C. Botulism neurotoxins
Definition
8 (A-G)
Term
Shaker foal syndrome
Definition
caused by C. Botulism
Term
C. botulism signs
Definition

double vision

difficulty standing or swallowing

Term
C. botulism often found
Definition
high protein canned foods
Term
affecte mostly by C. botulism
Definition

mink farms

artic foxes

water fowel

Term
C. botulism diagnostic
Definition
Mouse neutralization test is the gold standard
Term
C. botulism control
Definition

immunize high risk animals

avoid feedin suspected food types

Term
Common cause of enterocolitis
Definition
C. perfrngens & C. difficle
Term
rarely sporulates in vitro
Definition
C. perfringens
Term
C. perfringens double zine hemolysis due to
Definition
alpha toxin (lectinase)
Term
C. perfrigens major toxins
Definition
4 (A-E)
Term
Alpha toxin
Definition
lectinase
Term
Beta toxin
Definition
pore forming, Made by type C
Term
Type B
Definition
Not found in US
Term
Types C & D
Definition
usually pesent in cattle
Term
Type C
Definition
trypsin inactivated, infants more susceptible
Term
Type D
Definition
Makes epsilon
Term
Turned on by trypsin activation
Definition
Type D
Term
Causes pulpy kidney disease
Definition
Epsilon, C. perfringens
Term
C. perfringens additional toxins
Definition

CPE - only during sporulation

Beta-2 toxin

Term
C. perfringen mouse neutralization test
Definition
look for toxins in GI content
Term
C. perfringens treatment
Definition
hyperimmune syrum if given early
Term
Antibiotic treatment
Definition
Not recommended for C. perfringens
Term
C. perfringens control
Definition

avoid sudden diet changes

routine immunization

Term
Overeatig disease
Definition
C. perfringens, uually in young feed animals
Term
Often confuse with streptococcus
Definition
Listeria
Term
Listeria
Definition

small gram positive rods

non-sporeforming

catalase positive

wide temperatue growth range

mobile at certain temperatures

Term
Listeria growth range
Definition

likes it cold

doesn't like pH below 5.5

motile at <25C

Term
Listeria serotyping
Definition

Cell wall O antigen

Flagellar H antigen

Term
Most frequent and pathogenic
Definition
Listeria monocytogens
Term
occasional - associated with sheep abortions
Definition
L. ivanovii
Term
rare, reported CNS in ruminants
Definition
L. innocua
Term
Listeria habitat
Definition
soil, water, and sillage
Term
Listeria virulence
Definition

internalins

listeriolysin

phospholipases

Act A

Term
High risk for Listeria
Definition

neonates

pregnate females

elevated iron

elderly

stress

Term
Listeria contraction
Definition
ingestion or occular instillation
Term
Listeria disease
Definition

encephalitis

speticemia

abortion

ocular forms

Term
Choriorinitis
Definition
hematogenous
Term
keratoconjunctivitis
Definition
exogenous
Term
Bovine encephalitis listeriosis
Definition
Bovine CNS disease, head tilt and circling
Term
Bovine encephalitis listeriosis diagnosis
Definition
migroscopic detection, gram stain
Term
Bovine encephalitis listeriosis treatment
Definition

antibiotic if given early

cotricosteroids to reduce inflammation

Term
Has no vaccine
Definition
Listeria (Bovine encephalitis listeriosis)
Term
Listeria control
Definition

Be aware of predisposing factors

pH below 5.5

avoid high levels of exposure

Term
Erysiplothrix rheusiopathiae
Definition

small rods

bottle-brush appearance

grows over a wide temperature range

salt tollerant

H2S positive

Term
Erysiplothrix rheusiopathiae virulent form
Definition
short rod, smooth colonies
Term
Erysiplothrix rheusiopathiae avirulent form
Definition
filamentous rough colony
Term
Erysiplothrix rheusiopathiae serotyping
Definition
cel wall antigens, >23 types
Term
Good to know if asking "does the herd next door have the same bug as my herd does?"
Definition
serotype
Term

