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Antibiotic Therapy Background
Some Common Terms
7
Pharmacology
Professional
08/18/2012

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Cards

Term
Describe Gram Positive
Definition
stain purple or bluish in color
Term
Describe gram negative
Definition
stain pink or reddish in color
Term
What is empirical treatment and what is the proper progression?
Definition

Empirical broad spectrum antibiotic treatment (that covers any possible organism) should be changed to directed antibiotic treatment as soon as possible (once gram stains are available, or preferably, specific cultures) in order to reduce the incidence of antibiotic resistance.

Term
Define Minimum Inhibitory Concentration (MIC)
Definition
Lowest drug concentration that prevents microbial growth
Term
Define Minimum bactericidal concentration (MIB)
Definition
lowest drug concentration that reduces bacterial density by 99.9%
Term
Define Synergy
Definition
effect of two or more agents produces a greater effect than each agent alone.
Term
What's the philosophy of peri-operative antibtiotic prophylaxis
Definition

(1)short course of antibiotic administered before there is clinical evidence of infection


(2)treatment usually begins 1/2 hour before surgical incision and continues for no longer than 24 hours


(3)first generation cephs are the drugs of choice for most procedures. In pcn-allergic patients, a suitable alternative is vancomycin

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