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AP Biology Chapter 13
Simon Kenton
33
Biology
12th Grade
02/23/2012

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Term
Hershey and Chase
Definition
Discovered that DNA is the genetic material
Term
Rosalind Franklin
Definition
Took X-ray pictures of DNA
Term
Watson and Crick
Definition

Discovered the structure of DNA

The 3 major features of DNA...

1.  DNA is a double helix

2.  4 Nitrogen Bases

3.  Strands are antiparallel

 
Term
Antiparallel
Definition
DNA strands run in opposite directions
Term
What is DNA made of
Definition

Deoxyribose

Phosphate

Nitrogen Bases

Term
What is the backbone of DNA?
Definition
Deoxyribose and Phosphate
Term
What are the 4 nitrogen bases in DNA?
Definition

1.  Adenine

2.  Guanine

3.  Cytosine

4.  Thymine

Term
What joins the 2 strands of DNA together?
Definition
Hydrogen Bond
Term
DNA
Definition
deoxyribose nucleic acid
Term
Nucleotide
Definition
Made of deoxyribose, phosphate and nitrogen base
Term
Pyrimidines
Definition

Single Ring

Ex: Thymine and Cytosine

Remember the Y's

Term
Purines
Definition

Double Rings

Ex: Adenine and Guanine

Term
Chargaff's Rule
Definition

Amount of A = T

Amount of C = G

Term
Complementary Base Pairs
Definition

Adenine bonds with Thymine

Cytosine bonds with Guanine

Term
DNA is in the shape of a
Definition
double helix
Term
The 2 strands of DNA are
Definition

complementary

that means that A bonds with T and

C bonds with G

Term

All species are made of A, T, C and G.

The only difference between species is...

Definition
how many nitrogen bases and in what order.
Term
DNA Replication
Definition

Making a copy of DNA

Occurs during the S phase of the cell cycle

Term
Semiconservative Replication
Definition

After replication the 2 molecules of DNA will consist of an old strand and a new strand of DNA

Term
What is the enzyme that unwinds and unzips the DNA for replication?
Definition
DNA Helicase
Term
What is the enzyme that removes twists and knots that may form as the DNA is unziped?
Definition
Topoisomerase
Term
What is the enzyme that adds on the the DNA nucleotides?
Definition
DNA Polymerase
Term
DNA Polymerase moves from...
Definition
3' to 5'
Term
The new complement strand of DNA grows in the...
Definition
5' to 3' direction
Term

The strand of DNA that goes from 3' to 5' in the same direction as the replication fork is the _____ strand.

Definition
Leasing
Term
Leading Strand
Definition

Replication occurs fast as the DNA polymerase adds on nucleotides in the same direction it is unzipping. 

This strand runs 3' to 5'

Term
Lagging Strand
Definition

DNA polymerase moves away from the replication fork.

Is slower than the leading strand

DNA nucleotides are added in fragments

Term
The strand of DNA that goes from 5' to 3' and in the opposite direction of the replication fork is called the _____ strand
Definition
Lagging Strand
Term
Okazaki Segments
Definition

Short segemnts of DNA made on the lagging strand during replication

Term
DNA Ligase
Definition

Connects Okazaki segements to produce a single complementary strand of DNA

Term
Mismatch Repair
Definition

Special repair enzymes fix incorrectly paired nucleotides

Term
Nucleotide Excision Repair
Definition
Incorrectly placed nucleotides are excised (removed) by enzymes called nucleases.
Term
Telomeres
Definition

Short repetitive nucleotide sequences that do not contain genes at the ends of chromosomes

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