Most frequent

commin in pigs and birds

Definition
Erysiplothrix rheusiopathiae
Term

less common

associated with disease in dogs

Definition
erysiplothrix tonsillarum
Term
Erysiplothrix rheusiopathiae habitat
Definition

wide spread

tonsils or feces of carriers

fresh or salt water

Term
Erysiplothrix rheusiopathiae virulence factors
Definition

capsule-like antiphagocytic surface material

adhesions

neuraminadase

Term
Hyaline thrombi
Definition
often seen in Erysiplothrix rheusiopathiae
Term
Erysiplothrix rheusiopathiae dseases
Definition

fish handler's disease

abortion

dismond skin

arthritis

 

Term
Erysiplothrix rheusiopathiae diagnosis
Definition
culture
Term
Erysiplothrix rheusiopathiae treatment
Definition
antibiotics of acute infections
Term
Erysiplothrix rheusiopathiae control
Definition

good hygiene

cull

 vx

Term
Erysiplothrix rheusiopathiae vx
Definition

pigs and turkeys

live attenuated + bactrin

 

Term
Erysiplothrix rheusiopathiae capsule-like surfce proteins enable it to have what vs Listeria
Definition
vaccine
Term
Actinomyces
Definition

non-acid fast

filamentous rod branching

facultative & anaerobic

dry, off-white "molar tooth-like" colonies

 

Term
Actinomyces virulence
Definition
not well defined, some adhesions
Term
Actinomyces habitat
Definition
mucoas of oropharynix
Term
Actinomyces disease
Definition

chronic, progressive, pyogranuloatous

can lyse bone

Term
common disease in field dogs
Definition
Actinomyces
Term
lumpy jaw
Definition
Actinomyces bovis
Term
Actinomyces bovis
Definition
"cheese-like" granulomas that have ray like clubs
Term
Actinomyces diagnosis
Definition

culture

examin granules

Term
Actinomyces treatment
Definition

long term 3-12 months with penicillin

remove foreign body

Term
Actinomyces control
Definition

avoid injury

remove foreign bodies

Term
Dermatophilus
Definition

tram track branching

coccoid zoospores

aerobic

catalase positive

hemolytic carotenoid pigment

Term
Dermatophilus habitat
Definition
skin of infected animals
Term
Dermatophilus diseases
Definition

Rain scald

strawberry footrot

reptiles can get it

Term

Dermatophilus virulence

 

Definition

chemotaxis of zoospores

survives in crusts

Term
Dermatophilus diagnosis
Definition
micorscopic - very unique
Term
Dermatophilus treatment
Definition

usually resolve on their own

sympamatic antibiotic treatment

Term
Dermatophilus control
Definition

dry shelter

remove ticks

brush removal

Term
Mycobacterium
Definition

acid fast

obligate aerobe

rods

Term
Lowenstein Jensen media
Definition
fatty acid enriche media required for growth of pathogenic Mycobacterium species,no agar
Term
shortest mycolic acid chain
Definition
corynebacterium
Term
longest myclic acid chain
Definition
Mycobacterium
Term
Mycobacterium rapid growing is longer/shorter than Mycobacterium slow gowing
Definition
shorter
Term
Mycobacterium immonumodulating activities
Definition

lipoarabinomannan

lipoarabinogalactan

wax D

Term
Mycobacterium prevents phagocytic killing due to
Definition

trehalose dimycolate

phenoilc glycolipid

sulphate glycolipids

Term
cord factor
Definition
trehalose dimycolate
Term
phenolic glycolipid
Definition
scavenger of O2 radicals
Term
sulphated glycolipids
Definition
prevent lysosome fusion
Term
photochromogens
Definition
pigmented in the prsence of light
Term
scotochromogens
Definition
pigmented in the absence of light
Term
Mycobacterium rapid growers
Definition
<7 days
Term
Mycobacterium slow growers
Definition
2-10 weeks
Term
Mycobacterium habitat
Definition

obligate pathogens

some are water/soil saprophytes

Term
Leprosy
Definition
Mycobacterium affectes rodents and some cats
Term
Mycobacterium diseases
Definition

