Term
| This drug blocks the M2 ion channel and is ONLY effective against influenza A |
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Definition
amantadine or rimantadine
(adamantane class) |
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Term
| These neuraminidase inhibitors work against both influenza A and B |
|
Definition
| zanamivir and osteltamivir (tamiflu) |
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Term
| This drug is a guanine analog that is used to treat herpes viruses, but not CMV |
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Definition
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Term
| This guanine analog is effective for killing CMV |
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Definition
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Term
This pyrophosphate analogue inhibits DNA polymerase and reverse transcriptase
has activity against: CMV, acyclovir resistant herpes virus, and minimal activity against HIV |
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Definition
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Term
| This nuceloside transcriptase inhibitor is a first-line anti-HIV medication |
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Definition
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Term
This drug interferes with DNA polymerase and reverse transcriptase
It has activity against HIV and Hepatitis B |
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Definition
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Term
| This neuraminidase inhibitor is only available as an intranasal spray |
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Definition
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Term
| This drug is licensed only for severe respiratory syncytial virus |
|
Definition
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|
Term
| These guanine analogs are used for herpes zoster and recurrent genital herpes |
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Definition
| Famciclovir and valacyclovir |
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|
Term
This drug is the L-valyl ester of gangciclovir and has much better bioavailability
It is used for VZV, HSV, CMV, EBV |
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Definition
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Term
| This deoxyguanosine nucleoside analogue inhibitor acts on HBV DNA polymerase |
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Definition
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Term
This adenosine monophosphate analog interferes with DNA polymerase and reverse transcriptase
It is used for HIV and lamivudine resistant HBV |
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Definition
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Term
| This cytokine is used in the treatment of HIV and has been shown to increase CD4 counts |
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Definition
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|
Term
These cytokines promote a cellular anti-viral lstate
It is used to treat hepatitis C |
|
Definition
| Interferons-alpha, beta, gamma |
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|
Term
This drug blocks DNA poymerase activity
It is frequently given to pregnant women in developing countries as a single dose at the time of delivery to prevent HIV transmission |
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Definition
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|
Term
| This was the first protease inhibitor approved for HIV |
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Definition
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|
Term
This drug prevents fusion of HIV with the target cell membrane
It is used as part of a "salvage" regimen |
|
Definition
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Term
| Name the four major classes of HIV drugs on the market |
|
Definition
1. reverse transcriptase inhibitors
a. nucleoside e.g. AZT
b. non-nucleoside e.g. Nevirapine
2. protease inhibitors (most drugs ending in avir)
3. entry inhibitors
a. coreceptor binding e.g. Maraviroc
b. fusion inhibitor e.g Enfuvirtide
4. integrase inhibitors e.g. Raltegravir
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Term
| This drug is used for the topical treatment of herpetic keratitis |
|
Definition
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|
Term
| This 21 nucleotide antisense drug is used to suppress reactivation of CMV retinitis |
|
Definition
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|
Term
This nucleoside analog is active against CMV and other herpesviruses
toxicites: nephrotoxicity, neurtropenia, metabolic acidosis |
|
Definition
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|
Term
This thymidine analog is an inhibitor of HBV DNA polymerase
it is well absorbed, has greater activity than lamivudine and resistance is less common |
|
Definition
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|
Term
| This immunomodular stimualtes TLR-7 and is used in the treatment of warts caused by papillomavirus |
|
Definition
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|
Term
| This drug is used for treatment of common warts and causes a local burning sensation in 50% of patients |
|
Definition
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Term
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Definition
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