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Antibiotics 2
Pharm (III) exam 2
53
Pharmacology
Professional
04/15/2012

Additional Pharmacology Flashcards

 


 

Cards

Term
Use for Streptomycin
Definition
Gonorrhea
Term

Aminoglycoside

  • MOA
  • Resistance

 

Definition
  • Irreversibly binding 30S
  • Enzymes phosphorylate the drug
Term
Which class of antibiotics kill bacteria, even when it drops beow MIC due to production of mutant proteins?
Definition
Aminoglycosides
Term
Aminoglycosides end in
Definition
  • Mycin
  • Cin
Term

Aminoglycosides

  • Ideal target
Definition
  • Gram (-) aerobic in neutral
Term

Treat:

Enterococcal endocarditis

Definition
Aminoglycosides
Term

Treat:

Hospital acquired pneumonia

Definition
Aminoglycosides
Term

Sulfonamide

  • MOA
  • Resistance
Definition
  • Folic acid inhibition
  • Mutated Dihydropteroate synthetase
Term
Treat infection from a burn
Definition
Silver sulfadiazine
Term

TMP

  • MOA
  • Resistance
Definition
  • Inhibit Dihydrofolte reductase
  • Mutated Dihydrofolate reductase
Term
Treat chlamidia trachomitus
Definition

Sulfonamides

fluoroquinolones

Term
Which class of drugs cause Kernicterus so shouldnt be used for children under 2?
Definition
Sulfonamides
Term
Which class of drugs cause crystalurea?
Definition
Sulfonamides
Term
Drug used to treat Claustridium dificil associated pseudomembranous colitis
Definition
  • Metronidazole

 

Term
Which antibiotic can cause hyperkalemia
Definition
Trimethoprim
Term
Drug used as prophylaxis for UTI
Definition
  • SMZ/TMP
  • Cipro
  • Nitrofurantoin
Term
Treat prostatitus
Definition

SMZ/TMP

Fluoroquinolones

Term
Treat acute otitis media
Definition
SMZ/TMP
Term
Treat pneumocystis Jirobetsi pneumonia
Definition
  • SMZ/TMP
  • Steroids
Term
Fluoroquinolones end in
Definition
-floxacin
Term

WHich class of antibiotics is affected by antacids?

when should the drug be administered?

Definition

Fluoroquinolones

4 hours before or 2 hours after antacids

Term
Which of the fluoroquinolones is not renally cleared?
Definition
Moxifloxacin
Term

Fluoroquinolones

  • MOA
  • Resistance
Definition
  • Inhibit DNA gyrase & topoisomerase
  • mutant gyrase & topoisomerase
Term
Which group of antibiotics can cause damage to cartilage?
Definition
Fluoroquinolones
Term
Which group of antibiotics can cause a decreas in xanthine derivative excretion, so an increase in caffeine?
Definition
Fluoroquinolones
Term
Drugs for MRSA & Vancomycin resistant
Definition
  • Quinupristin/Dalfopristin
  • Linezolin
  • Daptomycin

"Keep your body in pristine condition by drawing a line in the sand and listening to dapt punk"

Term
Treat community acquired pneumonia
Definition
Fluoroquinolones
Term
Treat Resporatory track infections
Definition
Fluroquinolones (especially new)
Term
Treat skin, bone, and joint infections
Definition
Fluoroquinolones
Term
Which antibiotics can cause CNS side effects?
Definition
Fluoroquinolones
Term

Vancomycin

  • MOA
  • Resistance
Definition
  • Bind D-alanyl D-alanine, inhibit cell wall
  • change in cell wall enzymes
Term
Drug of choice for a gram + infection in a patient with allergy to penicillins and cephalosporins
Definition
Vancomycin
Term
Treat dairrhea caused by clostridium dificil
Definition
Vancomycin (PO)
Term
Red man syndrome
Definition
Vancomycin
Term

Clindamycin

  • MOA
  • Resistance
Definition
  • Bind 50s
  • Mutation in 50s
Term
Treat patients with a heart disease about to have a dental procedure
Definition

Clindamycin

take  before entering the dental clinic

Term

May cause pseudomembranous colitis from super infection by clostridium dificil

 

Definition

Clindamycin

Sulfonamides (per Azzedine)

Term

Nitrofurantoin

MOA

Definition
Reduced form damages bacterial DNA
Term
Use for nitrofurantoin
Definition
UTI
Term

Polymixin B

  • MOA
  • Resistance
Definition
  • Cationic detergent
  • inhibit from entering cell
Term
WHich antibiotic is advertised as reducing scars?
Definition
polymyxin B
Term

Metronidazole

  • MOA
Definition
  • Binds intracellular molecules

Metrosexuals like hugs, they bind to everyone

Term
Metronidazole ideal target
Definition
anaerobe or protozoans
Term
This antibiotic can cause disulfiran like reactions
Definition

Metronidazole

If you hang out with metrosexuals, you will drink girly drinks, hopefully you don't have disulfiran

Term

Bacitracin

  • MOA
Definition
Inhibit bacterial cell wall synthesis
Term

Quinuprestin/Dalfopristin

  • MOA
Definition
Bind 50s
Term

Linezolid

  • MOA
  • Resistance
Definition
  • Bind 50s
  • mutated 50s
Term
Which antibiotic has reversible MAO inhibitory effects?
Definition
  • Linezolid

Chaiman mao drew a line in the sand

Term

Daptomycin

  • MOA
Definition
  • Binds cell wall
Term
Bacteriostatic
Definition
  1. Sulfasalazines
  2. Clindamycin
Term
Prophylaxis for diarrhea
Definition
Cipro
Term
#1 choice for B. Fragilis
Definition

Metronidazole

it is so fragile that even a metronome can break it

Term
Used to treat ulcerative colitis
Definition

Sulfasalazine

(5-aminosalicyclate)

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