M. Bovis

M. Avium

M. tuberculosis

Non-tuberculosis

Leprosy

Term
Mycobacterium bovis
Definition

slow growing 20-24hrs

indstinguishable from M. tuberculosis

 

Term
Mycobacterium bovis compared to M. tuberculosis is
Definition
less resistant and harder to isolate
Term
Mycobacterium bovis signs
Definition
not seen until advaced stages (usually seen at slaughter)
Term

broadset of all host range

mainly bovine

cervids

 

Definition
Mycobacterium bovis
Term
Mycobacterium bovis transmission
Definition
Aerosol & milk, any body site
Term
Mycobacterium bovis first sign
Definition
enlarged regional lymphnodes
Term
what causes disease in Mycobacterium bovis
Definition
cell-mediated immunity (Tubercle)
Term
Mycobacterium bovis treatment
Definition

not practicle in animals

in humans use combination, prolonged drug treatment

Term
Mycobacterium bovis control
Definition

no method for elimination

in low incidences: slaughter, plant survalence, traceback

emphasis on erradication

Term
Mycobacterium bovis principle risks
Definition
shared pastures, endemic in possum, badger, and water buffalo
Term
Mycobacterium bovis vaccine
Definition

no vx in cattle

Vx in humans - live attenuated BCG

Term
BCG & DNA
Definition
best bet for vx for Mycobacterium bovis
Term
Tuberculin hypersensitivity skin test first cecked where?
Definition
caudal tail fold
Term
check tuberculin skin test after 72hrs for?
Definition
skin thickness
Term
skin thickness in Mycobacterium bovis test indicates what?
Definition
macrophage accumulation
Term
Second test for Mycobacterium bovis gives doses of what?
Definition
M. Bovis PPD and M. avium PPD
Term
used in zoo and wildlife species for Mycobacterium bovis
Definition
lymphocyte prliferation assays
Term

serology used for elephants to detect

Mycobacterium bovis along with trunk washings

Definition
Multiantigen print immunoassay (MAPIA)
Term
Mycobacterim avium
Definition

4 types of subspeces

Non-tuberculosis

slow-growing

non-chromogen

Term
Mycobacterim avium habitat
Definition
soil and even found in municiple tap water
Term
affects birds
Definition
Mycobacterim avium
Term
causes bottle jaw
Definition
M. avium subsp paratuberculosis
Term
M. avium subsp paratuberculosis
Definition
johne's disease
Term
M. avium subsp paratuberculosis signs
Definition

chronic diarrhea

wasting

thicened ileal mucosa

no fever

lots of granulomatous masses

Term
susceptible to M. avium subsp paratuberculosis
Definition
young animals right after birth
Term
M. avium subsp paratuberculosis vaccine
Definition

used in situational problmes

can cause reaction

live vaccine

Term
M. avium subsp paratuberculosis transimission
Definition
fecal-oral
Term
M. avium subsp paratuberculosis growth time
Definition
10 weeks one of the slowest
Term
postive confirmed for M. avium subsp paratuberculosis by
Definition
acid-fast stain & PCR for IS900
Term
M. avium subsp paratuberculosis negative confirmed by
Definition
acid-fast stain
Term
fecal culture for M. avium subsp paratuberculosis used for
Definition
herd initial analysis
Term
Johnin hypersensitivity skin test
Definition
poor test, not used widely
Term
M. avium subsp paratuberculosis serology
Definition
for confirming diagnosis and monitoring herd
Term
T/F Antimicrobial treatment is recommented for M. avium subsp paratuberculosis
Definition
F
Term
M. avium subsp paratuberculosis control
Definition

focus is on reduction not erradication.

