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Bacterial Genetics II
i love bacteria bacteria bacteria bacteria loves me.
20
Medical
Undergraduate 2
03/03/2009

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Term
Name the three mechanisms that bacteria use to adapt to changing environments:
Definition
1.) mutation
2.) gene transfer
3.) regulation of gene expression
Term
what are MUTATIONS?
Definition
stable heritable changes in the base sequence of DNA
Term
how can mutations occur?
Definition
1.) base substitutions
2.) removal or addition of nucleotides
3.) transposable elements
Term
what is the most common type of spontaneous mutation?
Definition
base substitution! results from mistakes during DNA synthesis. Incorrect base is incorporated into DNA :(
Term
What is the name for the mutatation when one base pair is changed?
Definition
A POINT MUTATION is when one base pair is changed.
Term
a mutation occuring from amino acid substitution is called a...
Definition
MISSENSE MUTATION
-->this is dumb, but (think: double letter "s": mi-SS-ense; double letter "a" A.A.= amino acid). it's a stretch, I know.
Term
what is the name of a mutation that changes an amino acid codon to a stop codon?
Definition
a NONSENSE mutation. NON=no longer shall this continue, we must stop. non-progress. non-pass go. do non- collect 500 dollars.
Term
what happens in a FRAMESHIFT mutation?
Definition
affects all amino acids downstream from an addition or deletion.
Term
mutations frequently cause premature.........
Definition
STOP CODONS
Term
what are TRANSPOSABLE ELEMENTS?
Definition
Special segments of DNA that move spontaneously from gene to gene.
Term
what do TRANSPOSONS do?
Definition
disrupt proper function of gene. Gene or gene product generally non functional.
Term
Mutations are essential for understanding genetics. Mutations can be INTENTIONALLY produced to demonstrate __________ of particular gene or set of genes.
Definition
FUNCTION
Term
What are three ways mutations can be induced?
Definition
1.) chemical mutagens
2.) transposition
3.) radiaiton
Term
what's the deal with nitrous acid?
Definition
converts amino group to a keto group (cytosine to uracil)
Term
What are three signs that Travis is sleeping?
Definition
1.) bobble-head like characterists, with intermittent periods of extreme stillness
2.) purring slightly while hand absent-mindedly caresses LA TIGRE
3.) mouth gaping open so wide one might be tempted to toss in a shoe-like projectile or three fists or a large rabbit.
Term
What is the largest group of mutagens?
Definition
ALKYLATING AGENTS
Term
Name a common alkylating agent preeze.
Definition
Nitrosoguanine.
Term
What is the name for a common procedure used to induce mutation in laboratories?
Definition
TRANSPOSITION
Term
A gene that recieves transposon will undergo a knockout mutation, known as a...
Definition
insertion mutation
Term
What are the two types of radiation and what do they cause?
Definition
UV light- causes covalent bonding between adjacent thymine bases.
X-rays-causes breaks and alterations in DNA
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