Term
What percentage of AD will develop asthma?
AD onset is usually before five years of age in what percentage of patients? |
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Definition
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Term
| What diagnosis is considered in an adult with new onset dermatitis and no history of childhood eczema, asthma or AR? |
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Definition
| cutaneous T-cell lymphoma (CTCL)- consider skin biopsy |
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Term
What chemokines are found in AD?
What cytokines are associated with acute AD?
chronic AD? |
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Definition
CCL27, TARC
IL-4, IL-13
IL-5, IL-12, IFN-gamma |
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Term
| What is associated with increased colonization with S. aureus in AD? |
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Definition
| decreased antimicrobial peptides, H-beta-defensins and human cathelicidin |
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Term
| What are the features of Netherton syndrome? |
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Definition
| scaly dermatitis with short, spiky, brittle hair or "bamboo hair" |
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Term
| What are the features of lichen simplex chronicus? |
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Definition
| On neck and fold behind ears, accentuation of surface marking (resembles tree bark), response to repeated rubbing/scratching |
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Term
| What are the features of acrodermatitis enteropathica? |
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Definition
| eczema that does not respond to steroids, periorificial rash, necrotic area around nose (due to zinc deficiency) |
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Term
What are the features of pyridoxine and niacin deficiency?
Multiple carboxylase deficiency?
Phenylketonuria? |
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Definition
seizures, irritability, cheilitis
skin rash, alopecia, lethargy
pale pigmentations, blue eyes, scleroderma |
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Term
| What are the features of Letterer-Siwe disease? |
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Definition
| anemia, thrombocytopenia, LAD, histiocytic infiltration of the liver/spleen/lymph nodes |
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