test animals, cull clinical cases quickly, isolate/saughter infected animals

Term

Can take up to how many years to achieve a

M. avium subsp paratuberculosis negative herd?

Definition
10
Term
Corynforms
Definition

of order Actinomycetes

pleomorphic rods

usually not acid fast

Term
Corynebacterium
Definition

catalase positive

diptheria in humans

lipophilic vs non-lipophilic species

Term
Corynebacterium lipophilic virulence fators
Definition

corynemycolic acids

phospholipase D

Term
Corynebacterium non-lipophilic virulence
Definition

fimbrae

diptheria toxin

urease

Term
dull-dry clonies
Definition
lipophilic Corynebacterium
Term
creamy white or yellow colonies
Definition
non-lipophilic Corynebacterium
Term
Corynebacterium habitat
Definition
skin and mucous membranes, most are not pathogenic
Term
Corynebacterium Pseudotuberculosis
Definition

lipophilic

dry "cheese-like lesions"

antibiotic tx

variant is pidgeion fever in horses

Term
Corynebacterium renale
Definition
urinary tract disease, appears yellow
Term
Contageous bovine pyelonephritis
Definition

C. renale (and others)

disease of adult cows

trauma to bladder

 

Term
Contageous bovine pyelonephritis signs
Definition

temp increase

painful urination

decreased milk production

multifocal abcesses in renal cortex, medulla, pelvis

enlarged regional lymphnodes

Term
T/F Lipophilc, unlike non-lipophilic, Corynebacterium is ofter resistant to multiple antibiotics
Definition
T
Term
Corynebacterium control
Definition

treat and isolate infected animals

cull

immunization

Term
Corynebacterium vaccine includes
Definition
diptheria toxoid, PLD toxoid
Term
Foal pneumonia
Definition
Rhodococcus equi
Term
Rhodococcus equi
Definition

rods or cocci

wealky acid fast

aerobic

catalase positive

urease & nitrate positive

 

Term
cholesterol oxidase
Definition
equi factor - enhances emolysis of wealky hemolytic organisms - CAMP-like reaction
Term
Rhodococcus equi presents growth at
Definition
48-72hrs
Term
Rhodococcus equi Habitat
Definition

soil, virulence is maintained mostly in horses

opportunistic

Term
Rhodococcus equi most suceptible
Definition
foals 1-3 months of age
Term
Rhodococcus equi transmission
Definition
inhalation, ingestion, across mucus membrane
Term
Is Rhodococcus equi associated with good hygiene practices
Definition
no
Term
Rhodococcus equi diagnosis
Definition
difficult to obtain becasue need respiratory sample and anima is often already in respiratory distress
Term
Rhodococcus equi early screening includes checking
Definition

elevated plasma fibrinogen protein in blood

rectal temp 2x day

physical exam 2x wk

CBC for increased WBCs

Term
Rhodococcus equi treatment
Definition

 may be prolonged 7 days - >3 wks

expensive

clarithromyci or azithromycin with rifampin

Term
Rhodococcus equi control
Definition

hyperimmune serum given early

 vaccinatio of mares does NOT work

early detection, treatment, and environmental management needed

Term
Nocardia
Definition

fiberous branching

coccoid aerial fragments

partially acid-fast

aerobic

catalase positive

sabouraud-dextrose agar

caretnoid pigment

Term
Nocardia virulece
Definition

mostly unknown

nocardiomycolic acid

facultative intracellular survival

Term
Nocardia habitat
Definition
soil
Term
Nocardia disease
Definition

oportunistic

pyogranulomatous infections

mastitis

Term
Nocardia treatment
Definition
susceptible to antibiotics but MUST use multiple rug treatment
Term
Nocardia control
Definition

difficult

maintain immunocompetency

is sporadic

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