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Anti-Ischemics
Hadleys Lecture
7
Medical
Graduate
01/19/2013

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Cards

Term
Beta-Blockers
Definition
1. prophylactic drug of choice stable angina
2. most useful Acute Coronary Syndrome
3.Not good for varient angina

CONTRAINDICATED WITH AV NODE BLOCK
Term
Nitroglycerine/Isosorbide dinitrate
Definition
Aldehyde dehydrogenase activates to relase cyclic GMP.

Prophylacticly need 4 hour free periods

if acute episode cant be terminated within 15 mins ==> medical emergency

can cause headaches

dont give within 24hrs

DECREASE PRELOAD
Term
Ranzolazine
Definition
Anti recurrent entry of excess Na+

used in combination with BB/dihydropyridines

NEVER USE WITH VERAPIMIL/DILTIAZEM

INCREASES DIGOXIN BY 50%
Term
Verapimil
Definition
Calcium channel blockers that not only produce vasodilation but also Decrease SA/AV and Contractility

Drug of choice for varient angina

AVOID: B-Blockers
Digoxin
Erythromycin
Term
Amlodipine
Definition
Dihydropyridine Calcium channel blockers that can cause gingival hyperplasia and diarrhea

Increase vasodilation ni arterioled and cornoary arteries

Decrease AFTERLOAD

side effects are periphral edema
Term
Diltizem
Definition
Calcium channel blockers that not only produce vasodilation but also Decrease SA/AV and Contractility

Drug of choice for varient angina

AVOID: B-Blockers
Digoxin
Erythromycin
Term
Nifedipine
Definition
Dihydropyridine Calcium channel blockers that can cause gingival hyperplasia and diarrhea

Increase vasodilation ni arterioled and cornoary arteries

Decrease AFTERLOAD

side effects are periphral edema
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